Patents by Inventor Kenneth F. Manly

Kenneth F. Manly has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for detecting LDH.sub.k isozyme activity in human serum for use as a diagnostic aid and for monitoring response to cancer therapy
    Patent number: 4654301
    Abstract: An improved assay procedure for quantitatively detecting LDH.sub.k isozyme in human serum is provided which utilizes previously known electrophoretic gel separation procedures combined with an improved staining method wherein the staining solution has a constant temperature of about 37.degree. C. and a pH of about 8.0, and is contacted with the gel matrix for at least 3 hours in the absence of oxygen and light. This improved assay procedure may be used as an adjunct to other procedures for diagnosing the presence of primary cancer, as a post-operative indicator of metastatic cancer and in monitoring the success of cancer therapy.
    Type: Grant
    Filed: September 9, 1985
    Date of Patent: March 31, 1987
    Assignee: Health Research, Inc. (Roswell Park Division)
    Inventors: Garth R. Anderson, Kenneth F. Manly, Arnold Mittelman
  • Process for detecting LDH.sub.k isozyme activity in human serum for use as a diagnostic aid and for monitoring response to cancer therapy
    Patent number: 4558007
    Abstract: An improved assay procedure for quantitatively detecting LDH.sub.k isozyme in human serum is provided which utilizes previously known electrophoretic gel separation procedures combined with an improved staining method wherein the staining solution has a constant temperature of about 37.degree. C. and a pH of about 8.0, and is contacted with the gel matrix for at least 3 hours in the absence of oxygen and light. This improved assay procedure may be used as an adjunct to other procedures for diagnosing the presence of primary cancer, as a post-operative indicator of metastatic cancer and in monitoring the success of cancer therapy.
    Type: Grant
    Filed: June 17, 1983
    Date of Patent: December 10, 1985
    Assignee: Health Research, Inc. (Roswell Park Divison)
    Inventors: Garth R. Anderson, Kenneth F. Manly, Arnold Mittelman