Abstract: In one example in accordance with the present disclosure, a cell preparation system is described. The cell preparation system includes a fluidic channel to transport cells in single file past multiple detection devices. The cell preparation system also includes a series of detection devices. Each detection device includes 1) a constriction to deform a cell found therein and 2) a sensor to measure a state within the constriction. The cell preparation system also includes a controller. The controller analyzes outputs from multiple sensors to 1) verify a single file transport of cells through the system and 2) identify a cell that passes through the fluidic channel.

Abstract: An automated assay system includes a platform and a rotatable coupon removably positioned within or on the platform. The rotatable coupon includes a plurality of discrete tracks, each of the plurality of discrete tracks configured to contain microfluidic volumes. At least one magnet is operatively disposed on the platform, the rotatable coupon, or combinations thereof, and the at least one magnet is configured to generate a magnetic field at a predetermined area of the rotatable coupon. A motor is operatively connected to the rotatable coupon.

Abstract: Various apparatus and methods relating to determining a quantity measurement of fluid ejected by drop-on-demand nozzles and modifying the ejection parameters based upon the quantity measurement.

Abstract: Various apparatus and methods relating to determining a quantity measurement of fluid ejected by drop-on-demand nozzles and modifying the ejection parameters based upon the quantity measurement.

Abstract: An automated assay system includes a platform and a rotatable coupon removably positioned within or on the platform. The rotatable coupon includes a plurality of discrete tracks, each of the plurality of discrete tracks configured to contain microfluidic volumes. At least one magnet is operatively disposed on the platform, the rotatable coupon, or combinations thereof, and the at least one magnet is configured to generate a magnetic field at a predetermined area of the rotatable coupon. A motor is operatively connected to the rotatable coupon.

Abstract: A sensing method includes exposing a nano-transducer having a controlled surface to a sample including at least one species. Adsorption of the species on the nano-transducer is transduced to a measurable signal as a function of time. Desorption of the species from the nano-transducer is also transduced to a measurable signal as a function of time. A residence time of the at least one species adsorbed on the nano-transducer is extracted from the measurable signals. The adsorption and desorption each define an individual measurable event.

Abstract: A method of detecting analytes in a microfluidic sample includes introducing at least one type of analyte, at least one type of carrier particle, and a fluid into a mixing chamber of a system. The at least one type of analyte binds to a site on the at least one type of carrier particle to form a microfluidic suspension including at least one analyte-bound particle suspended in the fluid. The at least one analyte-bound particle is separated from the fluid by exposing the suspension to physical forces, magnetic forces, or combinations thereof. A spectrophotometric property of a solution is altered using the at least one analyte-bound particle. The altered spectrophotometric property is measured with an optical detection system.

Abstract: A sensing method includes exposing a nano-transducer having a controlled surface to a sample including at least one species. Adsorption of the species on the nano-transducer is transduced to a measurable signal as a function of time. Desorption of the species from the nano-transducer is also transduced to a measurable signal as a function of time. A residence time of the at least one species adsorbed on the nano-transducer is extracted from the measurable signals. The adsorption and desorption each define an individual measurable event.

Abstract: A method of detecting analytes in a microfluidic sample includes introducing at least one type of analyte, at least one type of carrier particle, and a fluid into a mixing chamber of a system. The at least one type of analyte binds to a site on the at least one type of carrier particle to form a microfluidic suspension including at least one analyte-bound particle suspended in the fluid. The at least one analyte-bound particle is separated from the fluid by exposing the suspension to physical forces, magnetic forces, or combinations thereof. A spectrophotometric property of a solution is altered using the at least one analyte-bound particle. The altered spectrophotometric property is measured with an optical detection system.

Abstract: The present invention is an improved liquid toilet bowl cleanser comprising a fluorosurfactant coating agent, an anionic or non-ionic cleaner and a rheology control agent together with other minor excipients. The flurosurfactant continually adheres to and coats the porcelain surface of the toilet bowl during the active life of the cleanser composition preventing the formation of toilet bowl stains and mineral deposits for a substantial period of time after manual cleaning.

Abstract: A package for containing two automatic toilet bowl cleaners, one containing a bleaching cleaner and the other containing a detergent cleaner and a fragrance or dye susceptible to degradation by the bleaching agent, has separate pouches to separate the solids. The pouches open in concert to allow simultaneous dispensing of the solids. In operation, the water in the toilet cistern and bowl is cleaned both by the detergent and the bleaching agent, and the fragrance or dye is not affected by the bleaching agent.

Abstract: A package for containing two automatic toilet bowl cleaners, one containing a bleaching cleaner and the other containing a detergent cleaner and a fragrance or dye susceptible to degradation by the bleaching agent, has separate pouches to separate the solids. The pouches open in concert to allow simultaneous dispensing of the solids. In operation, the water in the toilet cistern and bowl is cleaned both by the detergent and the bleaching agent, and the fragrance or dye is not affected by the bleaching agent.

Abstract: With the crude instrumentation now in use to continuously monitor the status of the fetus at delivery, the obstetrician and labor room staff not only over-recognize the possibility of fetal distress with the resultant rise in operative deliveries, but at times do not identify fetal distress which may result in preventable fetal neurological harm. The invention, which addresses these two basic problems, comprises a method and apparatus for non-invasive determination of blood oxygen saturation in the fetus. The apparatus includes a multiple frequency light source which is coupled to an optical fiber. The output of the fiber is used to illuminate blood containing tissue of the fetus. In the preferred embodiment, the reflected light is transmitted back to the apparatus where the light intensities are simultaneously detected at multiple frequencies. The resulting spectrum is then analyzed for determination of oxygen saturation.

Abstract: The characteristics of a biological fluid sample having an analyte are determined from a model constructed from plural known biological fluid samples. The model is a function of the concentration of materials in the known fluid samples as a function of absorption of wideband infrared energy. The wideband infrared energy is coupled to the analyte containing sample so there is differential absorption of the infrared energy as a function of the wavelength of the wideband infrared energy incident on the analyte containing sample. The differential absorption causes intensity variations of the infrared energy incident on the analyte containing sample as a function of sample wavelength of the energy, and concentration of the unknown analyte is determined from the thus-derived intensity variations of the infrared energy as a function of wavelength from the model absorption versus wavelength function.

Abstract: A powdered carpet composition comprising a blend of an inorganic salt carrier, an agglomerating agent, a fragrance and a polysiloxane material, said composition exhibiting anti-caking and fragrance retention properties and being in proper form for ready application to and removal from carpets so as to provide deodorizing and freshening effects thereto.