Abstract: A simple, highly flexible and scalable platform for making functional complex tissues with heterogeneity and irregularity is provided. The method includes combining undifferentiated cells, such as pluripotent or multipotent stem cells, with a biomaterial to make multiple undifferentiated or naïve subunits, exposing the undifferentiated or naïve subunits to different cell culture environments for induction of differentiation towards different lineages as required by that complex tissue, and combining the then functional subunits with or without the undifferentiated subunits. The differentiated subunits thus combined can be cultured under biological, chemical, and/or physical culture conditions suitable to fine-tune the structural and functional properties of the bioengineered complex tissue to form a bioengineered tissue graft that mimics the structural and functional characteristics of native complex tissue. The bioengineered tissue graft can then used to replace dysfunctional tissue.

Abstract: Devices and methods are provided that simplify and improve placement of stabilizing orthopedic pins, wires, and/or screws in the pelvis in minimally invasive surgery. Provided is a surgical instrument guide containing an adjustable friction clamp for positioning and securing a cannula, and a probe with a blunt, nonpenetrating tip. The probe and a surgical instrument held by the friction clamp are oriented at right angles to one another. In use, the blunt probe is introduced through a small incision and advanced by blunt dissection until the blunt tip is positioned at a desired anatomical landmark on the surface of the pelvis. A cannula inserted through the friction clamp is advanced until the tip of the cannula is within 2 cm of the blunt tip of the probe; an orthopedic pin, wire, and/or screw can then be inserted through the cannula to provide stabilization. The blunt probe may be cannulated.

Abstract: A preparation of silver nanoparticles has been found to be effective in improving functional and behavioral recovery from traumatic spinal cord injury. The silver nanoparticles are provided in a non-flowable gel vehicle, from which they are release at high efficiency, that is applied locally at the site of the spinal cord injury. Silver nanoparticle formulations described herein were found to modify the M1/M2 macrophage phenotype ratio and provides a synergistic effect in the combination with arginase to promote healing processes at the treated injury site, reducing postinjury inflammation.

Abstract: Compositions and methods are provided in which magnesium, copper, zinc, and strontium are provided to enhance osteogenesis, improve bone growth, and/or improve bone density. Magnesium, copper, zinc, and strontium are provided in a defined molar ratio providing synergistic effects that permit the use of small amounts of individual metal species, and without the need for supplemental calcium.

Abstract: Multiple packets are received that were transmitted by multiple mobile electronic device sensors located in a predefined area. The packets each include data detected by the sensors of multiple mobile electronic devices. At least a portion of the collected data is stored including multiple unique device identifiers that belong to multiple mobile electronic devices. Responsive to determining that at least two of the unique device identifiers are sequential, a set of values based on the at least two unique devices identifiers are associated as belonging to a same one of the mobile electronic devices.

Abstract: Multiple packets are received that were transmitted by multiple mobile electronic device sensors located in a predefined area. The packets each include data detected by the sensors of multiple mobile electronic devices. At least a portion of the collected data is stored including multiple unique device identifiers that belong to multiple mobile electronic devices. Responsive to determining that at least two of the unique device identifiers are sequential, a set of values based on the at least two unique devices identifiers are associated as belonging to a same one of the mobile electronic devices.

Abstract: A bioengineered IVD for disc replacement has been developed that has mechanical and structural support characteristics similar to those of native IVD. Extracellular matrix (ECM) provides support to living cell components and interacts with the living cellular components during the fabrication process without introducing toxicity. The composition can be produced from both natural or synthetic source but preferably natural and induced to self-assemble or reconstitute into its solid form under conditions that are mild enough to support cellular survival and growth. The cells induce a volume change of the structures, leading to changes in dimension, ECM density, cell density, mechanical property and stability, etc. The extent of the change in volume of the composition can be precisely controlled by factors such as the density of the ECM, the density of the living cells, the timing for interaction and the serum concentration. Increased structural support is provided by crosslinking.

