Abstract: A method determining a degree of similarity between a first sample and a second sample, comprising using a processor to compare a first thermogram and a second thermogram, each obtained by performing scanning calorimetry on a first and second sample respectively, by: determining a smoothed first thermogram and a smoothed second thermogram by respectively performing a smoothing operation on the first thermogram and the second thermogram; determining a processed first thermogram and a processed second thermogram by respectively finding a derivative of the smoothed first thermogram and the smoothed second thermogram; determining the degree of similarity from a correlation operation comparing the processed first thermogram with the processed second thermogram.

Abstract: A method determining a degree of similarity between a first sample and a second sample, comprising using a processor to compare a first thermogram and a second thermogram, each obtained by performing scanning calorimetry on a first and second sample respectively, by: determining a smoothed first thermogram and a smoothed second thermogram by respectively performing a smoothing operation on the first thermogram and the second thermogram; determining a processed first thermogram and a processed second thermogram by respectively finding a derivative of the smoothed first thermogram and the smoothed second thermogram; determining the degree of similarity from a correlation operation comparing the processed first thermogram with the processed second thermogram.

Abstract: Viscometers and viscometry methods are disclosed. In one general aspect, a fluid is driven through capillary tubes with different inside volumes, and successive images of the fluid are acquired as it advances through the inside volume of the capillary tubes. A range of different viscosity values of the fluid are derived from the successive acquired images, and results of this step are reported in a manner that provides insight into non-Newtonian effects in the fluid. In another general aspect, a viscosity value is selected based on detected pressure levels.

Abstract: The invention relates to methods and apparatus for detecting properties of heterogeneous samples, including detecting properties of particles or fluid droplets in industrial processes. Embodiments disclosed include a particle characterization method, comprising: providing a fluid containing suspended particles; causing at least a first subset of the suspended particles to flow past a first two-dimensional array detector (24); illuminating the first subset of suspended particles as they flow past the first two-dimensional array detector (24) in the fluid; acquiring a plurality of images of the first subset of particles as they flow past the first two-dimensional array detector (24) in the fluid; and automatically counting the particles in the images.

Abstract: The invention relates to methods and apparatus for detecting properties of heterogeneous samples, including detecting properties of particles or fluid droplets in industrial processes. Embodiments disclosed include a particle characterization method, comprising: providing a fluid containing suspended particles; causing at least a first subset of the suspended particles to flow past a first two-dimensional array detector (24); illuminating the first subset of suspended particles as they flow past the first two-dimensional array detector (24) in the fluid; acquiring a plurality of images of the first subset of particles as they flow past the first two-dimensional array detector (24) in the fluid; and automatically counting the particles in the images.

Abstract: A viscometer, comprising: a source of fluid pressure, a tube, an array of optical detectors, an acquisition driver circuit and viscosity computation logic. The tube has an inside volume that is hydraulically responsive to the source of fluid pressure. The array of optical detectors is positioned along a length of the first tube with a plurality of its detectors optically responsive to the inside volume of the first tube and including an image data output. The acquisition driver circuit is responsive to the image data output of the first array to acquire a series of successive images of the inside volume of the first tube. The viscosity computation logic is responsive to the acquisition driver circuit and operative to compute the viscosity of a fluid flowing along the first tube from the series of images of the inside volume of the first tube.

Abstract: In one general aspect, a capillary viscometer is disclosed that includes a source of fluid pressure, a pressure transducer responsive to the source of fluid pressure, and a first capillary tube having an inside volume that is hydraulically responsive to the source of fluid pressure. A two-dimensional array of optical detectors is positioned proximate the first capillary tube with a first plurality of its detectors optically responsive to the inside volume of the first capillary tube and including an image data output. An acquisition driver circuit is responsive to the image data output of the two-dimensional array to acquire a series of successive images of the inside volume of the first capillary tube. Viscosity computation logic is responsive to the acquisition driver circuit and the pressure transducer, and operative to compute the viscosity of the fluid from pressure values received from the pressure transducer and the succession of images of the inside volume of the first capillary tube.

Abstract: A method of obtaining information about a heterogeneous pharmaceutical mixture is disclosed. This method involves applying an image enhancement agent, such as a stain, to the mixture. An image of the mixture can then be obtained, and information about a distribution of components of the mixture in the image can also be obtained based on spatial information derived from the application of the image enhancement agent.