Patents by Inventor Kenneth J. Miller, II
Kenneth J. Miller, II has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10272656Abstract: A method allows for rapid manufacture of relatively thick adhesive coatings using a continuous process, where a single thin coating is continuously converted into a single thicker adhesive laminate. An exemplary process includes the steps of: (1) producing a web having a first surface with an adhesive layer and a second surface with a release liner; (2) slitting the web longitudinally into a first section and a second section; (3) laminating a backing film to the adhesive layer of the first section; (4) removing the release liner of the laminate of step (3) exposing the adhesive layer of the first section; and (5) laminating the second section to the laminate of step (4), wherein the adhesive layer of the laminate of step (4) is combined with the adhesive layer of the second section.Type: GrantFiled: June 19, 2017Date of Patent: April 30, 2019Assignee: Mylan Inc.Inventor: Kenneth J. Miller, II
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Publication number: 20170282526Abstract: A method allows for rapid manufacture of relatively thick adhesive coatings using a continuous process, where a single thin coating is continuously converted into a single thicker adhesive laminate. An exemplary process includes the steps of: (1) producing a web having a first surface with an adhesive layer and a second surface with a release liner; (2) slitting the web longitudinally into a first section and a second section; (3) laminating a backing film to the adhesive layer of the first section; (4) removing the release liner of the laminate of step (3) exposing the adhesive layer of the first section; and (5) laminating the second section to the laminate of step (4), wherein the adhesive layer of the laminate of step (4) is combined with the adhesive layer of the second section.Type: ApplicationFiled: June 19, 2017Publication date: October 5, 2017Inventor: Kenneth J. Miller II, Ph.D.
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Patent number: 9358373Abstract: Devices for administration of one or more active agents to the skin or mucosa of a host are formed in the nature of a double-disk patch. One outer layer functions as the primary adhesive layer for adhering the patch to the host. The other inner layer contains at least one active agent to be administered to the host. The inner layer is bonded to the outer layer through an opening provided in an interposed active agent impermeable release layer. The release layer separates a circumferential portion of the active agent containing inner layer from the outer adhesive layer to inhibit migration of the active agent therebetween.Type: GrantFiled: May 15, 2014Date of Patent: June 7, 2016Assignee: Mylan Technologies IncInventor: Kenneth J. Miller, II
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Patent number: 9205062Abstract: A transdermal drug-containing dosage unit comprises: a backing layer substantially impervious to the drug to be delivered transdermally; a first polymeric adhesive matrix, in contact with the backing layer, having dispersed therein the drug and having a first delivery profile of the drug; a second polymeric adhesive matrix, in contact with said first polymeric adhesive matrix, having dispersed therein the drug and having a second delivery profile of the drug, wherein said second delivery profile is different from said first delivery profile; and a release liner in contact with the second polymeric adhesive matrix. The first polymeric adhesive matrix can release the drug more quickly or more slowly than the second polymeric adhesive matrix. Through the selection of the two matrices, the delivery profile of the drug through the skin can be selectively modified and controlled.Type: GrantFiled: November 17, 2008Date of Patent: December 8, 2015Assignee: Mylan Pharmaceuticals, Inc.Inventors: Kristin Jackson, Kenneth J. Miller, II
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Publication number: 20150246006Abstract: Transdermal delivery systems are disclosed including a backing layer, a polymer membrane within the backing layer, an adhesive layer for attaching the delivery system to the patient's skin or mucosa, and a releasable layer covering the adhesive layer prior to use, the polymer membrane impregnated with sufficient fluid medium to alter the rate of transmission of an active agent through the polymer membrane, with the amount of fluid medium being greater than the amount retained by the fluid membrane upon drying.Type: ApplicationFiled: April 30, 2015Publication date: September 3, 2015Applicant: Mylan Technologies, Inc.Inventors: Kristin Jackson, Kenneth J. Miller, II, Pavan Bhat
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Publication number: 20140249492Abstract: Devices for administration of one or more active agents to the skin or mucosa of a host are formed in the nature of a double-disk patch. One outer layer functions as the primary adhesive layer for adhering the patch to the host. The other inner layer contains at least one active agent to be administered to the host. The inner layer is bonded to the outer layer through an opening provided in an interposed active agent impermeable release layer. The release layer separates a circumferential portion of the active agent containing inner layer from the outer adhesive layer to inhibit migration of the active agent therebetween.Type: ApplicationFiled: May 15, 2014Publication date: September 4, 2014Applicant: MYLAN TECHNOLOGIES, INC.Inventor: Kenneth J. Miller, II
