Abstract: An antimicrobial accessory may include a pressure sensitive adhesive and an antimicrobial mixed in the pressure sensitive adhesive. In some examples, an antimicrobial accessory may include at least one first domain comprising a pressure sensitive adhesive and a first antimicrobial and at least one second domain including a second polymer and a second antimicrobial. The antimicrobial accessory may be configured to be attached to a housing of an implantable medical device (IMD).

Abstract: A therapeutic agent reservoir comprises a reservoir body comprising a polymer and a therapeutic agent mixed within the polymer, and an outer coating enclosing the reservoir body, wherein at least a portion of the outer coating comprises a rate-controlling membrane configured to provide a predetermined release rate of the therapeutic agent through the rate-controlling membrane.

Abstract: A therapeutic agent reservoir comprises a reservoir body comprising a polymer and a therapeutic agent mixed within the polymer, and an outer coating enclosing the reservoir body, wherein at least a portion of the outer coating comprises a rate-controlling membrane configured to provide a predetermined release rate of the therapeutic agent through the rate-controlling membrane.

Abstract: A lead may include a lead body including a proximal end and a distal end, an electrode proximate to the distal end of the lead body, and a monolithic controlled release device located proximate to the electrode. According to this aspect of the disclosure, the monolithic controlled release device includes a polymer, a steroid mixed in the polymer, and an antimicrobial mixed in the polymer.

Abstract: An antimicrobial accessory may include a pressure sensitive adhesive and an antimicrobial mixed in the pressure sensitive adhesive. In some examples, an antimicrobial accessory may include at least one first domain comprising a pressure sensitive adhesive and a first antimicrobial and at least one second domain including a second polymer and a second antimicrobial. The antimicrobial accessory may be configured to be attached to a housing of an implantable medical device (IMD).

Abstract: An antimicrobial accessory may include a membrane layer defining a major surface comprising a first lateral portion, a second lateral portion, and a third lateral portion. The membrane layer may comprise a first biodegradable polymer. The antimicrobial accessory may further include a first porous layer overlying the first lateral portion and a second porous layer overlying the second lateral portion. The first porous layer comprises a second biodegradable polymer and a first antimicrobial, while the second porous layer comprises a third biodegradable polymer and a second antimicrobial.

Abstract: An implantable component including a feedthrough assembly and a method for forming the feedthrough assembly wherein a coating forming a fluid barrier over an insulator, an insulator-to-terminal pin interface and an insulator-to-ferrule interface is incorporated.

Abstract: An implantable component including a feedthrough assembly and a method for forming the feedthrough assembly wherein a coating forming a fluid barrier over an insulator, an insulator-to-terminal pin interface and an insulator-to-ferrule interface is incorporated.

Abstract: An implantable component including a feedthrough assembly and a method for forming the feedthrough assembly wherein a coating forming a fluid barrier over an insulator, an insulator-to-terminal pin interface and an insulator-to-ferrule interface is incorporated.

Abstract: An anti-microbial component of the IMD that is exposed to body fluids in the pocket is compounded of an anti-microbial metal ion zeolite that elutes metal ions in concentrations exhibiting anti-microbial activity over a substantial period of time of implantation is disclosed. The anti-microbial component is physically attached to the IMD to be retained in close proximity and in a stable location in the subcutaneous pocket. In another embodiment, the anti-microbial component conforms to the shape of the IMD and is attachable to and detachable from the IMD. In another embodiment, the polymeric component includes a connector header of an IPG or a monitor, or a connector sleeve or the sealing rings of a proximal connector assembly of an electrical medical lead coupled with an IPG or monitor that are located in the subcutaneous pocket or in the backing of a subcutaneously implanted cardioversion/defibrillation (C/D) electrode.

Abstract: This invention relates to an apparatus and a method for improving slip characteristics on the surface of a polymeric material, such as an outer surface, inner surface, or both of polymeric tubing.

