Abstract: The present invention relates to uses of and methods of treatment with cystathionine. In one embodiment, cystathionine reduces the development of toxin-induced liver and/or kidney disease induced by homocystinuria and/or acute nephropathy. In one embodiment, a cystathionine synthesis inhibitor is administered to increase tumor cell apoptosis and/or increase the efficacy of chemotherapeutic treatment. More particularly, cystathionine can protect cells against toxin-induced cellular apoptosis and/or cystathionine synthesis inhibitors can increase neuroblastoma cell kill rates during chemotherapy.

Abstract: The present invention relates to uses of and methods of treatment with cystathionine. In one embodiment, cystathionine reduces the development of toxin-induced liver and/or kidney disease induced by homocystinuria and/or acute nephropathy. In one embodiment, a cystathionine synthesis inhibitor is administered to increase tumor cell apoptosis and/or increase the efficacy of chemotherapeutic treatment. More particularly, cystathionine can protect cells against toxin-induced cellular apoptosis and/or cystathionine synthesis inhibitors can increase neuroblastoma cell kill rates during chemotherapy.

Abstract: Electrical conductance measurement system including a one-dimensional semiconducting channel, with electrical conductance sensitive to electrostatic fluctuations, in a circuit for measuring channel electrical current. An electrically-conductive element is disposed at a location at which the element is capacitively coupled to the channel; a midpoint of the element aligned with about a midpoint of the channel, and connected to first and second electrically-conductive contact pads that are together in a circuit connected to apply a changing voltage across the element. The electrically-conductive contact pads are laterally spaced from the midpoint of the element by a distance of at least about three times a screening length of the element, given in SI units as (K?0/e2D(EF))1/2, where K is the static dielectric constant, ?0 is the permittivity of free space, e is electron charge, and D(EF) is the density of states at the Fermi energy for the element.

Abstract: Electrical conductance measurement system including a one-dimensional semiconducting channel, with electrical conductance sensitive to electrostatic fluctuations, in a circuit for measuring channel electrical current. An electrically-conductive element is disposed at a location at which the element is capacitively coupled to the channel; a midpoint of the element aligned with about a midpoint of the channel, and connected to first and second electrically-conductive contact pads that are together in a circuit connected to apply a changing voltage across the element. The electrically-conductive contact pads are laterally spaced from the midpoint of the element by a distance of at least about three times a screening length of the element, given in SI units as (K?0/e2D(EF))1/2, where K is the static dielectric constant, ?0 is the permittivity of free space, e is electron charge, and D(EF) is the density of states at the Fermi energy for the element.

Abstract: A system and a method for advanced malware analysis. The method filters incoming messages with a watch-list, the incoming messages including attachments, if an incoming message matches the watch-list, forwards the message to a malware detection engine, strips the attachments from the forwarded message, the one or more attachments including one or more executable files, launches a plurality of sandboxes, executes each of the executable files in the plurality of sandboxes, the sandboxes generating analysis results that may be used to determine whether each executable file is malicious, normalizes the analysis results, evaluates the risk level of the attachments to the forwarded message based on the normalized analysis results of the executable files in the attachments to the forwarded message, and, if the risk level of an attachment to the forwarded message is above a certain level, determines that the forwarded message is malicious and permanently quarantines the forwarded message.

Abstract: A system and a method for advanced malware analysis. The method filters incoming messages with a watch-list, the incoming messages including attachments, if an incoming message matches the watch-list, forwards the message to a malware detection engine, strips the attachments from the forwarded message, the one or more attachments including one or more executable files, launches a plurality of sandboxes, executes each of the executable files in the plurality of sandboxes, the sandboxes generating analysis results that may be used to determine whether each executable file is malicious, normalizes the analysis results, evaluates the risk level of the attachments to the forwarded message based on the normalized analysis results of the executable files in the attachments to the forwarded message, and, if the risk level of an attachment to the forwarded message is above a certain level, determines that the forwarded message is malicious and permanently quarantines the forwarded message.

Abstract: The present invention relates to uses of and methods of treatment with cystathionine. In one embodiment, cystathionine reduces the development of toxin-induced liver and/or kidney disease induced by homocystinuria and/or acute nephropathy. In one embodiment, a cystathionine synthesis inhibitor is administered to increase tumor cell apoptosis and/or increase the efficacy of chemo therapeutic treatment. More particularly, cystathionine can protect cells against toxin-induced cellular apoptosis and/or cystathionine synthesis inhibitors can increase neuroblastoma cell kill rates during chemotherapy.

