Abstract: The application relates to liposomal nanovesicles comprising porphyrin-lipid conjugates within the liposomal lipid bilayer. Said porphyrin-lipid conjugate comprise porphyrins that are modified with a —CH(R1)—O—R2 group and that chelate a metal ion. Such modifications of the porphyrin allow for ordered assembly in the lipid bilayer of the nanovesicles while resulting in a bathochromic shift in the wavelength of light absorbed by the porphyrin chromophore. These nanovesicles can be used for photothermal therapy, photodynamic therapy, photoacoustic imaging and fluorescence imaging. The application also teaches methods for preparing the porphyrin-lipid conjugates and the nanovesicles.

Abstract: There is provided herein a nanovesicle having a bilayer comprising a saturated first phospholipid and no more than about 15 molar % of a second phospholipid covalently conjugated to a J-aggregate forming dye.

Abstract: There is provided herein a nanovesicle having a bilayer comprising a saturated first phospholipid and no more than about 15 molar % of a second phospholipid covalently conjugated to a J-aggregate forming dye.

Abstract: An independent friction joint structure including: at least one plug part having a connection to a device, the device comprising a lamp head; at least one joint part holding the at least one plug part in place, the at least one joint part having at least one holding structure; at least one side part having the ability to generate frictional rotational resistance to keep the at least one plug part in a predetermined position; at least one electrical contact between the at least one side part and the at least one holding structure of the at least one joint part; and at least one screw to fit all the components of the independent friction joint structure together.