Patents by Inventor Kenneth Trauner

Kenneth Trauner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Acceleration of wound healing by photodynamic therapy
    Patent number: 6107466
    Abstract: Disclosed is a method for accelerating wound healing in a mammal. The method includes identifying an unhealed wound site or partially-healed wound site in a mammal; administering a photosensitizer to the mammal; waiting for a time period wherein the photosensitizer reaches an effective tissue concentration at the wound site; and photoactivating the photosensitizer at the wound site. The dose of photodynamic therapy is selected to stimulate the production of one or more growth factor by cells at the wound site, without causing tissue destruction.
    Type: Grant
    Filed: September 24, 1998
    Date of Patent: August 22, 2000
    Assignee: The General Hospital Corporation
    Inventors: Tayyaba Hasan, Michael R. Hamblin, Kenneth Trauner
  • Photodynamic therapy for the treatment of osteoarthritis
    Patent number: 5942534
    Abstract: A method of treating a patient who has osteoarthritic disease by administering a therapeutic composition containing a photoactivatable compound, or a precursor thereof, and administering light of a photoactivating wavelength that activates the compound.
    Type: Grant
    Filed: October 10, 1997
    Date of Patent: August 24, 1999
    Assignee: The General Hospital Corporation
    Inventors: Kenneth Trauner, Tayyaba Hasan
  • Inhibition of fibrosis by photodynamic therapy
    Patent number: 5913884
    Abstract: Disclosed is a method for modulating wound healing in a mammal. The method includes the steps of: (a) administering a photosensitizer to a mammal that has an unhealed or partially-healed wound; (b) waiting for the photosensitizer to reach an effective tissue concentration at the wound site; (c) photoactivating the photosensitizer by delivering specifically to the wound site light of a effective wavelength and intensity, for an effective length of time. The modulation of wound healing can include hastening healing by administering a low dose of photodynamic therapy. Alternatively, the modulation can include inhibiting fibrosis by administering a high dose of photodynamic therapy. The photosensitizer can be targeted, for example, to macrophages or myofibroblasts. Targeting can be by conjugation to a targeting moiety such as a protein, peptide or microparticle.
    Type: Grant
    Filed: October 31, 1996
    Date of Patent: June 22, 1999
    Assignee: The General Hospital Corporation
    Inventors: Kenneth Trauner, Tayyaba Hasan, Michael R. Hamblin
  • Photodynamic therapy for the destruction of the synovium in the treatment of rheumatoid arthritis and the inflammatory arthritides
    Patent number: 5368841
    Abstract: A method of treating proliferative diseases of the synovial joint using photodynamic therapy. In particular the method of the invention may be used to destroy synovial tissue in inflammatory joint conditions associated with diseases such as rheumatoid arthritis, lupus erythematosus and other rheumatoid variants. A number of methods of delivery are provided, some of which are non invasive.
    Type: Grant
    Filed: February 11, 1993
    Date of Patent: November 29, 1994
    Assignee: The General Hospital Corporation
    Inventors: Kenneth Trauner, Tayyaba Hasan