Patents by Inventor Kenneth F. Reardon

Kenneth F. Reardon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11827917
    Abstract: Methods and systems for the enhancement of bioproduct process yields. The present invention provides systems and methods for improvement of the carbon conversion efficiency by yeast of an organic substrate such as a fermentable sugar to a fermentation product such as ethanol. Exemplary yield-increasing/growth-inhibitory compounds include tyrosol (TyrOH), 2-phenylethanol (PheOH), and tryptophol (TrpOH). Immobilization of the yeast, such as in a porous bead or pellet, can further increase yield. Exemplary immobilization included immobilization in calcium alginate beads. The system and methods taught herein demonstrate that product yield such as ethanol yield can be improved by adding yeast yield-increasing/growth-inhibitory molecules to reduce cell growth of yeast species, such as S. cerevisiae, suggesting a strategy to improve the yield of ethanol and other yeast fermentation products by manipulating native biological control systems.
    Type: Grant
    Filed: April 26, 2021
    Date of Patent: November 28, 2023
    Assignee: Colorado State University Research Foundation
    Inventors: Kenneth F. Reardon, Xingfeng Huang
  • Patent number: 10024797
    Abstract: Herein disclosed are biosensing systems that measure lactose concentration in a solution.
    Type: Grant
    Filed: November 22, 2011
    Date of Patent: July 17, 2018
    Assignee: Colorado State University Research Foundation
    Inventors: Kenneth F. Reardon, David S. Dandy, Ryan E. Holcomb
  • Patent number: 9896712
    Abstract: The present disclosure relates to biosensing systems and biosensing elements having increased storage capability and increased functional lifetimes through using compositions and methods for recycling cofactors.
    Type: Grant
    Filed: October 6, 2015
    Date of Patent: February 20, 2018
    Assignee: Colorado State University Research Foundation
    Inventor: Kenneth F. Reardon
  • Patent number: 9796998
    Abstract: A biosensing system that measures the concentration of halogenated alkenes is disclosed.
    Type: Grant
    Filed: October 1, 2012
    Date of Patent: October 24, 2017
    Assignee: COLORADO STATE UNIVERSITY RESEARCH FOUNDATION
    Inventors: Kenneth F. Reardon, Brian C. Heinze
  • Publication number: 20170269001
    Abstract: A biosensing system that measures the concentration of halogenated alkenes is disclosed.
    Type: Application
    Filed: October 1, 2012
    Publication date: September 21, 2017
    Applicant: Colorado State University Research Foundation
    Inventors: Kenneth F. Reardon, Brian C. Heinze
  • Publication number: 20170009270
    Abstract: Enzymatic biosensors and methods of producing distal tips for biosensor transducers for use in detecting one or more analytes selected from organic compounds susceptible to dehalogenation, organic compounds susceptible to oxygenation and organophosphate compounds susceptible to hydrolysis are disclosed herein, as well as biosensor arrays, methods of detecting and quantifying analytes within a mixture, and devices and methods for delivering reagents to enzymes disposed within the distal tip of a biosensor.
    Type: Application
    Filed: September 26, 2016
    Publication date: January 12, 2017
    Inventors: Kenneth F. REARDON, David S. DANDY, Thomas K. WOOD, Michael FRITZSCHE
  • Patent number: 9499853
    Abstract: The present disclosure relates to biosensing systems and biosensing elements having increased storage capability and increased functional lifetimes through using compositions and methods for recycling cofactors.
    Type: Grant
    Filed: August 2, 2012
    Date of Patent: November 22, 2016
    Assignee: COLORADO STATE UNIVERSITY RESEARCH FOUNDATION
    Inventor: Kenneth F. Reardon
  • Patent number: 9493805
    Abstract: Enzymatic biosensors and methods of producing distal tips for biosensor transducers for use in detecting one or more analytes selected from organic compounds susceptible to dehalogenation, organic compounds susceptible to oxygenation and organophosphate compounds susceptible to hydrolysis are disclosed herein, as well as biosensor arrays, methods of detecting and quantifying analytes within a mixture, and devices and methods for delivering reagents to enzymes disposed within the distal tip of a biosensor.
    Type: Grant
    Filed: April 9, 2008
    Date of Patent: November 15, 2016
    Assignee: COLORADO STATE UNIVERSITY RESEARCH FOUNDATION
    Inventors: Kenneth F. Reardon, David S. Dandy, Michael Fritzsche, Thomas K. Wood
  • Patent number: 9493806
    Abstract: Biosensors and methods of producing biosensors for use in detecting one or more analytes in a solution are disclosed herein.
    Type: Grant
    Filed: July 31, 2012
    Date of Patent: November 15, 2016
    Assignee: COLORADO STATE UNIVERSITY RESEARCH FOUNDATION
    Inventor: Kenneth F. Reardon
  • Publication number: 20160024552
    Abstract: The present disclosure relates to biosensing systems and biosensing elements having increased storage capability and increased functional lifetimes through using compositions and methods for recycling cofactors.
    Type: Application
    Filed: October 6, 2015
    Publication date: January 28, 2016
    Inventor: Kenneth F. Reardon
  • Publication number: 20150232913
    Abstract: The present disclosure relates generally to the materials and methods involving biosensing systems. More specifically, the present disclosure relates to biosensors for making real-time, continuous, and quantitative assessments of analyte concentrations in aqueous environments using oxidases. The present disclosure addresses the need for improved methods and systems for making quantitative assessments of various analytes in a continuous and real-time manner, without the need for expensive and time-consuming laboratory processing.
    Type: Application
    Filed: April 30, 2015
    Publication date: August 20, 2015
    Applicant: OptiEnz Sensors, LLC
    Inventors: Kenneth F. Reardon, Brian Heinze, Jonathan Vickers, Kyle Smith, Xingfeng Huang, Lauren Magliozzi, Zachary Menard, Devon Osbourne
  • Publication number: 20140234882
    Abstract: A biosensing system that measures the concentration of halogenated alkenes is disclosed.
