Patents by Inventor Kenneth R. Chien

Kenneth R. Chien has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Retinoid suppression of ventricular muscle cell hypertrophy
    Patent number: 6060311
    Abstract: The invention provides a method of suppressing ventricular muscle cell hypertrophy induced by an .alpha..sub.1 -adrenergic agonist or endothelin, by providing an effective amount of a retinoic acid compound.
    Type: Grant
    Filed: March 10, 1998
    Date of Patent: May 9, 2000
    Assignee: The Regents of the University of California
    Inventors: Kenneth R. Chien, Ming Dong Zhou
  • Retinoid suppression of ventricular muscle cell hypertrophy
    Patent number: 5968981
    Abstract: A method of suppressing ventricular muscle cell hypertrophy induced by an .alpha..sub.1 -adrenergic agonist or endothelin, by providing an effective amount of a retinoic acid compound. Also provided are methods for identifying compounds which suppress ventricular muscle cell hypertrophy, compounds which inhibit the retinoic acid suppression of ventricular muscle cell hypertrophy, and therapeutic methods.
    Type: Grant
    Filed: March 10, 1998
    Date of Patent: October 19, 1999
    Assignee: The Regents of the University of California
    Inventors: Kenneth R. Chien, Ming Dong Zhou
  • Retinoid suppression of ventricular muscle cell hypertrophy
    Patent number: 5767155
    Abstract: A method of suppressing ventricular muscle cell hypertrophy induced by an .alpha..sub.1 -adrenergic agonist or endothelin, by providing an effective amount of a retinoic acid compound. Also provided are methods for identifying compounds which suppress ventricular muscle cell hypertrophy, compounds which inhibit the retinoic acid suppression of ventricular muscle cell hypertrophy, and therapeutic methods.
    Type: Grant
    Filed: July 22, 1996
    Date of Patent: June 16, 1998
    Assignee: The Regents of the University of California
    Inventors: Kenneth R. Chien, Ming Dong Zhou