Abstract: Polymeric tubing having an outer surface with a reduced coefficient of friction. The outer surface is treated by an exposure to a plasma glow discharge in the presence of an inert gas, and by deposition of a monomer during exposure to the plasma glow discharge for a time sufficient to modify the slip characteristics of the surface of the tube. The tube is preferably exposed to plasma glow discharge for a time sufficient to reduce the coefficient of friction by at least 70%. The tubing may be fabricated of silicone rubber, and the monomer deposited may be N-vinyl-2-pyrrolidone.

Abstract: An implantable medical device has an electrode lead having an outer surface of a polymeric material which has been treated in an inert gas atmosphere by a glow discharge to deposit a monomer substance thereon to produce an outer surface lower in resistance to movement within the body tissue of a patient than untreated material.

Abstract: A biomedical lead conductor body formed of a coiled wire conductor that is sheathed loosely within a coiled insulative sheath of biocompatible and biostable material allowing a gap or space to be present between the exterior surface of the coiled wire conductor and the adjacent interior surface of the insulative sheath. The coiled insulative sheath is loosely fitted around the coiled wire conductor in order to compensate for defects in the coiled insulative sheath by spreading any corrosion of the wire that may take place because of the defect away from the site of a defect and along the surface of the coiled wire conductor. The lead body is incorporated into unipolar, bipolar or multi-polar biomedical leads having single filar coil windings, or multi-filar coil windings that may be redundantly electrically connected. The coiled wire conductors and coiled insulative sheaths may be parallel-wound and/or coaxially wound within the outer lead body insulative sheath.

Abstract: The present invention provides resistance to degradation from environmental stress cracking (ESC) and metal ion induced oxidation (MIO) for implantable, flexible pacing lead insulators having a body of polyether polyurethane elastomer material. A thin layer of a second polyurethane elastomer is applied as an overcoat to the lead insulator body. The second polyurethane is more resistant to ESC and MIO than the elastomer comprising the body of the insulator. Because ESC and MIO are surface phenomina, only a thin layer of the second material is required and the mechanical properties of the base material will determine the overall mechanical properties of the lead insulator.

Abstract: The present invention provides resistance to degradation from environmental stress cracking (ESC) and metal ion induced oxidation (MIO) for implantable, flexible pacing lead insulators having a body of polyether polyurethane elastomer material. A thin layer of a second polyurethane elastomer is applied as an overcoat to the lead insulator body. The second polyurethane is more resistant to ESC and MIO than the elastomer comprising the body of the insulator. Because ESC and MIO are surface phenomina, only a thin layer of the second material is required and the mechanical properties of the base material will determine the overall mechanical properties of the lead insulator.

Abstract: An implantable lead including one or more sigmoidal or serpentine shaped conductors which are placed in one or more lumens formed in and extending along the length of the lead body. The conductor is shaped with its undulating curve lying generally in one plane. The lumen in cross section is greater in width than in height. The sigmoidal conductor extends along the length of the lead body and across the width of the lumen.

Abstract: An implantable multi-lumen, multi-conductor lead for use with an implantable medical device. The completed lead is an assembly of a polymeric lead body with several coiled conductors inserted into the lead body. The lead body includes several lumens having a generally rounded-corner triangular or "pie-shaped" cross-section. The conductors do not fill the lumens, and only contact the inner walls of the lumens at discrete points, rather than for extended sections of or all of the circumference of the conductors. Preferably the coils are sized so that they fit loosely within the lumens.

Abstract: A cardiac pacing lead has a plurality of individually insulated conductors arranged as a multifilar coil. The lead includes a connector assembly and a ring electrode assembly, each of which are optimized for use in conjunction with conductors arranged in the form of a multifilar coil. The connector assembly takes the form of an in-line connector having a plurality of linearly arranged connecting surfaces, each coupled to one of the conductors in the multifilar coil. The ring electrode assembly is constructed such that it displays the same outer diameter as the pacing lead. In both assemblies, conductors are coupled by means of welds, rather than by crimping or swaging.