Patents by Inventor Kenneth Hinds
Kenneth Hinds has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20230066143Abstract: A document may be received as part of a request to identify similar documents in a collection of documents. However, the received document and the documents in the collection may have different schemas or formats. To provide semantic context to the search and allow similarity scores to be generated between different document types, a configuration may be accessed that defines how to generate queries from one schema into another schema. The configuration may map queries between different fields in both schemas. Results of the multiple queries can be combined to generate a weighted combination for each document that can be used as a similarity score between different document types.Type: ApplicationFiled: September 1, 2021Publication date: March 2, 2023Applicant: Oracle International CorporationInventors: Liviu Sebastian Matei, Filip Trojan, Marc Michiel Bron, Andrew Kenneth Hind, Yingzhao Zhou, Maria-Monica Petrica, Rajesh Ashwinbhai Shah
-
Patent number: 9789196Abstract: The invention is directed to a single-step method for rapidly and efficiently preparing protein-polymer conjugates, including an insulin-polymer conjugate. According to the method of the present invention, a protein and hydrophilic polymer are contacted in the presence of at least one organic solvent and at least one metal chelator, under conditions that promote the formation of a conjugate of the protein and polymer. Thus, the invention is directed to the site-specific modification of selected proteins, such as insulin, with poly(ethylene glycol) at residue PheB1. The invention also provides a pharmaceutical formulation for encapsulating the conjugate in a biodegradable polymer.Type: GrantFiled: April 21, 2015Date of Patent: October 17, 2017Assignee: ANTRIABIO, INC.Inventors: Kenneth Hinds, Danny Lewis, Paul Schmidt, Kathleen M. Campbell
-
Publication number: 20150216995Abstract: The invention is directed to a single-step method for rapidly and efficiently preparing protein-polymer conjugates, including an insulin-polymer conjugate. According to the method of the present invention, a protein and hydrophilic polymer are contacted in the presence of at least one organic solvent and at least one metal chelator, under conditions that promote the formation of a conjugate of the protein and polymer. Thus, the invention is directed to the site-specific modification of selected proteins, such as insulin, with poly(ethylene glycol) at residue PheB1. The invention also provides a pharmaceutical formulation for encapsulating the conjugate in a biodegradable polymer.Type: ApplicationFiled: April 21, 2015Publication date: August 6, 2015Inventors: Kenneth Hinds, Danny Lewis, Paul Schmidt, Kathleen M. Campbell
-
Patent number: 9040664Abstract: The invention is directed to a single-step method for rapidly and efficiently preparing protein-polymer conjugates, including an insulin-polymer conjugate. According to the method of the present invention, a protein and hydrophilic polymer are contacted in the presence of at least one organic solvent and at least one metal chelator, under conditions that promote the formation of a conjugate of the protein and polymer. Thus, the invention is directed to the site-specific modification of selected proteins, such as insulin, with poly(ethylene glycol) at residue PheB1. The invention also provides a pharmaceutical formulation for encapsulating the conjugate in a biodegradable polymer.Type: GrantFiled: April 8, 2004Date of Patent: May 26, 2015Assignee: AntriaBio, Inc.Inventors: Kenneth Hinds, Danny Lewis, Paul Schmidt, Kathleen M. Campbell
-
Patent number: 7476006Abstract: A lighting system includes multiple extendable and retractable light units. Each light unit includes a housing with inner and outer sleeves, which are telescopically interconnected. A drive assembly is located in each housing for extending and retracting the inner sleeve whereby a luminaire mounted in the inner sleeve can be selectively elevated. The housings are adapted for flush-mounting in the ground with their inner sleeves retracted. The lighting system can include a centralized control subsystem for collectively and individually operating the individual light units.Type: GrantFiled: July 12, 2006Date of Patent: January 13, 2009Inventor: Kenneth A. Hinds
-
Publication number: 20080292712Abstract: Formulations for controlled, prolonged release of bioactive molecules such as therapeutic proteins, peptides and oligonucleotides have been developed. These formulations are based on solid microparticles or nanoparticles formed of the combination of biodegradable, synthetic polymers such as poly (lactic acid) (PLA), poly (glycolic acid) (PGA), and copolymers thereof. Bioactive molecules are coupled to hydrophilic polymers such as polyethylene glycol or polypropylene glycol and formulated to provide controlled release. The bioactive molecules are more stable, less immunogenic and have improved release rate profiles with lower burst levels and increased drug loading relative to the same bioactive molecules lacking coupled hydrophilic polymers. The controlled release formulations can be administered by injection, by inhalation, nasally, or orally.Type: ApplicationFiled: August 5, 2008Publication date: November 27, 2008Applicant: PR PHARMACEUTICALS, INC.Inventors: Danny Lewis, Paul Schmidt, Kenneth Hinds