Abstract: Multiple packets are received that were transmitted by multiple mobile electronic device sensors located in a predefined area. The packets each include data detected by the sensors of multiple mobile electronic devices. At least a portion of the collected data is stored including multiple unique device identifiers that belong to multiple mobile electronic devices. Responsive to determining that at least two of the unique device identifiers are sequential, a set of values based on the at least two unique devices identifiers are associated as belonging to a same one of the mobile electronic devices.

Abstract: A mechanism to connect the supporting portions of orthopaedic implants such as in the head, spine, upper limb and lower limb and thereby prevent loosening and fretting at the implant interface of an orthopaedic implant construct has been developed based on shape memory effect and super-elasticity of shape memory materials such as nickel-titanium (nitinol or NiTi) shape-memory-alloy, without the use of typical threaded fastening technique. Advantages are conferred by making the entire device, not just connecting pieces, out of shape memory alloy and having shape memory effect and super-elasticity. Heating the memory head of the device will compress the connection portion without the use of an auxiliary device (e.g. coupling member) so that the connection portion can be completely clamped down by the memory head.

Abstract: Multiple packets are received that were transmitted by multiple mobile electronic device sensors located in a predefined area. The packets each include data detected by the sensors of multiple mobile electronic devices. At least a portion of the collected data is stored including multiple unique device identifiers that belong to multiple mobile electronic devices. Responsive to determining that at least two of the unique device identifiers are sequential, a set of values based on the at least two unique devices identifiers are associated as belonging to a same one of the mobile electronic devices.

Abstract: A simple, highly flexible and scalable platform for making functional complex tissues with heterogeneity and irregularity is provided. The method includes combining undifferentiated cells, such as pluripotent or multipotent stem cells, with a biomaterial to make multiple undifferentiated or naïve subunits, exposing the undifferentiated or naïve subunits to different cell culture environments for induction of differentiation towards different lineages as required by that complex tissue, and combining the then functional subunits with or without the undifferentiated subunits. The differentiated subunits thus combined can be cultured under biological, chemical, and/or physical culture conditions suitable to fine-tune the structural and functional properties of the bioengineered complex tissue to form a bioengineered tissue graft that mimics the structural and functional characteristics of native complex tissue. The bioengineered tissue graft can then used to replace dysfunctional tissue.

Abstract: An efficient method of compositing planes onto a target surface using a computing device with graphics processing capability is disclosed. The method includes partitioning the target surface, on which planes are composited, into partitions. Each one of the partitions contains connected pixels to be formed by compositing an identical subset of the planes to be composited. Each partition is associated with a corresponding subset of the planes. Each partition and its corresponding set of associated planes are then provided to a graphics processor for composition, using exemplary software components including an application programming interface, a library and device driver software. An image is formed on the target surface by compositing each partition. Using the disclosed method, a single pass through stages of the graphics pipeline for the graphics processor is sufficient to composite multiple planes to form an image on the target surface.

Abstract: Novel hybrid materials and fabrication methods thereof are provided. The novel hybrid materials can include a biodegradable polymer and a biodegradable metallic material. The hybrid material can also include a coupling agent between the biodegradable metallic material and the biodegradable polymer. A method of fabricating a hybrid material can include performing a surface treatment process on the biodegradable metallic material, and then either performing a solvent formation method or a thermal formation method.

Abstract: This invention involves a plasma treated and controllable release antimicrobial peptide coated titanium alloy for surgical implantation, where the alloy with antimicrobial properties is fabricated using surface techniques without adversely compromising its biocompatibility and original mechanical properties. The surface techniques form antimicrobial layers on the alloy capable of resisting microbial adhesion and proliferation, while allowing mammalian cell adhesion and proliferation when the alloy is implanted to human body. In one embodiment, PIII&D is applied to incorporate ions, electrons, free radicals, atoms or molecules on a titanium alloy substrate. A pressurized hydrothermal treatment can be carried out to establish reactive functional groups for antimicrobial purpose or for connecting the substrate and external antimicrobial molecules.

