Patents by Inventor Kenneth J. O'Byrne

Kenneth J. O'Byrne has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DETERMINING CANCER RESPONSIVENESS TO TREATMENT
    Publication number: 20210364519
    Abstract: Provided herein are methods of treating a cancer with or predicting the responsiveness of a cancer to an anti-cancer agent which is capable of inhibiting an enzyme that mediates repair of DNA strand breaks, such as PARP, said method including the step of determining an expression level of SASH1. A method of treating a cancer that includes administering a therapeutically effective amount of an agent that increases the expression and/or an activity of SASH1 is also provided. Further provided herein are methods for identifying an agent that modulates the expression and/or an activity of SASH1 for use in the treatment of cancer.
    Type: Application
    Filed: December 21, 2018
    Publication date: November 25, 2021
    Inventors: Joshua T. Burgess, Emma Bolderson, Derek J. Richard, Kenneth J. O'Byrne
  • Coin mechanism and validator improvements
    Patent number: 7926638
    Abstract: Disclosed is a coin acceptor mechanism with a coin pick-up wheel for advancing coins in a radial path.
    Type: Grant
    Filed: September 25, 2008
    Date of Patent: April 19, 2011
    Assignee: Transtoll Pty Ltd
    Inventor: Kenneth J. O'Byrne
  • COIN MECHANISM AND VALIDATOR IMPROVEMENTS
    Publication number: 20100072024
    Abstract: Disclosed is a coin acceptor mechanism with a coin pick-up wheel for advancing coins in a radial path.
    Type: Application
    Filed: September 25, 2008
    Publication date: March 25, 2010
    Inventor: Kenneth J. O'BYRNE