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Patent number: 8802136Abstract: Devices for administration of one or more active agents to the skin or mucosa of a host are formed in the nature of a double-disk patch. One outer layer functions as the primary adhesive layer for adhering the patch to the host. The other inner layer contains at least one active agent to be administered to the host. The inner layer is bonded to the outer layer through an opening provided in an interposed active agent impermeable release layer. The release layer separates a circumferential portion of the active agent containing inner layer from the outer adhesive layer to inhibit migration of the active agent therebetween.Type: GrantFiled: June 13, 2013Date of Patent: August 12, 2014Assignee: Mylan Technologies, Inc.Inventor: Kenneth J. Miller, II
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Publication number: 20130274694Abstract: Devices for administration of one or more active agents to the skin or mucosa of a host are formed in the nature of a double-disk patch. One outer layer functions as the primary adhesive layer for adhering the patch to the host. The other inner layer contains at least one active agent to be administered to the host. The inner layer is bonded to the outer layer through an opening provided in an interposed active agent impermeable release layer. The release layer separates a circumferential portion of the active agent containing inner layer from the outer adhesive layer to inhibit migration of the active agent therebetween.Type: ApplicationFiled: June 13, 2013Publication date: October 17, 2013Inventor: Kenneth J. Miller, II
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Patent number: 8524272Abstract: Devices for administration of one or more active agents to the skin or mucosa of a host are formed in the nature of a double-disk patch. One outer layer functions as the primary adhesive layer for adhering the patch to the host. The other inner layer contains at least one active agent to be administered to the host. The inner layer is bonded to the outer layer through an opening provided in an interposed active agent impermeable release layer. The release layer separates a circumferential portion of the active agent containing inner layer from the outer adhesive layer to inhibit migration of the active agent therebetween.Type: GrantFiled: August 15, 2003Date of Patent: September 3, 2013Assignee: Mylan Technologies, Inc.Inventor: Kenneth J. Miller, II
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Patent number: 8449907Abstract: Silicone adhesive formulations are provided, in which fentanyl particles are suspended one or more a solvated silicone adhesives. The formulations can be used for manufacturing improved, matrix-type transdermal devices for administering fentanyl.Type: GrantFiled: July 27, 2011Date of Patent: May 28, 2013Assignee: Mylan Pharmaceuticals, Inc.Inventors: Kenneth J. Miller, II, Sharad K. Govil, Kuljit Singh Bhatia
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Publication number: 20120078204Abstract: A transdermal drug-containing dosage unit comprises: a backing layer substantially impervious to the drug to be delivered transdermally; a first polymeric adhesive matrix, in contact with the backing layer, having dispersed therein the drug and having a first delivery profile of the drug; a second polymeric adhesive matrix, in contact with said first polymeric adhesive matrix, having dispersed therein the drug and having a second delivery profile of the drug, wherein said second delivery profile is different from said first delivery profile; and a release liner in contact with the second polymeric adhesive matrix. The first polymeric adhesive matrix can release the drug more quickly or more slowly than the second polymeric adhesive matrix. Through the selection of the two matrices, the delivery profile of the drug through the skin can be selectively modified and controlled.Type: ApplicationFiled: November 17, 2009Publication date: March 29, 2012Applicant: Mylan, Inc.Inventors: Kristin Jackson, Kenneth J. Miller, II
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Patent number: 8142592Abstract: A method allows for rapid manufacture of relatively thick adhesive coatings using a continuous process, where a single thin coating is continuously converted into a single thicker adhesive laminate. An exemplary process includes the steps of: (1) producing a web having a first surface with an adhesive layer and a second surface with a release liner; (2) slitting the web longitudinally into a first section and a second section, (3) laminating a backing film to the adhesive layer of the first section; (4) removing the release liner of the laminate of step (3) exposing the adhesive layer of the first section; and (5) laminating the second section to the laminate of step (4), wherein the adhesive layer of the laminate of step (4) is combined with the adhesive layer of the second section.Type: GrantFiled: October 1, 2009Date of Patent: March 27, 2012Assignee: Mylan Inc.Inventor: Kenneth J. Miller, II