Abstract: The present disclosure discusses methods and apparatus for controlling the video playback in a video playback system. In particular, a method for controlling video playback includes receiving a flip call to display video data from a flip queue buffer. Processing of the video data is then initiated. Flip acknowledgement information is issued in response to receiving the flip call information and prior to completion of the processing of video data to be displayed from the flip queue buffer. By issuing flip acknowledgement information regardless of whether the processing of the video data has been completed, video flip calls can continue to be issued at a constant rate and other processing can continue without waiting, thus resulting in better and smoother video playback and economizing processing resources. Additionally, a decision whether or not to drop a particular video frame is made based on whether a flip queue buffer from a predetermined number of flip queue buffers is available.

Abstract: An efficient method of compositing planes onto a target surface using a computing device with graphics processing capability is disclosed. The method includes partitioning the target surface, on which planes are composited, into partitions. Each one of the partitions contains connected pixels to be formed by compositing an identical subset of the planes to be composited. Each partition is associated with a corresponding subset of the planes. Each partition and its corresponding set of associated planes are then provided to a graphics processor for composition, using exemplary software components including an application programming interface, a library and device driver software. An image is formed on the target surface by compositing each partition. Using the disclosed method, a single pass through stages of the graphics pipeline for the graphics processor is sufficient to composite multiple planes to form an image on the target surface.

Abstract: A method and system for prevention of unauthorized access to multimedia data are disclosed herein. A tamper-resistant system having a software driver, a peripheral device, and a system memory is used to encrypt sensitive routines used by the software driver. The software driver is used to interface between one component of the system, such as a processor, and a peripheral device, such as a graphics chip. The driver incorporates one or more sensitive routines, that if divulged, could possibly allow an unauthorized party access to data processed by the software driver. Accordingly, in one embodiment, the sensitive routines are stored in an encrypted format with the driver. To access a sensitive routine, the driver submits the associated encrypted routine to the peripheral device, as well as a decryption method, if desired, where it is decrypted and stored in a plaintext format in a location, such as system memory, accessible to both the driver and the peripheral device.

Abstract: A video playback circuit receives flip call information and vertical synchronization information, and in response determines a pause mode and a playback mode. Flip call information, as is known in the art, provides an indication for flipping between a front buffer and a back buffer, in order to facilitate rendering into one buffer while rasterizing out of the other buffer. Vertical synchronization information describes the completion of rasterizing an image onto a display, and often occurs at periodic intervals, e.g., 60 Hz, 100 Hz. The video playback circuit further includes a pause/playback-based frame buffer pointer information generator. The pause/playback-based frame buffer pointer information generator generates unfiltered frame buffer pointer information when in the pause mode. Otherwise, the pause/playback-based frame buffer pointer information generator generates filtered frame buffer pointer information when in the playback mode.

Abstract: The present invention relates generally to a shape memory and/or super-elastic material, such as a nickel titanium alloy. Additionally or alternatively, the present invention relates to a super-elastic or pseudo-elastic material that has an initial transition temperature Af above a body temperature. The shape memory material can have a super-elasticity or pseudo-elasticity property at a temperature below the initial transition temperature Af of the material. For example, the shape memory material can have its workable temperature for producing super-elasticity or pseudo-elasticity of about 0° C. to 15° C. below the initial transition temperature Af. The shape memory material can be malleable at a room temperature, and become super-elastic or pseudo-elastic at a body temperature. In addition, the present invention relates to a method of making a shape memory or a super-elastic material.

Abstract: The present invention relates generally to a shape memory and/or super-elastic material, such as a nickel titanium alloy. Additionally or alternatively, the present invention relates to a super-elastic or pseudo-elastic material that has an initial transition temperature Af above a body temperature. The shape memory material can have a super-elasticity or pseudo-elasticity property at a temperature below the initial transition temperature Af of the material. For example, the shape memory material can have its workable temperature for producing super-elasticity or pseudo-elasticity of about 0° C. to 15° C. below the initial transition temperature Af. The shape memory material can be malleable at a room temperature, and become super-elastic or pseudo-elastic at a body temperature. In addition, the present invention relates to a method of making a shape memory or a super-elastic material.