Patents by Inventor Kenneth Rehder

Kenneth Rehder has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SUBSTITUTED HETEROCYCLIC COMPOUNDS
    Publication number: 20090054457
    Abstract: Disclosed are novel substituted heterocyclic derivatives having the structure of Formula I: The compounds are useful for the treatment of various disease states, in particular cardiovascular diseases such as atrial and ventricular arrhythmias, intermittent claudication, Prinzmetal's (variant) angina, stable and unstable angina, exercise induced angina, congestive heart disease, diabetes, and myocardial infarction.
    Type: Application
    Filed: October 27, 2008
    Publication date: February 26, 2009
    Inventors: Elfatih Elzein, Prabha Ibrahim, Venkata Palle, Kenneth Rehder, Jeffery Zablocki
  • Substituted heterocyclic compounds
    Patent number: 7452889
    Abstract: Disclosed are novel substituted heterocyclic derivatives having the structure of Formula I: The compounds are useful for the treatment of various disease states, in particular cardiovascular diseases such as atrial and ventricular arrhythmias, intermittent claudication, Prinzmetal's (variant) angina, stable and unstable angina, exercise induced angina, congestive heart disease, diabetes, and myocardial infarction.
    Type: Grant
    Filed: August 27, 2007
    Date of Patent: November 18, 2008
    Assignee: CV Therapeutics, Inc.
    Inventors: Elfatih Elzein, Prabha Ibrahim, Venkata Palle, Kenneth Rehder, Jeff Zablocki
  • PRENYLATION INHIBITORS CONTAINING DIMETHYLCYCLOBUTANE AND METHODS OF THEIR SYNTHESIS AND USE
    Publication number: 20080119524
    Abstract: The present invention is directed to compounds useful in the treatment of diseases associated with prenylation of proteins and pharmaceutically acceptable salts thereof, to pharmaceutical compositions comprising same, and to methods for inhibiting protein prenylation in an organism using the same.
    Type: Application
    Filed: January 25, 2008
    Publication date: May 22, 2008
    Inventors: Bradley Brown, Kenneth Rehder, Jon-Paul Strachan, Jeron Eaves, Christopher Lowden
  • SUBSTITUTED HETEROCYCLIC COMPOUNDS
    Publication number: 20080032993
    Abstract: Disclosed are novel substituted heterocyclic derivatives having the structure of Formula I: The compounds are useful for the treatment of various disease states, in particular cardiovascular diseases such as atrial and ventricular arrhythmias, intermittent claudication, Prinzmetal's (variant) angina, stable and unstable angina, exercise induced angina, congestive heart disease, diabetes, and myocardial infarction.
    Type: Application
    Filed: August 27, 2007
    Publication date: February 7, 2008
    Inventors: Elfatih Elzein, Prabha Ibrahim, Venkata Palle, Kenneth Rehder, Jeffrey Zablocki
  • Substituted heterocyclic compounds
    Patent number: 7262198
    Abstract: Disclosed are novel substituted heterocyclic derivatives having the structure of Formula I: The compounds are useful for the treatment of various disease states, in particular cardiovascular diseases such as atrial and ventricular arrhythmias, intermittent claudication, Prinzmetal's (variant) angina, stable and unstable angina, exercise induced angina, congestive heart disease, diabetes, and myocardial infarction.
    Type: Grant
    Filed: June 13, 2006
    Date of Patent: August 28, 2007
    Assignee: CV Therapeutics, Inc.
    Inventors: Elfatih Elzein, Prabha Ibrahim, Venkata Palle, Kenneth Rehder, Jeff Zablocki
  • Prenylation Inhibitors and Methods of Their Synthesis and Use
    Publication number: 20070149549
    Abstract: The present invention is directed to compounds useful in the treatment of diseases associated with prenylation of proteins and pharmaceutically acceptable salts thereof, to pharmaceutical compositions comprising same, and to methods for inhibiting protein prenylation in an organism using the same.
    Type: Application
    Filed: January 1, 2007
    Publication date: June 28, 2007
    Inventors: Francine Li, Kenneth Rehder, Michael Campbell, Celeste Viscardi, Jon-Paul Strachan, Zhengming Guo
  • PRENYLATION INHIBITORS AND METHODS OF THEIR SYNTHESIS AND USE
    Publication number: 20070010561
    Abstract: The present invention is directed to compounds useful in the treatment of diseases associated with prenylation of proteins and pharmaceutically acceptable salts thereof, to pharmaceutical compositions comprising same, and to methods for inhibiting protein prenylation in an organism using the same.
