Patents by Inventor Kenneth John Shelly

Kenneth John Shelly has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions for boron delivery to mammalian tissue
    Patent number: 6274116
    Abstract: Boron neutron capture therapy can utilize XyB20H17L where X is an alkali metal, y is 1 to 4, and L is a two electron donor such as NH3, and Na2B10H9NCO, among others. These borane salts may be used free or encapsulated in liposomes. Liposomes may also have embedded within their bilayers carboranes to increase the amount of delivered 10B and/or to increase the tumor specificity of the liposome.
    Type: Grant
    Filed: March 29, 1999
    Date of Patent: August 14, 2001
    Assignee: Reagents of the University of California
    Inventors: M. Frederick Hawthorne, Debra Arlene Feaks, Kenneth John Shelly
  • Liposome compositions for boron neutron capture therapy and methods thereof
    Patent number: 5888473
    Abstract: Boron neutron capture therapy can utilize X.sub.y B.sub.20 H.sub.17 L where X is an alkali metal, y is 1 to 4, and L is a two electron donor such as NH.sub.3, and Na.sub.2 B.sub.10 H.sub.9 NCO, among others. These borane salts may be used free or encapsulated in liposomes. Liposomes may have embedded within their bilayers carboranes to increase the amount of delivered .sup.10 B and/or to increase the tumor specificity of the liposome.
    Type: Grant
    Filed: August 3, 1995
    Date of Patent: March 30, 1999
    Assignee: The Regents of the University of California
    Inventors: M. Frederick Hawthorne, Debra Arliene Feakes, Kenneth John Shelly
  • Compositions for boron neutron capture therapy and methods thereof
    Patent number: 5648532
    Abstract: Boron neutron capture therapy can utilize X.sub.y B.sub.20 H.sub.17 L where X is an alkali metal, y is 1 to 4, and L is a two electron donor such as NH.sub.3, and Na.sub.2 B.sub.10 H.sub.9 NCO, among others. These borane salts may be used free or encapsulated in liposomes. Liposomes may have embedded within their bilayers carboranes to increase the amount of delivered .sup.10 B and/or to increase the tumor specificity of the liposome.
    Type: Grant
    Filed: June 3, 1993
    Date of Patent: July 15, 1997
    Assignee: The Regents of the University of California
    Inventors: M. Frederick Hawthorne, Debra Arliene Feakes, Kenneth John Shelly