Patents by Inventor Kenneth N. Timmis

Kenneth N. Timmis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Probe Compound for Detecting and Isolating Enzymes and Means and Methods Using the Same
    Publication number: 20120231972
    Abstract: The present invention relates to a probe compound that can comprise any substrate or metabolite of an enzymatic reaction in addition to an indicator component, such as, for example, a fluorescence dye, or the like. Moreover, the present invention relates to means for detecting enzymes in form of an array, which comprises any number of probe compounds of the invention which each comprise a different metabolite of interconnected metabolites representing the central pathways in all forms of life. Moreover, the present invention relates to a method for detecting enzymes involving the application of cell extracts or the like to the array of the invention which leads to reproducible enzymatic reactions with the substrates. These specific enzymatic reactions trigger the indicator (e.g. a fluorescence signal) and bind the enzymes to the respective cognate substrates. Moreover, the invention relates to means for isolating enzymes in form of nanoparticles coated with the probe compound of the invention.
    Type: Application
    Filed: March 19, 2010
    Publication date: September 13, 2012
    Inventors: Peter N. Golyshin, Olga V. Golyshina, Kenneth N. Timmis, Tatyana Chernikova, Agnes Waliczek, Manuel Ferrer, Ana Beloqul, Maria E. Guazzaroni, Jose M. Vieltes, Florencio Pazos, Antonio Lopez De Lacey, Victor M. Fernandez
  • Antibiotic and method of production thereof
    Patent number: 7977375
    Abstract: The invention relates to a novel antibiotic from the macrolactin group and a microbial method for production of macrolactins and a novel isolated Bacillus subtilis, of application as the producing strain for the known Macrolactin A and the novel derivative.
    Type: Grant
    Filed: September 21, 2005
    Date of Patent: July 12, 2011
    Assignee: Helmholtz-Zentrum Für Infektionsforschung GmbH
    Inventors: Kenneth N. Timmis, Gabriella Molinari, Rolf Jansen, Magally Romero-Tabarez, Dwi Andreas Santosa
  • Microorganisms and plasmids for 2,4-dichlorophenoxyacetic acid (2,4-D) monooxygenase formation and process for the production of these plasmids and strains
    Patent number: 6153401
    Abstract: The disclosure relates to the production and the use, by genetic engineering, of plasmids and bacterial strains containing, on a short, precisely characterizable DNA segment, the gene tfda or a gene almost identical to tfdA. The novel plasmids and microorganisms are suitable for the production of 2,4-D (2,4-dichlorophenoxyacetic acid)-monooxygenase, and as starting materials for the transfer, by genetic engineering of the 2,4-D-degrading property of this enzyme to various organisms.
    Type: Grant
    Filed: March 10, 1989
    Date of Patent: November 28, 2000
    Assignee: Hoechst Schering AgrEvo GnbH
    Inventors: Wolfgang R. Streber, Kenneth N. Timmis, Meinhart H. Zenk
  • Microorganisms and plasmids for 2,4-dichlorophenoxyacetic acid (2,4-D)monooxygenase formation and process for the production of these plasmids and strains
    Patent number: 6100446
    Abstract: The disclosure relates to the production and the use, by genetic engineering, of plasmids and bacterial strains containing, on a short, precisely characterizable DNA segment, the gene tfdA or a gene almost identical to tfdA.The novel plasmids and microorganisms are suitable for the production of 2,4-D (2,4-dichlorophenoxyacetic acid)-monooxygenase, and as starting materials for the transfer, by genetic engineering of the 2,4-D-degrading property of this enzyme to various organisms.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: August 8, 2000
    Assignee: Hoechst Schering AgrEvo GmbH
    Inventors: Wolfgang R. Streber, Kenneth N. Timmis, Meinhart H. Zenk