Patents by Inventor Kenneth L Wilkens

Kenneth L Wilkens has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Contiguous capillary electrospray sources and analytical devices
    Patent number: 7544932
    Abstract: Contiguous capillaries useful for separating and electrospraying a fluid comprising analyte and electrolyte are provided. The contiguous capillaries have spray tips at one end of the capillaries and electrically conductive portions in proximity to the spray tips. Methods for making the contiguous capillaries and their use as electrospray sources are also disclosed. Apparatus and methods for conveying analyte ions from the capillaries into analytical instruments, such as a mass spectrometer, are also disclosed. The disclosed contiguous capillaries may be used to carryout electrophoresis separation and electrospray ionization of analytes. Methods for obtaining the mass spectra of macromolecular analytes at concentrations lower than previously possibly are provided using the apparatus and procedures described herein.
    Type: Grant
    Filed: October 20, 2003
    Date of Patent: June 9, 2009
    Assignee: The United States of America, as represented by the Secretary, of the Department of Health and Human Services
    Inventors: George Janini, Haleem J Issaq, Timothy D Veenstra, Thomas P Conrads, Kenneth L Wilkens