Abstract: Systems and methods for automatic planogram generation and optimization are disclosed. In some embodiments, an exemplary method includes: based on recommended assortment information regarding future products to be displayed in a retailer store, determining a plurality of candidate layouts each of which corresponds to a two-dimensional arrangement of the future products; for each candidate layout, computing an objective function based on current product location information, a set of parameters and at least one of: a minimum area ratio, a first unprotected rank, a combined propensity score, or a contiguity score; generating, from the plurality of candidate layouts, an optimal layout that optimizes the objective function; generating a planogram based on the optimal layout for the retailer store; and transmitting the planogram to a computing device associated with the retailer store for placing at least some of the future products in the retailer store according to the planogram.

Abstract: Methods of minimizing detection of unintended signals during array-based processes are provided. Methods include the use of sets of fluidic media that inhibit sources of unintended signals during array-based processes. Also provided are systems containing the sets of fluidic media that are configured to perform the array-based processes provided herein.

Abstract: A crowning grader assembly connects with a machine to grade a road or driveway. The crowning grader assembly has a rear drive mount and a forward drive mount. The grader assembly is configured to be selectively connected to the machine and be pushed forward from the rear drive mount or be connected to the machine and be pulled forward from the forward drive mount. The grader assembly has components that allow the blade of the grader assembly to be moved or set to a desired angle through the use of various actuators to set a desired crowning angle of the blade to impart to the road during operation of the grader assembly.

Abstract: A system computes a timing interval between high-capacity vehicles (HCVs) for each of a plurality of HCV corridors within a geographic region, each respective HCV corridor of the plurality of HCV corridors including a start area. For each respective HCV corridor, the system transmits, via a network communication interface, (i) first data to a first computing device associated with a first HCV, the first data indicating the start area of the respective HCV corridor, and a first start time for the first HCV, and (ii) second data to a second computing device associated with a second HCV, the second data indicating the start area of the respective HCV corridor and a second start time for the second HCV, wherein the first start time for the first HCV and the second start time for the second HCV are based on the computed timing interval for the respective HCV corridor.

Abstract: A system for determining recommended product assortments for a retail environment includes at least one computing device that obtains store layout data, product data and forecast data. The forecast data characterizes projected sales information for the products described in the product data. The computing device also obtains demand transference data characterizing changes in demand for one or more products when a different product is unavailable and obtains product replenishment data characterizing a cost to re-stock products. The computing device also determines a recommended product assortment for the products described in the product data for each store described in the store layout data based on the forecast data, the demand transference data, and the product replenishment data and then displays the recommended product assortment.

Abstract: The present disclosure relates to a binder that specifically binds to an N-terminally modified polypeptide through interaction with a modified N-terminal amino acid. Also provided herein is a method and related kits for treating a polypeptide using or comprising the binder and/or modified cleavase. In some embodiments, also provided herein is a method and related kits for transferring information using a plurality of enzymes, including for performing a ligation, extension, and cleavage reaction with nucleic acid molecules associated with the polypeptide for analysis.

Abstract: A computing system computes a timing interval between high-capacity vehicles (HCVs) for each HCV corridor within a geographic region to control rates of HCVs entering and exiting each of the HCV corridors. For each of the HCV corridors, the computing system schedules a first HCV to provide a transport service along the corridor beginning at a first starting time, transmits first schedule data for the corridor to the first HCV, schedules a second HCV to provide the transport service along the corridor beginning at a second starting time after the first starting time according to the timing interval for the corridor, and transmits second schedule data for the corridor to the second HCV.

Abstract: A system computes a timing interval between high-capacity vehicles (HCVs) for each of a plurality of HCV corridors within a geographic region, each respective HCV corridor of the plurality of HCV corridors including a start area. For each respective HCV corridor, the system transmits, via a network communication interface, (i) first data to a first computing device associated with a first HCV, the first data indicating the start area of the respective HCV corridor, and a first start time for the first HCV, and (ii) second data to a second computing device associated with a second HCV, the second data indicating the start area of the respective HCV corridor and a second start time for the second HCV, wherein the first start time for the first HCV and the second start time for the second HCV are based on the computed timing interval for the respective HCV corridor.

Abstract: A computing system computes a timing interval between high-capacity vehicles (HCVs) for each HCV corridor within a geographic region to control rates of HCVs entering and exiting each of the HCV corridors. For each of the HCV corridors, the computing system schedules a first HCV to provide a transport service along the corridor beginning at a first starting time, transmits first schedule data for the corridor to the first HCV, schedules a second HCV to provide the transport service along the corridor beginning at a second starting time after the first starting time according to the timing interval for the corridor, and transmits second schedule data for the corridor to the second HCV.

