Patents by Inventor Kenneth L. Luskey

Kenneth L. Luskey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Rapid Establishment and/or Termination of Substantial Steady-State Drug Delivery
    Publication number: 20130030417
    Abstract: The present invention is directed to treatment methods for a disease or condition, in a subject in need of such treatment, that provide alternatives to treatment by injection that give, relative to treatment by injection, improved treatment outcomes, 100% treatment compliance, reduced side effects, and rapid establishment and/or termination of substantial steady-state drug delivery. The method typically includes providing continuous delivery of a drug from an implanted osmotic delivery device, wherein substantial steady-state delivery of the drug at therapeutic concentrations is typically achieved within about 7 days or less after implantation of the osmotic delivery device in the subject and the substantial steady-state delivery of the drug from the osmotic delivery device is continuous over a period of at least about 3 months. In one embodiment, the present invention is directed to treatment of type 2 diabetes mellitus using incretin mimetics.
    Type: Application
    Filed: October 4, 2012
    Publication date: January 31, 2013
    Applicant: INTARCIA THERAPEUTICS, INC.
    Inventors: Thomas R. Alessi, Kenneth L. Luskey
  • Use of (?)(3-trihalomethylphenoxy)(4-halophenyl) acetic acid derivatives for treatment of type 2 diabetes
    Patent number: 8354448
    Abstract: The present invention provides the use of (?)(3-trihalomethylphenoxy)(4-halophenyl)acetic acid derivatives and compositions in the treatment of insulin resistance, Type 2 diabetes and hyperlipidemia.
    Type: Grant
    Filed: July 16, 2009
    Date of Patent: January 15, 2013
    Assignee: Metabolex, Inc.
    Inventors: Kenneth L. Luskey, Jian Luo
  • Use of (?) (3-trihalomethylphenoxy) (4-halophenyl) acetic acid derivatives for treatment of hyperuricemia
    Patent number: 8329749
    Abstract: The present invention provides the use of (?)(3-trihalomethylphenoxy)(4-halophenyl)acetic acid derivatives and compositions in the treatment of insulin resistance, Type 2 diabetes, hyperlipidemia and hyperuricemia.
    Type: Grant
    Filed: July 16, 2009
    Date of Patent: December 11, 2012
    Assignee: Metabolex, Inc.
    Inventors: Kenneth L. Luskey, Jian Luo
  • Rapid establishment and/or termination of substantial steady-state drug delivery
    Patent number: 8298561
    Abstract: The present invention is directed to treatment methods for a disease or condition, in a subject in need of such treatment, that provide alternatives to treatment by injection that give, relative to treatment by injection, improved treatment outcomes, 100% treatment compliance, reduced side effects, and rapid establishment and/or termination of substantial steady-state drug delivery. The method typically includes providing continuous delivery of a drug from an implanted osmotic delivery device, wherein substantial steady-state delivery of the drug at therapeutic concentrations is typically achieved within about 7 days or less after implantation of the osmotic delivery device in the subject and the substantial steady-state delivery of the drug from the osmotic delivery device is continuous over a period of at least about 3 months. In one embodiment, the present invention is directed to treatment of type 2 diabetes mellitus using incretin mimetics.
    Type: Grant
    Filed: September 21, 2010
    Date of Patent: October 30, 2012
    Assignee: Intarcia Therapeutics, Inc.
    Inventors: Thomas R. Alessi, Kenneth L. Luskey
  • Use of (-) (3-Trihalomethylphenoxy) (4-Halophenyl) Acetic Acid Derivatives for Treatment of Insulin Resistance, Type 2 Diabetes, Hyperlipidemia and Hyperuricemia
    Publication number: 20120225940
    Abstract: The present invention provides the use of (?) (3-trihalomethylphenoxy) (4-halophenyl)acetic acid derivatives and compositions in the treatment of insulin resistance, Type 2 diabetes, hyperlipidemia and hyperuricemia.
