Abstract: There is described the calcium salt of 10-propyl-2,8-bis(1H-tetrazol-5-yl)-4H,6H-benzo(1,2-b;5,4-b')dipyran-4,6- dione and processes for its preparation.Also described are pharmaceutical compositions containing the calcium salt and methods of treatment involving its use.

Abstract: There are described compounds of formula I, ##STR1## in which R.sub.1 represents benzofurazanyl, pyridyl or phenyl, the pyridyl or phenyl being substituted,--COOR.sub.2 and --COOR.sub.3 are various ester groups,one of R.sub.7 and R.sub.8 represents alkyl Cl to 6 and the other represents --CONR.sub.10 R.sub.11 ; --CSNH.sub.2 ; --C(.dbd.NH)SR.sub.9 ; --S(O).sub.m R.sub.9 ; phenyl optionally substituted by one or more of alkyl Cl to 6, halogen, alkoxy Cl to 6 or nitro; alkyl Cl to 6 substituted by halogen; or furanyl;m is 0 or 1R.sub.9 is alkyl Cl to 6, andR.sub.10 and R.sub.11 each independently represent hydrogen or alkyl Cl to 6, or together with the nitrogen atom to which they are attached form a 5 or 6 membered heterocyclic ring.There are also described processes for making the compounds, and pharmaceutical, e.g. calcium antagonist, formulations containing them.

Abstract: There are provided benzopyrans of formula I ##STR1## wherein R.sub.6 and R.sub.7 together form the chain --CHOCH.dbd.(A.sub.1 E.sub.1)--O-- in which --O-- is attached to R.sub.7,R.sub.5 represents hydrogen,R.sub.8 represents propyl,A represents a single bond,A.sub.1 represents a single bond, phenylene or (CH.sub.2).sub.m,m represents an integer from 1 to 10 inclusive,E and E.sub.1, which may be the same or different, independently represent --COOH, 5H-tetrazolyl, or CONR.sub.24 R.sub.25, wherein R.sub.24 and R.sub.25, which may be the same or different, represent hydrogen or alkyl of C.sub.1 to C.sub.6 ;provided that when A.sub.1 represents a single bond, then E.sub.1 represents 5H-tetrazolyl or CONR.sub.24 R.sub.25, and their pharmaceutically acceptable salts, all of which are useful as anti-asthmatics.