Patents by Inventor Kenneth C. Cundy

Kenneth C. Cundy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Surface modified NSAID nanoparticles
    Patent number: 5552160
    Abstract: Dispersible particles consisting essentially of a crystalline NSAID having a surface modifier adsorbed on the surface thereof in an amount sufficient to maintain an effective average particle size of less than about 400 nm. Pharmaceutical compositions containing the particles exhibit reduced gastric irritation following oral administration and/or hastened onset of action.
    Type: Grant
    Filed: March 13, 1995
    Date of Patent: September 3, 1996
    Assignee: NanoSystems L.L.C.
    Inventors: Gary G. Liversidge, Philip Conzentino, Jr., Kenneth C. Cundy, Pramod P. Sarpotdar
  • Method to reduce particle size growth during lyophilization
    Patent number: 5302401
    Abstract: This invention discloses a composition comprised of nanoparticles having a surface modifier adsorbed on the surface thereof and a cryoprotectant associated therewith, which cryoprotectant is present in an amount sufficient to form a nanoparticle-cryoprotectant composition. A preferred surface modifier is polyvinylpyrrolidone, and a preferred cryoprotectant is a carbohydrate such as sucrose. This invention further discloses a method of making nanoparticles having a surface modifier adsorbed on the surface and a cryoprotectant associated therewith, comprised of contacting said nanoparticles with the cryoprotectant for a time and under conditions sufficient to form a nanoparticle-cryoprotectant composition.
    Type: Grant
    Filed: December 9, 1992
    Date of Patent: April 12, 1994
    Assignee: Sterling Winthrop Inc.
    Inventors: Gary G. Liversidge, Christopher P. Phillips, Kenneth C. Cundy
  • Surface modified drug nanoparticles
    Patent number: 5145684
    Abstract: Dispersible particles consisting essentially of a crystalline drug substance having a surface modifier adsorbed on the surface thereof in an amount sufficient to maintain an effective average particle size of less than about 400 nm, methods for the preparation of such particles and dispersions containing the particles. Pharmaceutical compositions containing the particles exhibit unexpected bioavailability and are useful in methods of treating mammals.
    Type: Grant
    Filed: January 25, 1991
    Date of Patent: September 8, 1992
    Assignee: Sterling Drug Inc.
    Inventors: Gary G. Liversidge, Kenneth C. Cundy, John F. Bishop, David A. Czekai