    Type: Application
    Filed: March 28, 2012
    Publication date: September 6, 2012
    Inventors: Kenneth L. Luskey, Jian Luo
  • Rapid establishment and/or termination of substantial steady-state drug delivery
    Publication number: 20110076317
    Abstract: The present invention is directed to treatment methods for a disease or condition, in a subject in need of such treatment, that provide alternatives to treatment by injection that give, relative to treatment by injection, improved treatment outcomes, 100% treatment compliance, reduced side effects, and rapid establishment and/or termination of substantial steady-state drug delivery. The method typically includes providing continuous delivery of a drug from an implanted osmotic delivery device, wherein substantial steady-state delivery of the drug at therapeutic concentrations is typically achieved within about 7 days or less after implantation of the osmotic delivery device in the subject and the substantial steady-state delivery of the drug from the osmotic delivery device is continuous over a period of at least about 3 months. In one embodiment, the present invention is directed to treatment of type 2 diabetes mellitus using incretin mimetics.
    Type: Application
    Filed: September 21, 2010
    Publication date: March 31, 2011
    Inventors: Thomas R. Alessi, Kenneth L. Luskey
  • USE OF (-)(3-TRIHALOMETHYLPHENOXY)(4-HALOPHENYL) ACETIC ACID DERIVATIVES FOR TREATMENT OF INSULIN RESISTANCE, TYPE 2 DIABETES AND HYPERLIPIDEMIA
    Publication number: 20100093853
    Abstract: The present invention provides the use of (?)(3-trihalomethylphenoxy)(4-halophenyl)acetic acid derivatives and compositions in the treatment of insulin resistance, Type 2 diabetes and hyperlipidemia.
    Type: Application
    Filed: July 16, 2009
    Publication date: April 15, 2010
    Applicants: Metabolex, Inc., DiaTex, Inc.
    Inventors: KENNETH L. LUSKEY, JIAN LUO
  • USE OF (-) (3-TRIHALOMETHYLPHENOXY) (4-HALOPHENYL) ACETIC ACID DERIVATIVES FOR TREATMENT OF INSULIN RESISTANCE, TYPE 2 DIABETES, HYPERLIPIDEMIA AND HYPERURICEMIA
    Publication number: 20100093855
    Abstract: The present invention provides the use of (?)(3-trihalomethylphenoxy)(4-halophenyl)acetic acid derivatives and compositions in the treatment of insulin resistance, Type 2 diabetes, hyperlipidemia and hyperuricemia.
    Type: Application
    Filed: July 16, 2009
    Publication date: April 15, 2010
    Applicants: Metabolex, Inc., DiaTex, Inc.
    Inventors: Kenneth L. Luskey, Jian Luo
  • Use of (-) (3-trihalomethylphenoxy) (4-halophenyl) acetic acid derivatives for treatment of insulin resistance, type 2 diabetes, hyperlipidemia and hyperuricemia
    Patent number: 7576131
    Abstract: The present invention provides the use of (?) (3-trihalomethylphenoxy) (4-halophenyl) acetic acid derivatives and compositions in the treatment of insulin resistance, Type 2 diabetes, hyperlipidemia and hyperuricemia.
    Type: Grant
    Filed: March 4, 2003
    Date of Patent: August 18, 2009
    Assignees: Metabolex, Inc., DiaTex, Inc.
    Inventors: Kenneth L. Luskey, Jian Luo
  • Use of(-) (3-halomethylphenoxy) (4-halophenyl) acetic acid derivatives for treatment of insulin resistance, type 2 diabetes, hyperlipidemia and hyperuricemia
    Publication number: 20040039053
    Abstract: The present invention provides the use of (−) (3-halomethylphenoxy) (4-halophenyl) acetic acid derivatives and compositions in the treatment of insulin resistance, Type 2 diabetes, hyperlipidemia and hyperuricemia. It further provides (−) (3-halomethylphenoxy) (4-halophenyl) acetic acid derivatives that are useful for the treatment of insulin resistance, Type 2 diabetes, hyperlipidemia and hyperuricemia.
