Abstract: The present disclosure relates to Meteorin and its use in prevention and/or treatment of nociceptive pain. Acute and chronic nociceptive pain caused by e.g. injuries to the body or inflammation may be treated by administration of Meteorin to the patient.

Abstract: The present disclosure relates to Meteorin and its use in prevention and/or treatment of chemotherapy-induced neuropathic pain. Neuropathic pain arising as a result of treatment with a chemotherapeutic may be treated by administration of Meteorin to the patient. Meteorin may also be used in prophylactic treatment to prevent neuropathic pain from developing as a result of treatment with a chemotherapeutic.

Abstract: The present invention relates to methods for detecting a change in chromosomal structure. These methods employ labeled probes that bind nucleic acids. For example, these probes may be comprised of nucleic acids or nucleic acid analogs and a detectable label.

Abstract: The present invention relates to a method for making bone particles from bone of a variety of sizes and a workpiece forming and holding device for use with the method. The workpiece forming device includes a base and a base frame attached to the surface of the base. An apparatus for forming a solidified mass of bone and immobilization medium is also provided which includes the workpiece forming device and a detachable former member enclosing the base frame. Bone is immersed in an immobilization medium within such workpiece forming device, which is solidified to form a solidified mass of bone and immobilization medium and then subdivided to provide particles of bone in association to with immobilization medium. The immobilization medium may be optionally removed to leave bone particles suitable for use in orthopedic applications including implants.