-
Publication number: 20080013317Abstract: A lighting system includes multiple extendable and retractable light units. Each light unit includes a housing with inner and outer sleeves, which are telescopically interconnected. A drive assembly is located in each housing for extending and retracting the inner sleeve whereby a luminaire mounted in the inner sleeve can be selectively elevated. The housings are adapted for flush-mounting in the ground with their inner sleeves retracted. The lighting system can include a centralized control subsystem for collectively and individually operating the individual light units.Type: ApplicationFiled: July 12, 2006Publication date: January 17, 2008Inventor: Kenneth A. Hinds
-
Publication number: 20070083006Abstract: The invention is directed to a single-step method for rapidly and efficiently preparing protein-polymer conjugates, including an insulin-polymer conjugate. According to the method of the present invention, a protein and hydrophilic polymer are contacted in the presence of at least one organic solvent and at least one metal chelator, under conditions that promote the formation of a conjugate of the protein and polymer. Thus, the invention is directed to the site-specific modification of selected proteins, such as insulin, with poly(ethylene glycol) at residue PheB 1. The invention also provides a pharmaceutical formulation for encapsulating the conjugate in a biodegradable polymer.Type: ApplicationFiled: April 8, 2004Publication date: April 12, 2007Applicant: PR Pharmaceuticals, Inc.Inventors: Kenneth Hinds, Danny Lewis, Paul Schmidt, Kathleen Campell
-
Publication number: 20040185103Abstract: Formulations for controlled, prolonged release of bioactive molecules such as therapeutic proteins, peptides and oligonucleotides have been developed. These formulations are based on solid microparticles or nanoparticles formed of the combination of biodegradable, synthetic polymers such as poly (lactic acid) (PLA), poly (glycolic acid) (PGA), and copolymers thereof. Bioactive molecules are coupled to hydrophilic polymers such as polyethylene glycol or polypropylene glycol and formulated to provide controlled release. The bioactive molecules are more stable, less immunogenic and have improved release rate profiles with lower burst levels and increased drug loading relative to the same bioactive molecules lacking coupled hydrophilic polymers. The controlled release formulations can be administered by injection, by inhalation, nasally, or orally.Type: ApplicationFiled: January 27, 2004Publication date: September 23, 2004Inventors: Danny Lewis, Paul Schmidt, Kenneth Hinds
-
Patent number: 6706289Abstract: Formulations for controlled, prolonged release of bioactive molecules such as therapeutic proteins, peptides and oligonucleotides have been developed. These formulations are based on solid microparticles or nanoparticles formed of the combination of biodegradable, synthetic polymers such as poly(lactic acid) (PLA), poly(glycolic acid) (PGA), and copolymers thereof. Bioactive molecules are coupled to hydrophilic polymers such as polyethylene glycol or polypropylene glycol and formulated to provide controlled release. The bioactive molecules are more stable, less immunogenic and have improved release rate profiles with lower burst levels and increased drug loading relative to the same bioactive molecules lacking coupled hydrophilic polymers. The controlled release formulations can be administered by injection, by inhalation, nasally, or orally.Type: GrantFiled: October 31, 2001Date of Patent: March 16, 2004Assignee: PR Pharmaceuticals, Inc.Inventors: Danny Lewis, Paul Schmidt, Kenneth Hinds
-
Publication number: 20020155158Abstract: Formulations for controlled, prolonged release of bioactive molecules such as therapeutic proteins, peptides and oligonucleotides have been developed. These formulations are based on solid microparticles or nanoparticles formed of the combination of biodegradable, synthetic polymers such as poly(lactic acid) (PLA), poly(glycolic acid) (PGA), and copolymers thereof. Bioactive molecules are coupled to hydrophilic polymers such as polyethylene glycol or polypropylene glycol and formulated to provide controlled release. The bioactive molecules are more stable, less immunogenic and have improved release rate profiles with lower burst levels and increased drug loading relative to the same bioactive molecules lacking coupled hydrophilic polymers. The controlled release formulations can be administered by injection, by inhalation, nasally, or orally.Type: ApplicationFiled: October 31, 2001Publication date: October 24, 2002Inventors: Danny Lewis, Paul Schmidt, Kenneth Hinds