Abstract: The invention relates to compounds of structural formula 1 wherein A is independently N or C—R3, R1 is selected from (C1 to C6) alkyl, (C2 to C6) alkenyl, (C2 to C6) alkynyl, (C3 to C10) cycloalkyl, (C5 to C10) cycloalkenyl, (C2 to C6) heterocycloalkyl, (C6 to C10) aryl, and (C2 to C9) heteroaryl, wherein each of the said (C1 to C6) alkyl, (C2 to C6) alkenyl, (C2 to C6) alkynyl, (C3 to C10) cycloalkyl, (C5 to C10) cycloalkenyl, (C2 to C9) heterocycloalkyl, (C6 to C10) aryl, and (C2 to C9) heteroaryl is optionally substituted with at least one R4 group, and wherein said (C2 to C9) heteroaryl is C-attached, and R2 is selected from the group consisting of

Abstract: The compounds of the invention as shown by general structure I, as shown below, are effective in treating filovirus infections. X is selected from the group consisting of O and H; R1 is selected from (C6 to C10) aryl and (C2 to C9) heteroaryl, and R2 is selected from (C1 to C10) alkyl, (C1 to C10) alkenyl, (C1 to C10) alkynyl, (C3 to C10) cycloalkyl, and (C5 to C10) cycloalkenyl, and NR3aR3b is defined in the specification. These compounds are effective in treating filovirii infections including Ebolavirus and Marburg virus.

Abstract: The invention relates to compounds of structural formula I wherein A, D, and E are independently N or C—R3, G, H, and J are independently N or C, K is N or C—H, L is N, N—R3 or C—R3, and A, D, E, G, H, J, K, and L together cannot have more than 4 N, R1 is selected from (C6 to C10) aryl, (C2 to C9) heteroaryl, and 5-indolyl, wherein each of the said (C6 to C10) aryl and (C2 to C9) heteroaryl is substituted with at least one R4a group, and wherein said (C2 to C9) heteroaryl is C-attached, and R2 is selected from the group consisting of

Abstract: Compounds as exemplified by compound A are useful in the treatment of arenavirus infections and viral infections mediated by arenavirus glycoproteins.

Abstract: The invention relates to compounds of structural formula I wherein A, D, and E are independently N or C—R3, G, H, and J are independently N or C, K is N or C—H, L is N, N—R3 or C—R3, and A, D, E, G, H, J, K, and L together cannot have more than 4 N, R1 is selected from (C6 to C10) aryl, (C2 to C9) heteroaryl, and 5-indolyl, wherein each of the said (C6 to C10) aryl and (C2 to C9) heteroaryl is substituted with at least one R4a group, and wherein said (C2 to C9) heteroaryl is C-attached, and R2 is selected from the group consisting of

Abstract: The compounds of the invention as shown by general structure I, as shown below, are effective in treating filovirus infections. X is selected from the group consisting of O and H; R1 is selected from (C6 to C10) aryl and (C2 to C9) heteroaryl, and R2 is selected from (C1 to C10) alkyl, (C1 to C10) alkenyl, (C1 to C10) alkynyl, (C3 to C10) cycloalkyl, and (C5 to C10) cycloalkenyl, and NR3aR3b is defined in the specification. These compounds are effective in treating filovirii infections including Ebolavirus and Marburg virus.

Abstract: Compounds of structural Formula I were developed for the treatment of infections by filoviruses including Ebolavirus and Marburgvirus, wherein, R1, R2, R3, X and Y are defined in the specification.

Abstract: The invention relates to compounds of structural formula I wherein A, D, and E are independently N or C—R3, G, H, and J are independently N or C, K is N or C—H, L is N, N—R3 or C—R3, and A, D, E, G, H, J, K, and L together cannot have more than 4 N, R1 is selected from (C6 to C10) aryl, (C2 to C9) heteroaryl, and 5-indolyl, wherein each of the said (C6 to C10) aryl and (C2 to C9) heteroaryl is substituted with at least one R4a group, and wherein said (C2 to C9) heteroaryl is C-attached, and R2 is selected from the group consisting of

Abstract: Methods and systems for a video surveillance system are provided. The system includes a plurality of network buses, a plurality of surveillance sensors, control devices, and sensor data storage devices and a keypad controller communicatively coupled to the at least one network bus. The keypad controller includes a plurality of interchangeable control modules communicatively coupled to said keypad controller that matingly engage a complementary portion of said keypad controller. The keypad controller further includes a processor configured to decode codec independent video streams, said processor further comprising a module configured to receive and transmit streaming video data to a network, a synchronous memory interface, and a plurality of universal asynchronous receiver/transmitter (UARTs). The keypad controller also includes a universal serial bus (USB) interface.

Abstract: A method for operating a surveillance system includes performing a first portion of an automated visual surveillance tour of a predetermined control area by inducing movement of at least one visual surveillance camera at a first camera tour speed. The method also includes recording at least one first video image frame of the predetermined control area. The method further includes recording at least one second video image frame of the predetermined control area. The method also includes automatically determining whether a region of interest exists within the predetermined control area. The method further includes performing a second portion of the automated visual surveillance tour by shifting the induced movement of the at least one visual surveillance camera to a second camera tour speed. The method also includes automatically dwelling on the region of interest.

