Patents by Inventor Kenneth M. Tichauer

Kenneth M. Tichauer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR QUANTITATIVE AND ENHANCED-CONTRAST MOLECULAR MEDICAL IMAGING USING CROSS-MODALITY CORRECTION FOR DIFFERING TRACER KINETICS
    Publication number: 20240081759
    Abstract: An apparatus and method for medical imaging uses a first and second contrast agent, the second agent targeted to a particular tissue type. First images are obtained using the first agent, and second images using the second agent using medical imaging systems. An image processing system is adapted to process the first and second medical images by fitting parameters of a pharmacokinetic model to the first medical images, identifying a nontargeted tissue type, scaling the fitted parameters to best match the nontargeted tissue in the second medical images, executing the pharmacokinetic model to prepare a correction image, and generating corrected medical images by subtracting the correction image from the second medical images.
    Type: Application
    Filed: November 13, 2023
    Publication date: March 14, 2024
    Inventors: Kenneth M. TICHAUER, Scott C. DAVIS, Brian William POGUE
  • Methods for quantitative and enhanced-contrast molecular medical imaging using cross-modality correction for differing tracer kinetics
    Patent number: 11813100
    Abstract: An apparatus and method for medical imaging uses a first and second contrast agent, the second agent targeted to a particular tissue type. First images are obtained using the first agent, and second images using the second agent using medical imaging systems. An image processing system is adapted to process the first and second medical images by fitting parameters of a pharmacokinetic model to the first medical images, identifying a nontargeted tissue type, scaling the fitted parameters to best match the nontargeted tissue in the second medical images, executing the pharmacokinetic model to prepare a correction image, and generating corrected medical images by subtracting the correction image from the second medical images.
    Type: Grant
    Filed: January 9, 2017
    Date of Patent: November 14, 2023
    Assignee: The Trustees of Dartmouth College
    Inventors: Kenneth M. Tichauer, Scott C. Davis, Brian William Pogue
  • Apparatus and method for enhanced early photon detection in optical projection tomography
    Patent number: 10986998
    Abstract: A system and method for optical tomography including illuminating an object with pulsing stimulus light and pulsing the stimulus light at a repetition frequency having a pulse period that is greater than a dead-time of a detector. Coordinating the pulse with the dead-time of the detector allows for higher powered light source and improves early photon detection.
    Type: Grant
    Filed: April 26, 2017
    Date of Patent: April 27, 2021
    Assignee: ILLINOIS INSTITUTE OF TECHNOLOGY
    Inventors: Kenneth M. Tichauer, Jovan G. Brankov, Lagnojita Sinha
  • APPARATUS AND METHOD FOR ENHANCED EARLY PHOTON DETECTION IN OPTICAL PROJECTION TOMOGRAPHY
    Publication number: 20170303789
    Abstract: A system and method for optical tomography including illuminating an object with pulsing stimulus light and pulsing the stimulus light at a repetition frequency having a pulse period that is greater than a dead-time of a detector. Coordinating the pulse with the dead-time of the detector allows for higher powered light source and improves early photon detection.
    Type: Application
    Filed: April 26, 2017
    Publication date: October 26, 2017
    Applicant: ILLINOIS INSTITUTE OF TECHNOLOGY
    Inventors: Kenneth M. Tichauer, Jovan G. Brankov, Lagnojita Sinha
  • METHODS FOR QUANTITATIVE AND ENHANCED-CONTRAST MOLECULAR MEDICAL IMAGING USING CROSS-MODALITY CORRECTION FOR DIFFERING TRACER KINETICS
    Publication number: 20170119330
    Abstract: An apparatus and method for medical imaging uses a first and second contrast agent, the second agent targeted to a particular tissue type. First images are obtained using the first agent, and second images using the second agent using medical imaging systems. An image processing system is adapted to process the first and second medical images by fitting parameters of a pharmacokinetic model to the first medical images, identifying a nontargeted tissue type, scaling the fitted parameters to best match the nontargeted tissue in the second medical images, executing the pharmacokinetic model to prepare a correction image, and generating corrected medical images by subtracting the correction image from the second medical images.
    Type: Application
    Filed: January 9, 2017
    Publication date: May 4, 2017
    Inventors: Kenneth M. TICHAUER, Scott C. DAVIS, Brian William POGUE
  • KINETIC DECONVOLUTION OPTICAL RECONSTRUCTION METHOD
    Publication number: 20150066436
    Abstract: A method of determining dynamic parameters for a plurality of sub-regions within an interrogation region comprises processing optical image data and measurements of a concentration of contrast agent entering each of the sub-regions to determine a flow-scaled impulse residue function for each of the sub-regions, and calculating dynamic parameters for each sub-region from a respective flow-scaled impulse residue function.
    Type: Application
    Filed: March 4, 2013
    Publication date: March 5, 2015
    Inventors: Jonathan Thomas Elliott, Keith St. Lawrence, Mamadou Diop, Ting-Yim Lee, Kenneth M. Tichauer