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Publication number: 20120061018Abstract: A method allows for rapid manufacture of relatively thick adhesive coatings using a continuous process, where a single thin coating is continuously converted into a single thicker adhesive laminate. An exemplary process includes the steps of: (1) producing a web having a first surface with an adhesive layer and a second surface with a release liner; (2) slitting the web longitudinally into a first section and a second section; (3) laminating a backing film to the adhesive layer of the first section; (4) removing the release liner of the laminate of step (3) exposing the adhesive layer of the first section; and (5) laminating the second section to the laminate of step (4), wherein the adhesive layer of the laminate of step (4) is combined with the adhesive layer of the second section.Type: ApplicationFiled: November 18, 2011Publication date: March 15, 2012Inventor: Kenneth J. Miller, II
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Patent number: 7955677Abstract: Assemblies for the adhesive attachment to the skin or mucosa of a host are disclosed. The assembly or transdermal patch includes an outer backing layer, a first layer of adhesive on the inner surface of the outer backing layer, an inner backing layer, and an intermediate release liner between the first layer of adhesive and the inner backing layer. The intermediate release liner includes a releasable surface on both its inner and outer surfaces.Type: GrantFiled: December 7, 2005Date of Patent: June 7, 2011Assignee: Mylan Technologies, Inc.Inventors: Brad L. Barnett, Martin Fletcher, Kenneth J. Miller, II
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Publication number: 20100086582Abstract: The present invention refers to a transdermal delivery device comprising a backing layer, an adhesive matrix layer comprising a supersaturated concentration of rotigotine substantially in amorphous form within the adhesive matrix, and a release liner. The present invention also refers to a method of preparing an adhesive matrix containing a supersaturated amount of rotigotine substantially in amorphous form. Further, the present invention refers to a method of stabilizing and a method of reestablishing the meta-stable amorphous-drug transdermal system during its manufacturing, storing, shipping and handling process.Type: ApplicationFiled: October 1, 2009Publication date: April 8, 2010Applicant: MYLAN TECHNOLOGIES, INC.Inventors: Jiansheng Tang, Joseph M. Deverich, Kenneth J. Miller, II, Russell D. Beste
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Publication number: 20100084084Abstract: A method allows for rapid manufacture of relatively thick adhesive coatings using a continuous process, where a single thin coating is continuously converted into a single thicker adhesive laminate.Type: ApplicationFiled: October 1, 2009Publication date: April 8, 2010Inventor: Kenneth J. Miller, II
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Publication number: 20090238861Abstract: Silicone adhesive formulations are provided, in which fentanyl particles are suspended one or more a solvated silicone adhesives. The formulations can be used for manufacturing improved, matrix-type transdermal devices for administering fentanyl.Type: ApplicationFiled: June 2, 2009Publication date: September 24, 2009Applicant: Mylan Pharmaceuticals, Inc.Inventors: Kenneth J. Miller, II, Sharad K. Govil, Kuljit Singh Bhatia
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Publication number: 20090234308Abstract: Transdermal delivery systems are disclosed including a backing layer, a polymer membrane within the backing layer, an adhesive layer for attaching the delivery system to the patient's skin or mucosa, and a releasable layer covering the adhesive layer prior to use, the polymer membrane impregnated with sufficient fluid medium to alter the rate of transmission of an active agent through the polymer membrane, with the amount of fluid medium being greater than the amount retained by the fluid membrane upon drying.Type: ApplicationFiled: May 22, 2009Publication date: September 17, 2009Applicant: Mylan Technologies, Inc.Inventors: Kristin Jackson, Kenneth J. Miller, II, Pavan Bhat
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Patent number: 7556823Abstract: Silicone adhesive formulations are provided, in which fentanyl particles are suspended in one or more solvated silicone adhesives. The formulations can be used for manufacturing improved, matrix-type transdermal devices for administering fentanyl.Type: GrantFiled: October 28, 2008Date of Patent: July 7, 2009Assignee: Mylan Pharmaceuticals, Inc.Inventors: Kenneth J. Miller, II, Sharad K. Govil, Kuljit Singh Bhatia
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Publication number: 20090142390Abstract: A transdermal drug-containing dosage unit comprises: a backing layer substantially impervious to the drug to be delivered transdermally; a first polymeric adhesive matrix, in contact with the backing layer, having dispersed therein the drug and having a first delivery profile of the drug; a second polymeric adhesive matrix, in contact with said first polymeric adhesive matrix, having dispersed therein the drug and having a second delivery profile of the drug, wherein said second delivery profile is different from said first delivery profile; and a release liner in contact with the second polymeric adhesive matrix. The first polymeric adhesive matrix can release the drug more quickly or more slowly than the second polymeric adhesive matrix. Through the selection of the two matrices, the delivery profile of the drug through the skin can be selectively modified and controlled.Type: ApplicationFiled: November 17, 2008Publication date: June 4, 2009Applicant: Mylan LaboratoriesInventors: Kristin Jackson, Kenneth J. Miller, II