Patents by Inventor Kenneth Kaushansky

Kenneth Kaushansky has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8283313
    Abstract: A method of increasing hematopoietic stem cell production is disclosed. The method includes administering a TPO mimetic compound to a subject. Pharmaceutical compositions including a TPO mimetic compound and a pharmaceutically acceptable carrier are also disclosed.
    Type: Grant
    Filed: June 20, 2011
    Date of Patent: October 9, 2012
    Assignee: Janssen Pharmaceutica, NV
    Inventors: Brian R. MacDonald, Kenneth Kaushansky
  • Patent number: 8067367
    Abstract: A method of increasing hematopoietic stem cell production is disclosed. The method includes administering a TPO mimetic compound to a subject. Pharmaceutical compositions including a TPO mimetic compound and a pharmaceutically acceptable carrier are also disclosed.
    Type: Grant
    Filed: September 18, 2003
    Date of Patent: November 29, 2011
    Assignee: Janssen Pharmaceutica, N.V.
    Inventors: Brian R. MacDonald, Kenneth Kaushansky
  • Publication number: 20110288019
    Abstract: A method of increasing hematopoietic stem cell production is disclosed. The method includes administering a TPO mimetic compound to a subject. Pharmaceutical compositions including a TPO mimetic compound and a pharmaceutically acceptable carrier are also disclosed.
    Type: Application
    Filed: June 20, 2011
    Publication date: November 24, 2011
    Applicant: Janssen Pharmaceutica, N.V.
    Inventors: Brian R. MacDonald, Kenneth Kaushansky
  • Publication number: 20050282277
    Abstract: A method of increasing hematopoietic stem cell production is disclosed. The method includes administering a TPO mimetic compound to a subject. Pharmaceutical compositions including a TPO mimetic compound and a pharmaceutically acceptable carrier are also disclosed.
    Type: Application
    Filed: September 18, 2003
    Publication date: December 22, 2005
    Inventors: Brian MacDonald, Kenneth Kaushansky
  • Patent number: 6316254
    Abstract: Methods for stimulating erythropoiesis using the hematopoietic protein thrombopoietin, optionally in combination with erythropoietin, are provided. The methods provided may be used to stimulate erythropoiesis in bone marrow and peripheral blood cells and in vitro and in vivo. In addition, methods for treatment of thrombocytopenia and anemia in patients are disclosed.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: November 13, 2001
    Assignee: University of Washington
    Inventor: Kenneth Kaushansky
  • Patent number: 6099830
    Abstract: Methods for stimulating erythropoiesis using the hematopoietic protein thrombopoietin, optionally in combination with erythropoietin, are provided. The methods provided may be used to stimulate erythropoiesis in bone marrow and peripheral blood cells and in vitro and in vivo. In addition, methods for treatment of thrombocytopenia and anemia in patients are disclosed.
    Type: Grant
    Filed: September 12, 1997
    Date of Patent: August 8, 2000
    Assignees: ZymoGenetics, Inc., University of Washington
    Inventor: Kenneth Kaushansky
  • Patent number: 5989537
    Abstract: Methods for stimulating granulocyte/macrophage lineage cells using thrombopoiet in are provided. The methods provided may be used to stimulate granulocyte/macrophage progenitors and neutrophils in bone marrow and peripheral blood cells and in vitro and in vivo. In addition, methods for treatment of neutropenia in patients are disclosed.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: November 23, 1999
    Assignees: ZymoGenetics, Inc., University of Washington
    Inventors: Richard D. Holly, Si Lok, Donald C. Foster, Frederick S. Hagen, Kenneth Kaushansky, Joseph L. Kuijper, Catherine E. Lofton-Day, Pieter J. Oort
  • Patent number: 5545536
    Abstract: Novel proteins possessing substantially the same biological activity as human GM-CSF, as well as proteins having a higher specific activity than native human GM-CSF, are disclosed. The proteins may (a) be unglycosylated; (b) lack N-linked glycosylation but have O-linked glycosylation; or (c) lack one of the two N-linked carbohydrate chains characteristic of native human GM-CSF. The proteins are produced using recombinant DNA techniques in eucaryotic host cells, such as mammalian, yeast, and filamentous fungal host cells. Pharmaceutical compositions including an effective amount of one of the proteins of the invention and a physiologically acceptable carrier or diluent are also disclosed.
    Type: Grant
    Filed: April 27, 1988
    Date of Patent: August 13, 1996
    Assignees: University of Washington, ZymoGenetics, Inc.
    Inventors: Kenneth Kaushansky, Frederick S. Hagen