Abstract: A method for producing intravenously injectable IgG comprising a particulate separation step, an ion exchange separation step and an affinity separation step, and the substantially pure, intravenously injectable IgG produced by the method.

Abstract: A self supporting fibrous matrix containing immobilized therein at least about 5% by weight of micro-particulate, with an average diameter less than 1 micron, preferably fumed silica, or alumina, and flocculating amounts of a neutral organic polymeric resin having oxygen atoms along the backbone thereof, is useful for fluid treatment and filtration processes, especially delipidization and depyrogenation of fluids such as serum.

Abstract: A self supporting fibrous matrix containing immobilized therein at least about 5% by weight of micro-particulate, with an average diameter less than 1 micron, preferably fumed silica, or alumina, and flocculating amounts of a neutral organic polymeric resin having oxygen atoms along the backbone thereof, is useful for fluid treatment and filtration processes, especially delipidization and depyrogenation of fluids such as serum.

Abstract: A method for the removal of thyroid or steroid hormones from whole human serum which comprises: contacting, at a pressure higher than 1 psi and pH of either 9.0-12.0 (thyroid hormones) or 4.0-6.0 (steroid hormones) the serum with a composite sheet, the composite sheet comprising a matrix of self-bonding fibers having interdispersed therein carbon particles, such that better than 90% of the carbon particles have an average diameter less than about 50 microns; and recovering a whole human serum having substantially undetectable amounts of hormones.

Abstract: A molecular separation column for effecting the differential distribution, between two phases, of the components of a sample flowing therethrough. The column contains a substantially homogenous solid stationary phase which comprises a porous matrix of fiber having particulate immobilized therein, wherein at least one of said fiber or particulate is effective for molecular separation. The column is characterized by a reduced pressure drop, increased axial dispersion, more uniform peak shapes and better separations at high sample loading.

Abstract: A self supporting fibrous matrix containing immobilized therein at least about 5% by weight of micro-particulate, with an average diameter less than 1 micron, preferably fumed silica, or alumina, and flocculating amounts of an organic polycationic resin and an organic polyanionic resin, is useful for fluid treatment and filtration processes, especially delipidization and depyrogenation of fluids such as serum.

Abstract: A self-supporting fibrous matrix containing immobilized therein at least about 5% by weight of microparticulate, with an average diameter less than 1 micron, preferably fumed silica, or alumina, and flocculating amounts of an organic polycationic resin and an organic polyanionic resin, is useful for fluid treatment and filtration processes, especially delipidization and depyrogenation of fluids such as serum.

Abstract: A cationic charge modified microporous membrane, process for producing said membrane and use thereof are provided. The membrane comprises a hydrophilic organic polymeric microporous membrane and a charge modifying amount of a primary cationic charge modifying agent bonded to substantially all of the wetted surfaces of the membrane. The primary charge modifying agent if a water soluble organic polymer having a molecular weight greater than about 1000 wherein each monomer thereof has at least one epoxide group capable of bonding to the surface of the membrane and at least one tertiary amine or quaternary ammonium group. Preferably, a portion of the epoxy groups on the organic polymer are bonded to a secondary charge modifying agent selected from the group consisting of:(i) aliphatic amines having at least one primary amine or at least two secondary amines; and(ii) aliphatic amines having at least one secondary amine and a carboxyl or hydroxyl substituent.

Abstract: A method for the removal of hormones from whole human serum which comprises: contacting, at a pressure higher than 1 psi the serum with a composite sheet, the composite sheet comprising a matrix of self-bonding fibers having interdispersed therein carbon particles, such that better than 90% of the carbon particles have an average diameter less than about 50 microns; and recovering a whole human serum having substantially undetectable amounts of hormones. The method is particularly useful for the removal of thyroid hormones.

Abstract: A molecular separation chromotography column for effecting the differential distribution, between two phases, of the components of a sample flowing therethrough. The column contains a substantially homogeneous solid stationary phase which comprises a porous matrix of fiber having particulate immobilized therein, wherein at least one of said fiber or particulate is effective for molecular separation. The column is characterized by a reduced pressure drop, increased axial dispersion, more uniform peak shapes and better separations at high sample loading.

Abstract: A filter media sheet comprising fine particulate and a self-bonding matrix of cellulose fiber, the surfaces of at least one of which are modified with cationic colloidal silica.

Abstract: A filter media is provided which comprises an amount of particulate immobilized in a substantially inert porous matrix. A least a portion of the particulate surface has thereon a divalent metal peroxide. The metal peroxide is magnesium peroxide or calcium peroxide, preferably magnesium peroxide.The filter media is preferably used for oxidizing and removing soluble iron and manganese from an aqueous fluid. The filter may also be used for removing and inactivating microorganisms from fluids, e.g. aqueous fluids. Particulate filter aid having coated or adsorbed on the surface the aforementioned metal peroxide may be used as the particulate in the filter media, as well as the metal peroxide in particulate form.

Abstract: Filter media sheets comprising particulate retention aid consisting of cellulose pulp of +100 to -100 Canadian Standard Freeness, and method of making the same.

Abstract: A filter media sheet comprising fine particulate and a self-bonding matrix of cellulose fiber, the surfaces of at least one of which are modified with cationic colloidal silica.

Abstract: Process for production of anionically charged filter media sheet including pretreatment of filter elements with cationic charge modifier, preferably employing inorganic colloidal silica charge modifiers. The resulting filters are used for the removal of haze or haze formers from beverages.

Abstract: Porous wound cartridge filters comprising a tubular element defined by superposed windings of a continuous yarn bundle, the surfaces of which are modified with cationic colloidal silica.