    Type: Application
    Filed: July 14, 2006
    Publication date: January 11, 2007
    Inventors: Bradley Brown, Kenneth Rehder
  • Substituted heterocyclic compounds
    Publication number: 20060229317
    Abstract: Disclosed are novel substituted heterocyclic derivatives having the structure of Formula I: The compounds are useful for the treatment of various disease states, in particular cardiovascular diseases such as atrial and ventricular arrhythmias, intermittent claudication, Prinzmetal's (variant) angina, stable and unstable angina, exercise induced angina, congestive heart disease, diabetes, and myocardial infarction.
    Type: Application
    Filed: June 13, 2006
    Publication date: October 12, 2006
    Inventors: Elfatih Elzein, Prabha Ibrahim, Venkata Palle, Kenneth Rehder, Jeffery Zablocki
  • Substituted heterocyclic compounds
    Patent number: 7115610
    Abstract: Disclosed are novel substituted heterocyclic derivatives having the structure of Formula I: The compounds are useful for the treatment of various disease states, in particular cardiovascular diseases such as atrial and ventricular arrhythmias, intermittent claudication, Prinzmetal's (variant) angina, stable and unstable angina, exercise induced angina, congestive heart disease, diabetes, and myocardial infarction.
    Type: Grant
    Filed: December 17, 2004
    Date of Patent: October 3, 2006
    Assignee: CV Therapeutics, Inc.
    Inventors: Elfatih Elzein, Prabha Ibrahim, Venkata Palle, Kenneth Rehder, Jeffrey Zablocki
  • Prenylation inhibitors and methods of their synthesis and use
    Publication number: 20060025454
    Abstract: The present invention is directed to compounds useful in the treatment of diseases associated with prenylation of proteins and pharmaceutically acceptable salts thereof, to pharmaceutical compositions comprising same, and to methods for inhibiting protein prenylation in an organism using the same.
    Type: Application
    Filed: September 27, 2005
    Publication date: February 2, 2006
    Applicant: PPD Discovery, Inc.
    Inventors: Bradley Brown, Kenneth Rehder
  • Substituted heterocyclic compounds
    Publication number: 20050197346
    Abstract: Disclosed are novel substituted heterocyclic derivatives having the structure of Formula I: The compounds are useful for the treatment of various disease states, in particular cardiovascular diseases such as atrial and ventricular arrhythmias, intermittent claudication, Prinzmetal's (variant) angina, stable and unstable angina, exercise induced angina, congestive heart disease, diabetes, and myocardial infarction.
    Type: Application
    Filed: December 17, 2004
    Publication date: September 8, 2005
    Inventors: Elfatih Elzein, Prabha Ibrahim, Venkata Palle, Kenneth Rehder, Jeffery Zablocki
  • Prenylation inhibitors containing dimethylcyclobutane and methods of their synthesis and use
    Publication number: 20050004122
    Abstract: The present invention is directed to compounds useful in the treatment of diseases associated with prenylation of proteins and pharmaceutically acceptable salts thereof, to pharmaceutical compositions comprising same, and to methods for inhibiting protein prenylation in an organism using the same.
    Type: Application
    Filed: August 6, 2003
    Publication date: January 6, 2005
    Inventors: Bradley Brown, Kenneth Rehder, Jon-Paul Strachan, Jeron Eaves, Christopher Lowden
  • Substituted heterocyclic compounds
    Publication number: 20030181352
    Abstract: Disclosed are novel heterocyclic derivatives, useful for the treatment of various disease states, in particular cardiovascular diseases such as atrial and ventricular arrhythmias, intermittent claudication, Prinzmetal's (variant) angina, stable and unstable angina, exercise induced angina, congestive heart disease, and myocardial infarction. The compounds are also useful in the treatment of diabetes, and for increasing HDL plasma levels in mammals.
    Type: Application
    Filed: July 18, 2002
    Publication date: September 25, 2003
    Inventors: Prabha Ibrahim, Kevin Shenk, Elfatih Elzein, Venkata Palle, Jeff Zablocki, Kenneth Rehder