Patents by Inventor Kenneth Eckels

Kenneth Eckels has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MULTIVALENT DENGUE VIRUS VACCINE
    Publication number: 20070087015
    Abstract: The present invention provides vaccine compositions of attenuated dengue virus. More specifically, the attenuated virus is produced by serial passage in PDK cells. The invention also provides methods for stimulating the immune system of an individual to induce protection against all four dengue virus serotypes by administration of attenuated dengue-1, dengue-2, dengue-3, and dengue-4 virus.
    Type: Application
    Filed: July 24, 2003
    Publication date: April 19, 2007
    Inventors: Kenneth Eckels, Joseph Putnak, Doria Dubois, Bruce Innis, Charles Hoke, Wellington Sun, Niranjan Kanesa-Thasan
  • Inactivated dengue virus vaccine
    Patent number: 6254873
    Abstract: An inactivated dengue virus vaccine to immunize and protect humans against dengue fever is described. The vaccine is based on dengue viruses which have been propagated to high titers in suitable cells, purified and inactivated under conditions which destroy infectivity but preserve immunogenicity, a high level of which is demonstrated in animal models.
    Type: Grant
    Filed: April 17, 1995
    Date of Patent: July 3, 2001
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventors: J. Robert Putnak, Kenneth Eckels, Doris R. Dubois
  • Method and kit for detection of dengue virus
    Patent number: 6190859
    Abstract: An inactivated dengue virus vaccine to immunize and protect humans against dengue fever is described. The vaccine is based on dengue viruses which have been propagated to high titers in suitable cells, purified and inactivated under conditions which destroy infectivity but preserve immunogenicity, a high level of which is demonstrated in animal models. Uses of the inactivated dengue virus for detecting antibodies to dengue and kits therefor are also described.
    Type: Grant
    Filed: April 17, 1995
    Date of Patent: February 20, 2001
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventors: J. Robert Putnak, Kenneth Eckels, Doria R. Dubois, Kevin Cassidy