Patents by Inventor Kenneth Rupert

Kenneth Rupert has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Phospholipase C inhibitors for use in treating inflammatory disorders
    Patent number: 7262197
    Abstract: This invention is directed to heterocyclyl-substituted anilino phospholipase C inhibitor compounds useful in treating or ameliorating an inflammatory disorders and/or restenosis of the general formula (I): and enantiomers, diastereomers and pharmaceutically acceptable salts thereof. The present invention is further directed to pharmaceutical compositions comprising the compounds of the present invention and to methods for treating conditions affected by phospholipase modulation.
    Type: Grant
    Filed: March 31, 2004
    Date of Patent: August 28, 2007
    Assignee: Janssen Pharmaceutica, N.V
    Inventors: Bharat Lagu, Kenneth Rupert, Michael Wachter
  • ARYLINDENOPYRIDINES AND ARYLINDENOPYRIMIDINES AND RELATED THERAPEUTIC AND PROPHYLACTIC METHODS
    Publication number: 20070155760
    Abstract: This invention provides novel arylindenopyridines and arylindenopyrimidines of the formula: wherein R1, R2, R3, R4, and X are as defined above, and pharmaceutical compositions comprising same, useful for treating disorders ameliorated by antagonizing adenosine A2a receptors. This invention also provides therapeutic and prophylactic methods using the instant compounds and pharmaceutical compositions.
    Type: Application
    Filed: November 16, 2006
    Publication date: July 5, 2007
    Inventors: Geoffrey Heintzelman, James Bullington, Kenneth Rupert
  • Arylindenopyridines and arylindenopyrimidines and related therapeutic and prophylactic methods
    Publication number: 20050267142
    Abstract: This invention provides novel arylindenopyridines and arylindenopyrimidines of the formula: wherein R1, R2, R3, R4, and X are as defined above, and pharmaceutical compositions comprising same, useful for treating disorders ameliorated by antagonizing adenosine A2a receptors. This invention also provides therapeutic and prophylactic methods using the instant compounds and pharmaceutical compositions.
    Type: Application
    Filed: June 29, 2005
    Publication date: December 1, 2005
    Inventors: Geoffrey Heintzelman, James Bullington, Kenneth Rupert
  • Arylindenopyridines and arylindenopyrimidines and related therapeutic and prophylactic methods
    Publication number: 20050267138
    Abstract: This invention provides novel arylindenopyridines and arylindenopyrimidines of the formula: wherein R1, R2, R3, R4, and X are as defined above, and pharmaceutical compositions comprising same, useful for treating disorders ameliorated by antagonizing adenosine A2a receptors. This invention also provides therapeutic and prophylactic methods using the instant compounds and pharmaceutical compositions.
    Type: Application
    Filed: June 29, 2005
    Publication date: December 1, 2005
    Inventors: Geoffrey Heintzelman, James Bullington, Kenneth Rupert
  • Arylindenopyridines and arylindenopyrimidines and related therapeutic and prophylactic methods
    Publication number: 20050267139
    Abstract: This invention provides methods of treatment using novel arylindenopyridines and arylindenopyrimidines of the formula: wherein R1, R2, R3, R4, and X are as defined above, and pharmaceutical compositions comprising same, useful for treating disorders ameliorated by antagonizing adenosine A2a receptors. This invention also provides therapeutic and prophylactic methods using the instant compounds and pharmaceutical compositions.
    Type: Application
    Filed: June 29, 2005
    Publication date: December 1, 2005
    Inventors: Geoffrey Heintzelman, James Bullington, Kenneth Rupert
  • Arylindenopyridines and arylindenopyrimidines and related therapeutic and prophylactic methods
    Publication number: 20050239810
    Abstract: This invention provides methods of treatment using novel arylindenopyridines and arylindenopyrimidines of the formula: wherein R1, R2, R3, R4, and X are as defined above, and pharmaceutical compositions comprising same, useful for treating disorders ameliorated by antagonizing adenosine A2a receptors. This invention also provides therapeutic and prophylactic methods using the instant compounds and pharmaceutical compositions.
    Type: Application
    Filed: June 29, 2005
    Publication date: October 27, 2005
    Inventors: Geoffrey Heintzelman, James Bullington, Kenneth Rupert
  • Arylindenopyridines and arylindenopyrimidines and related therapeutic and prophylactic methods
    Publication number: 20050239812
    Abstract: This invention provides novel arylindenopyridines and arylindenopyrimidines of the formula: wherein R1, R2, R3, R4, and X are as defined above, and pharmaceutical compositions comprising same, useful for treating disorders ameliorated by antagonizing adenosine A2a receptors. This invention also provides therapeutic and prophylactic methods using the instant compounds and pharmaceutical compositions.
    Type: Application
    Filed: June 29, 2005
    Publication date: October 27, 2005
    Inventors: Geoffrey Heintzelman, James Bullington, Kenneth Rupert
  • Phospholipase C inhibitors for use in treating inflammatory disorders
    Publication number: 20040242639
    Abstract: This invention is directed to heterocyclyl-substituted anilino phospholipase C inhibitor compounds useful in treating or ameliorating an inflammatory disorders and/or restenosis of the general formula (I): 1
    Type: Application
    Filed: March 31, 2004
    Publication date: December 2, 2004
    Inventors: Bharat Lagu, Kenneth Rupert, Michael Wachter
  • Phospholipase C inhibitors for use in treating inflammatory disorders
    Publication number: 20040235855
    Abstract: This invention is directed to heterocyclyl-substituted anilino phospholipase C inhibitor compounds useful in treating or ameliorating an inflammatory disorders and/or restenosis of the general formula (I): 1
    Type: Application
    Filed: March 31, 2004
    Publication date: November 25, 2004
    Inventors: Bharat Lagu, Meng Pan, Kenneth Rupert, Michael Wachter
  • Phospholipase C inhibitors for use in treating inflammatory disorders
    Publication number: 20040235827
    Abstract: This invention is directed to heterocyclyl-substituted anilino phospholipase C inhibitor compounds useful in treating or ameliorating an inflammatory disorders and/or restenosis of the general formula (I): 1
    Type: Application
    Filed: March 31, 2004
    Publication date: November 25, 2004
    Inventors: Bharat Lagu, Kenneth Rupert, Michael Wachter