Abstract: The invention relates to barcoded nucleic acid nanostructure delivery compositions for in vivo screening for subsequent use in vivo therapeutic delivery, and methods therefor. More particularly, the invention relates to nucleic acid nanostructure delivery compositions, such as DNA origami structures, associated with barcodes for high throughput in vivo screening of the nucleic acid nanostructure delivery compositions for subsequent use in drug delivery, and methods therefor.

Abstract: A powered air purifying respirator and method of operating the same. The powered air purifying respirator comprises a fluid moving device. The fluid moving device comprises an outlet, an airflow sensor retaining member located proximate to the outlet, and an airflow sensor engaged with the airflow sensor retaining member.

Abstract: An extra-oral capture hood includes a first cone that provides a first path for a vacuum product through the extra-oral capture hood. A second cone concentric with the first cone and disposed around the first cone provides a second path for the vacuum product through the extra-oral capture hood, the second path being located between the first cone and second cone. A disconnect is connected to at least one of the first cone or second cone, the disconnect being configured to connect the extra-oral capture hood to a duct, a valve or other component of a capture system.

Abstract: A fan comprising: (a) an impeller, (b) a motor connected to the impeller so that during operation the motor drives the impeller to move a fluid; (c) an instrumentation assembly that includes one or more components for controlling one or more operations of the fan; (d) an interface in communication with the instrumentation assembly; wherein the interface is configured so that one or more programs, one or more signals, or both can be input into the fan after a final assembly of the fan so that the fan can be configured to perform a desired function at the time of installation into a final product, reconfigured for a different purpose than originally programmed, or both.

Abstract: Systems and methods for implementing a biomedical innovations datametrics dashboard are presented. The dashboard can utilize data from real-world data sources to inform a simulation model which performs simulations of the biomedical innovation pipeline and related entities and processes. The dashboard can utilize the simulation model as well as feedback solicited from a user to assist in performing multi-objective optimization according to the user's preferences. The dashboard can help policy decision-makers and other stakeholders decide on a combination of policies that best incentivizes private sector biomedical innovation in order to achieve a satisfactory set of outcomes, which may include, but is not limited to, reductions in DALYs, healthcare costs, increases in industry NPV, and improved clinical trial quality.

Abstract: The present invention relates to a wearable (or fastenable, or adherable) vibration massage system directly localized, focused and engaged upon or overlying a selected target artery of a user. The vibration massage waves are advantageously derived from religious texts, whereby a user can simultaneously listen to audio of the in real time, thereby providing a synchronized, harmonized tactile and auditory experience. The provided system is essentially MUSical vibration applied upon a target ARTtery—hence is hereinafter described as the “MUSART” therapy system. Various modes of application of the tactile vibratory stimulus, as well as modes for invasive delivery of acoustic stimulation directly in contact with a target artery, are presented.

Abstract: A fan comprising: (a) an impeller, (b) a motor connected to the impeller so that during operation the motor drives the impeller to move a fluid; (c) an instrumentation assembly that includes one or more components for controlling one or more operations of the fan; (d) an interface in communication with the instrumentation assembly; wherein the interface is configured so that one or more programs, one or more signals, or both can be input into the fan after a final assembly of the fan so that the fan can be configured to perform a desired function at the time of installation into a final product, reconfigured for a different purpose than originally programmed, or both.

Abstract: A fan comprising: (a) an impeller, (b) a motor connected to the impeller so that during operation the motor drives the impeller to move a fluid; (c) an instrumentation assembly that includes one or more components for controlling one or more operations of the fan; (d) an interface in communication with the instrumentation assembly; wherein the interface is configured so that one or more programs, one or more signals, or both can be input into the fan after a final assembly of the fan so that the fan can be configured to perform a desired function at the time of installation into a final product, reconfigured for a different purpose than originally programmed, or both.

Abstract: Systems and methods for implementing a biomedical innovations datametrics dashboard are presented. The dashboard can utilize data from real-world data sources to inform a simulation model which performs simulations of the biomedical innovation pipeline and related entities and processes. The dashboard can utilize the simulation model as well as feedback solicited from a user to assist in performing multi-objective optimization according to the user's preferences. The dashboard can help policy decision-makers and other stakeholders decide on a combination of policies that best incentivizes private sector biomedical innovation in order to achieve a satisfactory set of outcomes, which may include, but is not limited to, reductions in DALYs, healthcare costs, increases in industry NPV, and improved clinical trial quality.

Abstract: A fan comprising: (a) an impeller, (b) a motor connected to the impeller so that during operation the motor drives the impeller to move a fluid; (c) an instrumentation assembly that includes one or more components for controlling one or more operations of the fan; (d) an interface in communication with the instrumentation assembly; wherein the interface is configured so that one or more programs, one or more signals, or both can be input into the fan after a final assembly of the fan so that the fan can be configured to perform a desired function at the time of installation into a final product, reconfigured for a different purpose than originally programmed, or both.

Abstract: A strip of multiple seals, each seal for sealing around overlying courses of strapping material to form a seal of the strapping material onto itself at the overlying courses includes an elongated strip of ductile metal. The strip has a longitudinal direction having edges and defining a longitudinal axis parallel to the edges, and a transverse direction normal to the longitudinal axis. Each seal defines a respective transverse axis. The strip has a plurality of substantially identical slots formed in the transverse direction to define the respective seals. The slots extend toward, but not to, the edges of the strip and define connecting portions between ends of the slot and the respective edges. The slots are equally spaced from one another in a longitudinal direction to define the respective seals.

