Patents by Inventor Kenneth Edmund Keller

Kenneth Edmund Keller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polymeric contrast agents for medical imaging
    Patent number: 5801228
    Abstract: The invention provides polymeric polychelants containing polymer repeat units of formula ?L--Ch--L--B! (where Ch is a polydentate chelant moiety; L is an amide or ester linkage; B is a hydrophobic group providing a carbon chain of at least 4 carbon atoms between the L linkages it interconnects) or a salt or chelate thereof, with the proviso that where Ch is 2,5-biscarboxymethyl-2,5-diazahex-1,6-diyl, the polychelant is metallated with lanthanide or manganese ions or B provides a carbon chain of at least 10 carbon atoms between the L linkages it interconnects and their salts and chelates. The paramagnetic polychelates of the polychelants of the invention have remarkably high R.sub.1 relaxivities.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: September 1, 1998
    Assignee: Nycomed Imaging AS
    Inventors: Kenneth Robert Hollister, Kenneth Edmund Keller, Dong Wei, Xin Peng, David Lee Ladd, Paul Mark Henrichs, Robert Allen Snow