Patents by Inventor Kenneth D. Karlin

Kenneth D. Karlin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Dinuclear copper-based compound and ligand for nucleic acid scission and anticancer treatment
    Patent number: 7390832
    Abstract: The present invention is related to a novel method for oxidizing or splitting nucleic acids at specific points on a complementary nucleic acid segment using a dinuclear copper-based compound of Formula I. Additionally, the present invention is related to a novel treatment of cancer, tumors, and cancer cells using a dinuclear copper-based compound of formula I or a naked ligand of Formula II.
    Type: Grant
    Filed: November 12, 2002
    Date of Patent: June 24, 2008
    Assignees: The University of Maryland, The Johns Hopkins University
    Inventors: Steven E. Rokita, Kenneth D. Karlin, Lei Li, Narasimha N. Murthy
  • Dinuclear copper-based compound and ligand for nucleic acid scission and anticancer treatment
    Patent number: 7365060
    Abstract: The present invention is related to a novel method for splitting nucleic acids at specific points on a complementary nucleic acid segment using a dinuclear copper-based compound of Formula I. Additionally, the present invention is related to a novel treatment of cancer, tumors, and cancer cells using a dinuclear copper-based compound of Formula I or a naked ligand of formula II: (Formula I and II).
    Type: Grant
    Filed: November 12, 2002
    Date of Patent: April 29, 2008
    Assignee: University of Maryland
    Inventors: Steven E. Rokita, Kenneth D. Karlin, Kristi J. Humphreys, Lei Li, Narasimha N. Murthy