Abstract: A method of assembling a gas turbine engine is provided. The method includes providing at least one heat exchanger assembly including a heat exchanger and a mixer extending downstream from the heat exchanger. The mixer includes a plurality of windows formed therein. The method also includes coupling the at least one heat exchanger assembly within a bypass duct of the engine such that the at least one heat exchanger assembly is coupled to at least one of an outer engine casing and an inner engine casing of the turbine engine.

Abstract: A method of assembling a gas turbine engine includes providing at least one heat exchanger assembly including a heat exchanger and a lobed mixer extending downstream from the heat exchanger, wherein the mixer includes a plurality of lobes that each define a first chute and at least one second chute that extends between each pair of adjacent spaced-apart lobes, and coupling the at least one heat exchanger assembly within a bypass duct of the engine such that the at least one heat exchanger assembly is coupled to at least one of an outer engine casing and an inner engine casing of the turbine engine.

Abstract: A method of assembling a gas turbine engine is provided. The method includes providing at least one heat exchanger assembly including a heat exchanger and a mixer extending downstream from the heat exchanger. The mixer includes a plurality of windows formed therein. The method also includes coupling the at least one heat exchanger assembly within a bypass duct of the engine such that the at least one heat exchanger assembly is coupled to at least one of an outer engine casing and an inner engine casing of the turbine engine.

Abstract: System (1) provides information articles specifically targeted to particular subject matters. A datastream (2) of information, typically discrete articles is output from the internet (3) and processed in a filter operation (4) to select only those items which are relevant to a particular subject area. The resultant articles are published at a website (5) accessible by users (6) who subscribe to the service. When a user (6) enters the website, his activities while on the website are monitored, particularly by noting the articles that he views, and the inspection time taken for an article. The user's activities are used for determining the rank of displayed articles.

Abstract: A method of assembling a gas turbine engine includes providing at least one heat exchanger assembly including a heat exchanger and a lobed mixer extending downstream from the heat exchanger, wherein the mixer includes a plurality of lobes that each define a first chute and at least one second chute that extends between each pair of adjacent spaced-apart lobes, and coupling the at least one heat exchanger assembly within a bypass duct of the engine such that the at least one heat exchanger assembly is coupled to at least one of an outer engine casing and an inner engine casing of the turbine engine.

Abstract: The present invention provides a system for limiting energy levels across the output of a driver circuitry segment (100). The system provides an output structure (102) adapted to drive an output load (104). A transconductance component (106) is communicatively coupled to the output structure, and adapted to output a transconductance current that is proportional to the voltage across the output structure. A scaling component (108) is communicatively coupled to the output structure, and adapted to output a scaled current that is proportional, by some scaling factor, to the current through the output structure. A qualifying component (110) is communicatively coupled to the scaling component, and adapted to activate a trigger component (112) when the scaled current passes a first threshold. The trigger component is communicatively coupled to the qualifying component, the transconductance component, and the output structure.

Abstract: Systems and methods are disclosed to enable determining thermal protection characteristics of an integrated circuit. In one embodiment, an integrated circuit includes a proportional to absolute temperature (PTAT) generator that provides a PTAT signal that varies as a function of temperature. Thermal protection control system provides an output signal indicative of a thermal protection condition based at least in part on the PTAT signal. A monitoring system that provides a path to enable selective measuring of at least one signal associated with operation of the thermal protection control system.

Abstract: A bias device that modifies the bias of a device based on an input signal to the device. The device may have a fixed bias, and the bias device can be connected in parallel with the fixed bias. The device can be an amplifier, such as a linear amplifier or a class AB amplifier. The bias device can be configured to provide maximum bias during the device's crossover time period.

Abstract: The present invention relates generally to a low noise transceiver. The transceiver establishes substantially identical common mode voltages at first and second nodes. A receiver is coupled to the first node for receiving signals. The first and second nodes are connected during a first operating mode to provide a low impedance path for diverting received signals away from the first node and disconnected during a second operating mode to enable the receiver to detect signals received at the first node.

Abstract: A wall mountable holder to dispense the contents of an aerosol can, the holder comprising an outer casing of two parts dimensioned to contain within it a pressurized can, the two parts of said container being pivotally attached at their upper end and having projections to engage the dispensing nozzle of said can so that upon relative movement of said two parts toward each other beyond a predetermined position said means cause movement of said nozzle to thereby release contents from within said can.

Abstract: A hinge mechanism for connecting a surface panel such as a table top to a support frame and operative to guide the panel for pivotal movement about a horizontal axis between a stowed upright attitude adjacent a vertical datum plane and a horizontal operative attitude, the hinge comprising a first link pivoted at a first point to the panel and to the support frame and a second link pivoted to the panel at a point spaced from the first pivot and operatively connected to the first link through a bearing which is slidable in slots, in the first link and in a guide plate, to provide positive triangular guidance and support for the panel, with respect to the frame, in each of the panel's adjusted positions.