Abstract: A computing system can detect high capacity vehicles (HCVs) coming online to provide transport services. The computing system monitors transport demand for HCV corridors throughout a geographic region. Each HCV corridor comprises a plurality of possible rendezvous locations and a plurality of possible routes that can be traveled by individual HCVs through the HCV corridor, as opposed to having fixed routes with fixed stops. The computing system can determine a schedule for each HCV corridor, and monitor supply flow of HCVs traveling through each HCV corridor. Based on (i) the transport demand, (ii) the schedule, and (iii) the supply flow of the HCVs for each of the HCV corridors, the computing system can match the HCV with a specified HCV corridor, and transmit match data indicating a start zone of the matching HCV corridor to the computing device of the HCV.

Abstract: A computing system can assign a transport request to a high capacity vehicle (HCV) corridor of a plurality of HCV corridors, where the HCV corridor is associated with a plurality of possible rendezvous locations and a plurality of possible routes that can be traveled by individual HCVs. The computing system can determine, from the transport request of the requesting user, an optimal pick-up location from the plurality of possible rendezvous locations of the HCV corridor for an HCV to rendezvous with the requesting user.

Abstract: Some embodiments include determining a value of an identified pixel of a plurality of pixels of an image from a detector; determining a noise value based on the value of the identified pixel and the detector; determining a range based on the noise value and the value of the identified pixel; comparing the range and a value of at least one pixel of the pixels other than the identified pixel; and adjusting the value of the identified pixel in response to the comparison.

Abstract: Some embodiments include determining a value of an identified pixel of a plurality of pixels of an image from a detector; determining a noise value based on the value of the identified pixel and the detector; determining a range based on the noise value and the value of the identified pixel; comparing the range and a value of at least one pixel of the pixels other than the identified pixel; and adjusting the value of the identified pixel in response to the comparison

Abstract: An improved method and apparatus is used with a group of bales. The group of bales is gripped with a bale handling apparatus. A flexible strip is positioned around the group of bales. The group of bales is then moved while the group of bales is gripped by the bale handling apparatus and while the flexible strip extends around the group of bales. The flexible strip is positioned relative to the group of bales by a positioning member which is connected with the bale handling apparatus.

Abstract: The invention provides a method of detecting multiple nucleic acid sequences using multiplex substrate elements, each having predetermined sets of independent probes, and using mistures of distinguishably labeled nucleotides.

Abstract: An improved method and apparatus is used with a group of bales. The group of bales is gripped with a bale handling apparatus. A flexible strip is positioned around the group of bales. The group of bales is then moved while the group of bales is gripped by the bale handling apparatus and while the flexible strip extends around the group of bales. The flexible strip is positioned relative to the group of bales by a positioning member which is connected with the bale handling apparatus.

Abstract: An improved method and apparatus is used with a group of bales. The group of bales is gripped with a bale handling apparatus. A flexible strip is positioned around the group of bales. The group of bales is then moved while the group of bales is gripped by the bale handling apparatus and while the flexible strip extends around the group of bales. The flexible strip is positioned relative to the group of bales by a positioning member which is connected with the bale handling apparatus.

Abstract: An improved method and apparatus is used with a group of bales. The group of bales is gripped with a bale handling apparatus. A flexible strip is positioned around the group of bales. The group of bales is then moved while the group of bales is gripped by the bale handling apparatus and while the flexible strip extends around the group of bales. The flexible strip is positioned relative to the group of bales by a positioning member which is connected with the bale handling apparatus.

Abstract: Certain embodiments of the present invention provide a method for detecting an electromagnetic field in an imaging system including emitting an electromagnetic field with an electromagnetic transmitter, sensing an electromagnetic field with an imaging system detector, and reading a field image from the detector based at least in part on the electromagnetic field. The imaging system detector is capable of reading an object image and a field image. The detector may be an amorphous silicon flat panel x-ray detector. The electromagnetic transmitter may be used in surgical navigation. The position of a surgical device, instrument, and/or tool may be determined based in part on the field image. The detector may be coordinated to acquire the field image when the electromagnetic transmitter is emitting an electromagnetic field. The detector may be coordinated to acquire the object image when the electromagnetic transmitter is not emitting an electromagnetic field.

Abstract: Certain embodiments of the present invention provide a method for detecting an electromagnetic field in an imaging system including emitting an electromagnetic field with an electromagnetic transmitter, sensing an electromagnetic field with an imaging system detector, and reading a field image from the detector based at least in part on the electromagnetic field. The imaging system detector is capable of reading an object image and a field image. The detector may be an amorphous silicon flat panel x-ray detector. The electromagnetic transmitter may be used in surgical navigation. The position of a surgical device, instrument, and/or tool may be determined based in part on the field image. The detector may be coordinated to acquire the field image when the electromagnetic transmitter is emitting an electromagnetic field. The detector may be coordinated to acquire the object image when the electromagnetic transmitter is not emitting an electromagnetic field.