Abstract: Parallel chromatography systems and continuous manufacturing methods are described herein that utilize two or more chromatography column skids having columns operating in parallel with automation controls governing which column to load at a given time.

Abstract: A retrieval device may have a contracted state and an expanded state and may include a sheath defining a longitudinal axis; a first arm, a second arm, and a third arm; a first member extending between a distal end of the first arm and a distal end of the third arm; and a second member extending between a distal end of the second arm and the distal end of the third arm. In the expanded state and from a distal-end view, the first and second members and the distal ends of the first arm, second arm, and third arm may form a V-shape with an open mouth.

Abstract: The invention discloses an implant. The implant may include a first flap and a second flap. The first flap may further include a first portion, a second portion and a transition region. The first portion may be configured to be attached proximate a sacrum. The second portion may be configured to be attached to an anterior vaginal wall. The transition region lies between the first portion and the second portion. The second flap may be fabricated such that a portion of the second flap is configured to be attached to a posterior vaginal wall. The implant may be configured such that a value corresponding to a biomechanical parameter defining a biomechanical attribute of the portion of the first flap attaching to the anterior wall is different from a value of the biomechanical parameter defining the biomechanical attribute of the portion of the second flap attaching to the posterior wall.

Abstract: The invention discloses an implant. The implant may include a first flap and a second flap. The first flap may further include a first portion, a second portion and a transition region. The first portion may be configured to be attached proximate a sacrum. The second portion may be configured to be attached to an anterior vaginal wall. The transition region lies between the first portion and the second portion. The second flap may be fabricated such that a portion of the second flap is configured to be attached to a posterior vaginal wall. The implant may be configured such that a value corresponding to a biomechanical parameter defining a biomechanical attribute of the portion of the first flap attaching to the anterior wall is different from a value of the biomechanical parameter defining the biomechanical attribute of the portion of the second flap attaching to the posterior wall.

Abstract: A medical device includes an elongate member. The elongate member has a first end portion and a second end portion. The second end portion of the elongate member has an upper surface and a lower surface disposed opposite the upper surface. The lower surface has a planar portion. The upper surface has a planar portion and a concave portion.

Abstract: A retrieval device may have a contracted state and an expanded state and may include a sheath defining a longitudinal axis; a first arm, a second arm, and a third arm; a first member extending between a distal end of the first arm and a distal end of the third arm; and a second member extending between a distal end of the second arm and the distal end of the third arm. In the expanded state and from a distal-end view, the first and second members and the distal ends of the first arm, second arm, and third arm may form a V-shape with an open mouth.

Abstract: A retrieval device may have a contracted state and an expanded state and may include a sheath defining a longitudinal axis; a first arm, a second arm, and a third arm; a first member extending between a distal end of the first arm and a distal end of the third arm; and a second member extending between a distal end of the second arm and the distal end of the third arm. In the expanded state and from a distal-end view, the first and second members and the distal ends of the first arm, second arm, and third arm may form a V-shape with an open mouth.

Abstract: According to an example embodiment, an implant assembly may include a first handle, a first elongated member defining a first lumen, and a tissue support member extending through the first lumen of the first elongated member, the tissue support member including a first end and a second end, the first end being attached to the first handle.

Abstract: Some embodiments are directed to medical devices, and methods for making and using the medical devices. An exemplary medical device includes a first elongate member, a second elongate member, and a coupler. The coupler may be configured to removably couple the first elongate member to the second elongate member.

Abstract: A medical device includes an elongate member having a first end portion and a second end portion, an extension member movably coupled to the first end portion of the elongate member and an actuation member disposed on the second end portion of the elongate member and operatively coupled to the extension member to move the extension member from a first position with respect to the first end portion of the elongate member to a second position with respect to the elongate member.

Abstract: In an embodiment, a medical device is a bodily implant and includes an elongate member. The elongate member has an inner edge that defines an opening. At least a portion of the inner edge being treated.

Abstract: According to an example embodiment, a delivery device may include a needle and a pump operatively coupled to the needle, the pump having an expanded configuration and a collapsed configuration, the pump being biased to its expanded configuration such that fluid stored in the pump will exit the pump via the needle in response to pressure being applied to the pump, and in response to the pressure being released from the pump, the pump is configured to receive fluid from outside of the delivery device via the needle.

Abstract: The present invention discloses a medical assembly including an implant, a first sleeve, a second sleeve and an elongate member. The implant has a first portion, a second portion and a mid portion. The first portion of the implant is configured to be enclosed by the first sleeve and the second portion of the implant is configured to be enclosed by the second sleeve. The elongate member is configured to couple the implant with the first sleeve and the second sleeve and is configured to respectively extend from the first portion to the mid portion of the implant and past the mid portion such that the elongate member exits the implant through the mid portion and forms a loop near the mid portion.

Abstract: A retrieval device may have a contracted state and an expanded state and may include a sheath defining a longitudinal axis; a first arm, a second arm, and a third arm; a first member extending between a distal end of the first arm and a distal end of the third arm; and a second member extending between a distal end of the second arm and the distal end of the third arm. In the expanded state and from a distal-end view, the first and second members and the distal ends of the first arm, second arm, and third arm may form a V-shape with an open mouth.

Abstract: A medical device includes an elongate member having a first end portion and a second end portion, an extension member movably coupled to the first end portion of the elongate member and an actuation member disposed on the second end portion of the elongate member and operatively coupled to the extension member to move the extension member from a first position with respect to the first end portion of the elongate member to a second position with respect to the elongate member.

Abstract: Some embodiments are directed to medical devices, and methods for making and using the medical devices. An exemplary medical device includes a first elongate member, a second elongate member, and a coupler. The coupler may be configured to removably couple the first elongate member to the second elongate member.

Abstract: A medical device includes an elongate member. The elongate member has a first end portion and a second end portion. The second end portion of the elongate member has an upper surface and a lower surface disposed opposite the upper surface. The lower surface has a planar portion. The upper surface has a planar portion and a concave portion.

Abstract: In an embodiment, a medical device is a bodily implant and includes an elongate member. The elongate member has an inner edge that defines an opening. At least a portion of the inner edge being treated.

Abstract: The invention discloses an implant. The implant may include a first flap and a second flap. The first flap may further include a first portion, a second portion and a transition region. The first portion may be configured to be attached proximate a sacrum. The second portion may be configured to be attached to an anterior vaginal wall. The transition region lies between the first portion and the second portion. The second flap may be fabricated such that a portion of the second flap is configured to be attached to a posterior vaginal wall. The implant may be configured such that a value corresponding to a biomechanical parameter defining a biomechanical attribute of the portion of the first flap attaching to the anterior wall is different from a value of the biomechanical parameter defining the biomechanical attribute of the portion of the second flap attaching to the posterior wall.

Abstract: According to an example embodiment, an implant assembly may include a first handle, a first elongated member defining a first lumen, and a tissue support member extending through the first lumen of the first elongated member, the tissue support member including a first end and a second end, the first end being attached to the first handle.