Abstract: A strip of multiple seals, each seal for sealing around overlying courses of strapping material to form a seal of the strapping material onto itself at the overlying courses includes an elongated strip of ductile metal. The strip has a longitudinal direction having edges and defining a longitudinal axis parallel to the edges, and a transverse direction normal to the longitudinal axis. Each seal defines a respective transverse axis. The strip has a plurality of substantially identical slots formed in the transverse direction to define the respective seals. The slots extend toward, but not to, the edges of the strip and define connecting portions between ends of the slot and the respective edges. The slots are equally spaced from one another in a longitudinal direction to define the respective seals.

Abstract: A method and apparatus associated with transferring data from a remote device to a recipient device having a first memory space and a second memory space. The method includes issuing a transfer command from the remote device to request transferring a set of data to the second memory space; temporarily storing the set of data in the first memory space pending a transfer to the second memory space; and appending the set of data to other sequential data in the first memory to obtain a transfer data block of a predetermined size for transfer to the second memory space. A corresponding apparatus is provided comprising circuitry configured to buffer write commands by characterizing each write command as being either a sequential write or a random write, and responsively appending data associated with sequential write commands in order to obtain a transfer block of a predetermined size.

Abstract: A roof flashing strip is formed by extruding or injection molding a suitable material of either polymer or metallic material. The roof flashing strip is formed as an elongated member which then can be cut to any suitable length. The roof flashing strip includes a backing plate having a plurality of legs projecting laterally outwardly therefrom and normal thereto. The legs are inclined with respect to a horizontal plane and vertically axially displaced such that there is a gap therebetween, with portion of adjacent legs overlying and/or underlying one another. The gap enables the emplacement of a shingle thereinto.

Abstract: A cold rolled full hard steel strap usable in a strapping machine has a tensile strength of at least about 125.7 thousand pounds per square inch (KSI) when the strap has a width of about 0.500 inches and a thickness of 0.020 inches. The steel strap is fabricated from a coiled steel formed by hot mill rolling and reduced by cold rolling. The steel strap has a composition of approximately (in weight percent): 0.02 to 0.25 percent carbon, 0.15 to 1.50 percent manganese, 0.01 to 0.12 percent aluminum, 0.04 to 0.03 percent nitrogen, 0.04 to 0.50 percent copper, 0.03 to 0.25 percent nickel, 0.02 to 0.25 percent molybdenum, 0.03 to 0.25 percent chromium, maximum 0.05 percent phosphorous, maximum 0.05 percent sulfur, and maximum 0.25 percent silicon. A method for forming the strap also is disclosed.

Abstract: A method and apparatus associated with transferring data from a remote device to a recipient device having a first memory space and a second memory space. The method includes issuing a transfer command from the remote device to request transferring a set of data to the second memory space; temporarily storing the set of data in the first memory space pending a transfer to the second memory space; and appending the set of data to other sequential data in the first memory to obtain a transfer data block of a predetermined size for transfer to the second memory space. A corresponding apparatus is provided comprising circuitry configured to buffer write commands by characterizing each write command as being either a sequential write or a random write, and responsively appending data associated with sequential write commands in order to obtain a transfer block of a predetermined size.

Abstract: A cold rolled full hard steel strap usable in a strapping machine has a tensile strength of at least about 125.7 thousand pounds per square inch (KSI) when the strap has a width of about 0.500 inches and a thickness of 0.020 inches. The steel strap is fabricated from a coiled steel formed by hot mill rolling and reduced by cold rolling. The steel strap has a composition of approximately (in weight percent): 0.02 to 0.25 percent carbon, 0.15 to 1.50 percent manganese, 0.01 to 0.12 percent aluminum, 0.04 to 0.03 percent nitrogen, 0.04 to 0.50 percent copper, 0.03 to 0.25 percent nickel, 0.02 to 0.25 percent molybdenum, 0.03 to 0.25 percent chromium, maximum 0.05 percent phosphorous, maximum 0.05 percent sulfur, and maximum 0.25 percent silicon. A method for forming the strap also is disclosed.

Abstract: Embodiments of the present invention generally relate to apparatus and methods for protecting valuables during a storm or other natural disaster such as a hurricane or tornado by securing such valuables in a containment unit that an owner leaves behind in the wake of the oncoming storm. In one aspect of the present invention, the containment unit is designed to withstand the impact of the storm via a heavily constructed containment unit that includes multiple layers of waterproofing. In another aspect of the present invention, the containment unit is designed to be bolted deeply into the floor or foundation of a home or business for the purpose of keeping the containment unit in place during the ravages of the storm.

Abstract: A flashing strip is defined by at least a pair of interlocking flashing segments. Each of the segments has first and second intersecting legs, the first legs of each of the segments are brought into abutment and interlocked either by folding over into inter-engagement or by providing an embossment in each of the upper legs which are then, upon deforming of one of the first legs, and folding it over the upper edge of the second leg and mating the embossments together. Preferably, a gap is provided between the second legs of the first and second segments to define a gap for inserting a shingle therewithin.

Abstract: A roof flashing strip (10) is formed by extruding or injection molding a suitable material of either plastic or metal. The roof flashing strip (10) is formed as an elongated member (16) which then can be cut to any suitable length. The roof flashing strip (10) includes a backing plate (14) having a plurality of legs (18, 18?, 18?) projecting laterally outwardly therefrom and normal thereto. The legs (18) are inclined with respect to a horizontal plane (17) and vertically axially displaced such that there is a gap (24) therebetween, with portions of adjacent legs overlying and/or underlying one another. The gap enables the emplacement of a shingle (30) thereinto.