Patents by Inventor Kenneth Philip Moder

Kenneth Philip Moder has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Echinocandin/carbohydrate complexes
    Patent number: 8022033
    Abstract: A complex of an echinocandin compound with a carbohydrate is described having improved thermal stability and water solubility. A process for making the echinocandin/carbohydrate complex is also described as well as the use of the complex in pharmaceutical formulations and treatments of fungal infections.
    Type: Grant
    Filed: May 21, 2009
    Date of Patent: September 20, 2011
    Assignee: Eli Lilly and Company
    Inventors: Larry Arnold Larew, Nathaniel Milton, James Lawrence Sabatowski, Kenneth Philip Moder
  • Echinocandin pharmaceutical formulations containing micelle-forming surfactants
    Patent number: 7709444
    Abstract: Pharmaceutical formulations are described comprising an echinocandin compound or echinocandin/carbohydrate complex and a pharmaceutically acceptable micelle-forming surfactant in a non-toxic aqueous solvent such that the solubilization of the echinocandin compound is optimized and the ability to freeze-dry the solution is maintained. Both the solution and freeze-dried formulations have increased stability. A bulking agent, tonicity agent buffer and/or a stabilizing agent may optionally be added to the formulations to further enhance the stability of the formulation.
    Type: Grant
    Filed: April 11, 2005
    Date of Patent: May 4, 2010
    Assignee: Pfizer Inc.
    Inventors: Nathaniel Milton, Kenneth Philip Moder, James Lawrence Sabatowski, Stephanie Ann Sweetana
  • ECHINOCANDIN/CARBOHYDRATE COMPLEXES
    Publication number: 20090258820
    Abstract: A complex of an echinocandin compound with a carbohydrate is described having improved thermal stability and water solubility. A process for making the echinocandin/carbohydrate complex is also described as well as the use of the complex in pharmaceutical formulations and treatments of fungal infections.
    Type: Application
    Filed: May 21, 2009
    Publication date: October 15, 2009
    Inventors: LARRY A. LAREW, Nathaniel Milton, James Lawrence Sabatowski, Kenneth Philip Moder
  • Echinocandin/carbohydrate complexes
    Patent number: 7550428
    Abstract: A complex of an echinocandin compound with a carbohydrate is described having improved thermal stability and water solubility. A process for making the echinocandin/carbohydrate complex is also described as well as the use of the complex in pharmaceutical formulations and treatments of fungal infections.
    Type: Grant
    Filed: August 30, 2005
    Date of Patent: June 23, 2009
    Assignee: Eli Lilly and Company
    Inventors: Larry A. Larew, Nathaniel Milton, James Lawrence Sabatowski, Kenneth Philip Moder
  • Process for the asymmetric synthesis of duloxetine
    Patent number: 7538232
    Abstract: This invention provides an improved asymmetric process for the synthesis of duloxetine involving arylation of Compounds of Formula I.
    Type: Grant
    Filed: January 19, 2006
    Date of Patent: May 26, 2009
    Assignee: Eli Lilly and Company
    Inventors: Mark Anthony Butchko, Alain Merschaert, Kenneth Philip Moder
  • Echinocandin/carbohydrate complexes
    Patent number: 7041637
    Abstract: A complex of an echinocandin compound with a carbohydrate is described having improved thermal stability and water solubility. A process for making the echinocandin/carbohydrate complex is also described as well as the use of the complex in pharmaceutical formulations and treatments of fungal infections.
    Type: Grant
    Filed: August 29, 2001
    Date of Patent: May 9, 2006
    Assignee: Eli Lilly and Company
    Inventors: Larry Arnold Larew, Nathaniel Milton, James Lawrence Sabatowski, Kenneth Philip Moder
  • Echinocandin pharmaceutical formulations containing micelle-forming surfactants
    Patent number: 6960564
    Abstract: Pharmaceutical formulations are described comprising an echinocandin compound or echinocandin/carbohydrate complex and a pharmaceutically acceptable micelle-forming surfactant in a non-toxic aqueous solvent such that the solubilization of the echinocandin compound is optimized and the ability to freeze-dry the solution is maintained. Both the solution and freeze-dried formulations have increased stability. A bulking agent, tonicity agent buffer and/or a stabilizing agent may optionally be added to the formulations to further enhance the stability of the formulation.
    Type: Grant
    Filed: August 29, 2001
    Date of Patent: November 1, 2005
    Assignee: Eli Lilly and Company
    Inventors: Nathaniel Milton, Kenneth Philip Moder, James Lawrence Sabatowski, Stephanie Ann Sweetana
  • Echinocandin pharmaceutical formulations containing micelle-forming surfactants
    Publication number: 20030054981
    Abstract: Pharmaceutical formulations are described comprising an echinocandin compound or echinocandin/carbohydrate complex and a pharmaceutically acceptable micelle-forming surfactant in a non-toxic aqueous solvent such that the solubilization of the echinocandin compound is optimized and the ability to freeze-dry the solution is maintained. Both the solution and freeze-dried formulations have increased stability. A bulking agent, tonicity agent buffer and/or a stabilizing agent may optionally be added to the formulations to further enhance the stability of the formulation.
    Type: Application
    Filed: August 29, 2001
    Publication date: March 20, 2003
    Inventors: Nathaniel Milton, Kenneth Philip Moder, James Lawrence Sabatowski, Stephanie Ann Sweetana
  • Echinocandin/carbohydrate complexes
    Publication number: 20020160942
    Abstract: A complex of an echinocandin compound with a carbohydrate is described having improved thermal stability and water solubility. A process for making the echinocandin/carbohydrate complex is also described as well as the use of the complex in pharmaceutical formulations and treatments of fungal infections.
    Type: Application
    Filed: August 29, 2001
    Publication date: October 31, 2002
    Inventors: Larry Arnold Larew, Nathaniel Milton, James Lawrence Sabatowski, Kenneth Philip Moder