Abstract: Methods and systems for a video surveillance system include a plurality of video cameras, each including a field of view, the cameras are configured to at least one of zoom for changing the camera field of view, tilt for rotating the camera about a horizontal tilt axis, and pan for rotating the camera about a vertical pan axis. The system also includes a processor configured to receive a signal indicative of an image in the field of view of at least one video camera, recognize a target using the received signal, determine a direction to the target from the cameras that recognize the target, and transmit the determined direction to other ones of the plurality of video cameras.

Abstract: A method and a system for video camera assembly are provided. The video camera assembly includes at least one of a pan mechanism rotatable about a pan axis and a tilt mechanism rotatable about a tilt axis. The pan mechanism includes a pan motor and a pan position encoder. The tilt mechanism includes a tilt motor and a tilt position encoder. A controller is communicatively coupled to at least one of the pan mechanism and the tilt mechanism and is configured to apply a filter to a power drive signal of at least one of the pan motor and the tilt motor based on a determined corresponding rotational speed of the at least one of the pan motor and the tilt motor with the effect of reducing steady state vibrations which degrade the visual and audible qualities of said video camera assembly.

Abstract: A method for operating a video system includes performing a visual surveillance tour of a predetermined control area with a pan/tilt/zoom (PTZ) camera. The method also includes recording at least one video image frame of the predetermined control area. The method further includes recording at least one coordinate value associated with a predetermined coordinate system. The method also includes transmitting each of the at least one video image frame and the at least one coordinate value to at least one storage device. The method further includes indexing the at least one video image frame as a function of the at least one coordinate value. The method also includes retrieving the at least one video image frame based on the at least one coordinate value and displaying the at least one video image frame on at least one video display device.

Abstract: The present invention is directed to a chimp sodium channel alpha subunit and methods and compositions for making and using the same.

Abstract: A method for operating a surveillance system includes performing a first portion of an automated visual surveillance tour of a predetermined control area by inducing movement of at least one visual surveillance camera at a first camera tour speed. The method also includes recording at least one first video image frame of the predetermined control area. The method further includes recording at least one second video image frame of the predetermined control area. The method also includes automatically determining whether a region of interest exists within the predetermined control area. The method further includes performing a second portion of the automated visual surveillance tour by shifting the induced movement of the at least one visual surveillance camera to a second camera tour speed. The method also includes automatically dwelling on the region of interest.

Abstract: A method and system for video camera assembly are provided. The video camera assembly includes at least one of a pan mechanism rotatable about a pan axis and a tilt mechanism rotatable about a tilt axis. The video camera assembly further includes an accelerometer coupled to the at least one of the pan mechanism and the tilt mechanism and a controller communicatively coupled to the at least one of the pan motor and the tilt motor, the controller further communicatively coupled to the accelerometer, and the video camera. The controller is configured to receive acceleration data from the accelerometer, determine an oscillatory displacement of the video camera using the received acceleration data, generate a motor angular modulation signal, and apply the motor angular modulation signal to at least one of the pan motor and the tilt motor to reduce the oscillatory displacement of the video camera.

Abstract: Embodiments of the disclosed systems and methods establish quantitative and accurate relationships between system features and system objectives. In one embodiment, the systems and methods are particularly suitable to establish the predictive relationships between system fidelity and training objectives. These systems and methods can combine fidelity values defined by end-users, existing theory and research, or objective performance data from experiments. The predictive relationships defined through these methods can feed a model-based decision support tool that helps predict the impact of fidelity on training effectiveness.

Abstract: A method and a system for video camera assembly are provided. The video camera assembly includes at least one of a pan mechanism rotatable about a pan axis and a tilt mechanism rotatable about a tilt axis. The pan mechanism includes a pan motor and a pan position encoder. The tilt mechanism includes a tilt motor and a tilt position encoder. A controller is communicatively coupled to at least one of the pan mechanism and the tilt mechanism and is configured to apply a filter to a power drive signal of at least one of the pan motor and the tilt motor based on a determined corresponding rotational speed of the at least one of the pan motor and the tilt motor with the effect of reducing steady state vibrations which degrade the visual and audible qualities of said video camera assembly.

Abstract: Method and apparatus for a video camera assembly are provided. The video camera assembly includes a pan mechanism rotatable about a pan axis, a video camera mounted on the pan mechanism such that the video camera is rotatable about the pan axis, and a controller communicatively coupled to the pan mechanism and the video camera. The controller is configured to control the rotation of the video camera about the pan axis at a predetermined speed, acquire a plurality of images from the video camera at a predetermined rate, and display the acquired images panoramically.

Abstract: Methods and systems for a video surveillance system are provided. The system includes a plurality of network buses, a plurality of surveillance sensors, control devices, and sensor data storage devices and a keypad controller communicatively coupled to the at least one network bus. The keypad controller includes a plurality of interchangeable control modules communicatively coupled to said keypad controller that matingly engage a complementary portion of said keypad controller. The keypad controller further includes a processor configured to decode codec independent video streams, said processor further comprising a module configured to receive and transmit streaming video data to a network, a synchronous memory interface, and a plurality of universal asynchronous receiver/transmitter (UARTs). The keypad controller also includes a universal serial bus (USB) interface.