Patents by Inventor Kenneth Tramposch

Kenneth Tramposch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fatty acid-containing compositions and methods for the treatment of cytokine mediated disorders
    Publication number: 20060052446
    Abstract: Compositions, dietary supplements and medical foods for the treatment of symptoms of inflammatory disorders may include gamma-linolenic acid or dihomogammalinolenic acid, an inhibitor of ?5 desaturase, and optionally stearidonic acid or ??3 arachidonic acid. Preferred formulations may be in the form of a good tasting, preferably milk or fruit based drink, or a dried powder. Compositions reduce inflammation and inhibit increase in serum arachidonic acid associated with gamma-linolenic acid. The compositions of the invention may also be used for the treatment of cytokine mediated disorders in patients in need thereof.
    Type: Application
    Filed: January 31, 2003
    Publication date: March 9, 2006
    Inventors: Floyd Chilton, Marc Surette, Iphigenia Koumenis, Kenneth Tramposch
  • Use of substituted (5,6) dihydronaphthalenyl compounds having retinoid-like activity to prevent or reduce ischemic injury
    Patent number: 6063817
    Abstract: The present invention relates to methods of preventing, or reducing the severity of, an ischemic injury originating in an animal's dermal tissue by applying to the animal a composition comprising a compound of formula I*: ##STR1## or a nontoxic pharmaceutically acceptable salt, physiologically hydrolyzable ester or solvate thereof, in whichX is --O--CO--, --NH--CO--, --CS--NH--, --CO--O--, --CO--NH--, --COS--, --SCO--, --SCH.sub.2 --, --CH.sub.2 --CH.sub.2 --, --CH.dbd.CH--, --C.tbd.C--, --CH.sub.2 --NH--, --COCH.sub.2 --, --NHCS--, --CH.sub.2 S--, --CH.sub.2 O--, --OCH.sub.2 --, --NHCH.sub.2 -- or --CR.sup.5 .dbd.CR.sup.6 --;n is 1 or 0;R.sup.m and R.sup.k are independently hydrogen, halogen, C.sub.1-6 alkyl, hydroxy, C.sub.1-6 alkyloxy or nitro;R.sup.4 is --(CH.sub.2).sub.t --Y.sup.b, C.sub.1-6 alkyl, or C.sub.3-6 cycloalkyl;R.sup.1 is --CO.sub.2 Z, C.sub.1-6 alkyl, CH.sub.2 OH, --CONHR.sup.y, or CHO;R.sup.a and R.sup.b are independently hydrogen or C.sub.1-6 alkyl, or R.sup.a and R.sup.
    Type: Grant
    Filed: February 19, 1998
    Date of Patent: May 16, 2000
    Assignee: Bristol-Myers Squibb Company
    Inventors: Ronald J. Shannon, Karyn A. Monte, Kenneth Tramposch
  • Isoprenoid phospholipase A2 inhibitors and preparations comprising same
    Patent number: 5141959
    Abstract: Compounds of the formula ##STR1## wherein R.sub.1 is CH.dbd.CY--C(CH.sub.3).dbd.CHX wherein X and Y are different and each is of the formula ##STR2## wherein R' and R" independently are H or alkyl of C.sub.1-6 and R.sub.1 includes all possible geometric isomers are demonstrated effective in treating inflammation, both topically and internally. The mechanism appears to be the inhibition of phospholipase A.sub.2 enzymes.
    Type: Grant
    Filed: September 21, 1990
    Date of Patent: August 25, 1992
    Assignee: Bristol-Myers Squibb Company
    Inventors: F. Ivy Carroll, Anita Lewin, Kenneth Tramposch, Stephen A. Steiner