    Type: Application
    Filed: May 27, 2003
    Publication date: February 26, 2004
    Inventors: Kenneth L. Luskey, Jian Luo, Zuchun Zhao
  • Use of (-) (3-trihalomethylphenoxy) (4-halophenyl) acetic acid derivatives for treatment of insulin resistance, Type 2 diabetes, hyperlipidemia and hyperuricemia
    Publication number: 20030220399
    Abstract: The present invention provides the use of (−) (3-trihalomethylphenoxy) (4-halophenyl) acetic acid derivatives and compositions in the treatment of insulin resistance, Type 2 diabetes, hyperlipidemia and hyperuricemia.
    Type: Application
    Filed: March 4, 2003
    Publication date: November 27, 2003
    Applicants: Metabolex, Inc., DiaTex, Inc.
    Inventors: Kenneth L. Luskey, Jian Luo
  • Use of (-) (3-trihalomethylphenoxy) (4-halophenyl) acetic acid derivatives for treatment of insulin resistance, type 2 diabetes and hyperlipidemia
    Patent number: 6646004
    Abstract: The present invention provides the use of (−)(3-trihalomethylphenoxy)(4-halophenyl)acetic acid derivatives and compositions in the treatment of insulin resistance, Type 2 diabetes and hyperlipidemia.
    Type: Grant
    Filed: October 31, 2000
    Date of Patent: November 11, 2003
    Assignees: Metabolex, Inc., DiaTex, Inc.
    Inventors: Kenneth L. Luskey, Jian Luo
  • Use of (?) (3-trihalomethylphenoxy) (4-halophenyl) acetic acid derivatives for treatment of insulin resistance, type 2 diabetes, hyperlipidemia and hyperuricemia
    Patent number: 6624194
    Abstract: The present invention provides the use of (−) (3-trihalomethylphenoxy) (4-halophenyl) acetic acid derivatives and compositions in the treatment of insulin resistance, Type 2 diabetes, hyperlipidemia and hyperuricemia. It further provides (−) (3-trihalomethylphenoxy) (4-halophenyl) acetic acid derivatives that are useful for the treatment of insulin resistance, Type 2 diabetes, hyperlipidemia and hyperuricemia.
    Type: Grant
    Filed: November 28, 2000
    Date of Patent: September 23, 2003
    Assignees: Metabolex, Inc., DiaTex, Inc.
    Inventors: Kenneth L. Luskey, Jian Luo, Zuchun Zhao
  • Use of (-) (3-trihalomethylphenoxy) (4-halophenyl) acetic acid derivatives for treatment of insulin resistance, type 2 diabetes, hyperlipidemia and hyperuricemia
    Patent number: 6613802
    Abstract: The present invention provides the use of (−) (3-trihalomethylphenoxy) (4-halophenyl) acetic acid derivatives and compositions in the treatment of insulin resistance, Type 2 diabetes, hyperlipidemia and hyperuricemia.
    Type: Grant
    Filed: June 2, 2000
    Date of Patent: September 2, 2003
    Assignees: Metabolex, Inc., DiaTex, Inc.
    Inventors: Kenneth L. Luskey, Jian Luo
  • Use of (-) (3-trihalomethylphenoxy) (4-halophenyl) acetic acid derivatives for treatment of insulin resistance, type 2 diabetes and hyperlipidemia
    Patent number: 6262118
    Abstract: The present invention provides the use of (−) (3-trihalomethylphenoxy) (4-halophenyl) acetic acid derivatives and compositions in the treatment of insulin resistance, Type 2 diabetes and hyperlipidemia.
    Type: Grant
    Filed: June 4, 1999
    Date of Patent: July 17, 2001
    Assignee: MetaBolex, Inc.
    Inventors: Kenneth L. Luskey, Jian Luo