Patents by Inventor Kenneth L. Roland

Kenneth L. Roland has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20130122039
    Abstract: Immunogenic compositions imparting dual protection against enterotoxigenic labile toxin (LT)-expressing Escherichia coli (ETEC) and Vibrio cholerae based on the hyperexpression of recombinant cholera toxin B antigen by attenuated, live bacterial vectors derived from Vibrio cholerae are disclosed. The compositions exhibit dual immunogenicity and retain the ability to colonize gastrointestinal mucosa-associated lymphoid tissues.
    Type: Application
    Filed: October 16, 2012
    Publication date: May 16, 2013
    Inventors: Kevin P. Killeen, Kenneth L. Roland, Lawrence J. Thomas
  • Patent number: 8287855
    Abstract: Oral immunogenic compositions imparting dual protection against enterotoxigenic labile toxin (LT)-expressing Escherichia coli (ETEC) and Vibrio cholerae based on the delivery of recombinant cholera toxin B antigen by attenuated, live bacterial vectors derived from Vibrio cholerae are disclosed. The compositions exhibit dual immunogenicity and retain the ability to colonize gastrointestinal mucosa-associated lymphoid tissues.
    Type: Grant
    Filed: April 24, 2008
    Date of Patent: October 16, 2012
    Assignee: Celldex Therapeutics, Inc.
    Inventors: Kevin P. Killeen, Kenneth L. Roland, Lawrence J. Thomas
  • Publication number: 20100129396
    Abstract: Oral immunogenic compositions imparting dual protection against enterotoxigenic labile toxin (LT)-expressing Escherichia coli (ETEC) and Vibrio cholerae based on the delivery of recombinant cholera toxin B antigen by attenuated, live bacterial vectors derived from Vibrio cholerae are disclosed. The compositions exhibit dual immunogenicity and retain the ability to colonize gastrointestinal mucosa-associated lymphoid tissues.
    Type: Application
    Filed: April 24, 2008
    Publication date: May 27, 2010
    Inventors: Kevin P Killeen, Kenneth L. Roland, Lawrence J. Thomas
  • Patent number: 6399074
    Abstract: A vaccine for protecting birds against infection by avian pathogenic gram negative microbes is disclosed. The vaccine is a recombinant Salmonella strain expressing O-antigen of an avian pathogenic gram negative microbe such as an E. coli strain that is pathogenic in poultry. The recombinant Salmonella strain also does not express Salmonella O-antigen. Methods of using the vaccine to immunize birds are also disclosed.
    Type: Grant
    Filed: July 24, 1998
    Date of Patent: June 4, 2002
    Assignee: Megan Health, Inc.
    Inventor: Kenneth L. Roland
  • Patent number: 5373501
    Abstract: A telecommunications network testing and protocol analyzer arrangement including an improved control and port selecting circuitry which may be provided in the form of a board which plugs into a standard IBM or IBM compatible PC, XT, AT expansion bus (8 bits) and allows for the operate, non-operate control of up to 180 port relays while at the same time providing 8 simultaneous control outputs for other circuit and parameter control functions. All outputs are standard TTL level outputs which may be directly utilized as relay drivers. The selector and control board is controlled by software running under standard PC DOS of MS DOS. The control and selector board may be controlled completely from the computer keyboard as well as from a remote IBM or IBM compatible computer.
    Type: Grant
    Filed: July 10, 1992
    Date of Patent: December 13, 1994
    Assignee: C & P of Virginia
    Inventor: Kenneth L. Roland