    Type: Application
    Filed: October 1, 2012
    Publication date: August 21, 2014
    Applicant: Colorado State University Research Foundation
    Inventors: Kenneth F. Reardon, Brian C. Heinze
  • Publication number: 20140235501
    Abstract: Biosensors and methods of producing biosensors for use in detecting one or more analytes in a solution are disclosed herein.
    Type: Application
    Filed: July 31, 2012
    Publication date: August 21, 2014
    Inventor: Kenneth F. Reardon
  • Publication number: 20140154724
    Abstract: The present disclosure relates to biosensing systems and biosensing elements having increased storage capability and increased functional lifetimes through using compositions and methods for recycling cofactors.
    Type: Application
    Filed: August 2, 2012
    Publication date: June 5, 2014
    Applicant: COLORADO STATE UNIVERSITY RESEARCH FOUNDATION
    Inventor: Kenneth F. Reardon
  • Publication number: 20130244266
    Abstract: Herein disclosed are biosensing systems that measure lactose concentration in a solution.
    Type: Application
    Filed: November 22, 2011
    Publication date: September 19, 2013
    Inventors: Kenneth F. Reardon, David S. Dandy, Ryan E. Holcomb
  • Patent number: 8323956
    Abstract: Enzymatic biosensors and methods of producing distal tips for biosensor transducers for use in detecting one or more analytes selected from organic compounds susceptible to dehalogenation, organic compounds susceptible to oxygenation, organic compounds susceptible to deamination, organosulfate compounds susceptible to hydrolysis, and organophosphate compounds susceptible to hydrolysis are disclosed herein, as well as biosensor arrays, methods of detecting and quantifying analytes within a mixture, and devices and methods for delivering reagents to enzymes disposed within the distal tip of a biosensor.
    Type: Grant
    Filed: January 22, 2009
    Date of Patent: December 4, 2012
    Assignee: Colorado State University Research Foundation
    Inventors: Kenneth F. Reardon, Lawrence Philip Wackett
  • Publication number: 20090221014
    Abstract: Enzymatic biosensors and methods of producing distal tips for biosensor transducers for use in detecting one or more analytes selected from organic compounds susceptible to dehalogenation, organic compounds susceptible to oxygenation, organic compounds susceptible to deamination, organosulfate compounds susceptible to hydrolysis, and organophosphate compounds susceptible to hydrolysis are disclosed herein, as well as biosensor arrays, methods of detecting and quantifying analytes within a mixture, and devices and methods for delivering reagents to enzymes disposed within the distal tip of a biosensor.
    Type: Application
    Filed: January 22, 2009
    Publication date: September 3, 2009
    Inventors: Kenneth F. REARDON, Lawrence Philip Wackett
  • Publication number: 20090026092
    Abstract: Enzymatic biosensors and methods of producing distal tips for biosensor transducers for use in detecting one or more analytes selected from organic compounds susceptible to dehalogenation, organic compounds susceptible to oxygenation and organophosphate compounds susceptible to hydrolysis are disclosed herein, as well as biosensor arrays, methods of detecting and quantifying analytes within a mixture, and devices and methods for delivering reagents to enzymes disposed within the distal tip of a biosensor.
    Type: Application
    Filed: April 9, 2008
    Publication date: January 29, 2009
    Inventors: Kenneth F. REARDON, David S. DANDY, Michael FRITZSCHE, Thomas K. WOOD
  • Patent number: 7381538
    Abstract: A distal tip, and associated method of producing, of a biosensor ion sensing transducer for use in detecting an analyte comprising an halogenated organic compound in an environment such as soil or an aqueous environment. Features include: a biocomponent comprising at least one enzyme for carrying out a dehalogenation of the compound; the biocomponent is immobilized to a surface of the tip; a treatment of the biocomponent for maintaining a period of enzymatic efficacy; and the biocomponent stabilized by means preferably selected from the group consisting of crosslinking a surface of the immobilized biocomponent, crosslinking a polymer layer to the biocomponent, adding a gel-hardening agent to the biocomponent, adding a stabilizing agent to the biocomponent, and modifying a component of the immobilizing means. Immobilization can be carried out by: (a) entrapment within a hydrogel; (b) entrapment within a polymeric network; (c) (micro)encapsulation; (d) covalent-bonding; and (e) adsorption.
    Type: Grant
    Filed: June 1, 2002
    Date of Patent: June 3, 2008
    Assignee: Colorado State University Research Foundation (CSURF)
    Inventors: Kenneth F. Reardon, Neema Das
  • Publication number: 20040265811
    Abstract: A distal tip, and associated method of producing, of a biosensor ion sensing transducer for use in detecting an analyte comprising an halogenated organic compound in an environment such as soil or an aqueous environment. Features include: a biocomponent comprising at least one enzyme for carrying out a dehalogenation of the compound; the biocomponent is immobilized to a surface of the tip; a treatment of the biocomponent for maintaining a period of enzymatic efficacy; and the biocomponent stabilized by means preferably selected from the group consisting of crosslinking a surface of the immobilized biocomponent, crosslinking a polymer layer to the biocomponent, adding a gel-hardening agent to the biocomponent, adding a stabilizing agent to the biocomponent, and modifying a component of the immobilizing means. Immobilization can be carried out by: (a) entrapment within a hydrogel; (b) entrapment within a polymeric network; (c) (micro)encapsulation; (d) covalent-bonding; and (e) adsorption.
    Type: Application
    Filed: August 9, 2004
    Publication date: December 30, 2004
    Inventors: Kenneth F Reardon, Neema Das