Abstract: A vertical stand-up pouch, flat bottom bag, or flexible package, and method for manufacturing same, constructed by modification to existing vertical form and fill packaging machines. The invention involves producing a vertical stand-up pouch or flat bottom bag from a single sheet of packaging film by forming one or two vertical creases along opposing sides of the packaging film tube prior to forming a transverse seal on the tube. The vertical crease is formed using a pivoting tucker mechanism positioned outside the packaging film tube and between two forming plates positioned inside the packaging film tube. A novel method is also disclosed for adjusting the orientation of labeling on the packaging film, which results in the production of innovative packages.

Abstract: A device for insertion into a space between adjacent processes of vertebrae comprising a flexible enclosure which can be placed in a collapsed form prior to insertion between adjacent processes of vertebrae and subsequently placed in an expanded form by injection of a settable resin under pressure, wherein surfaces of the device facing the adjacent processes of vertebrae are closer together in said collapsed form and further apart in said expanded form.

Abstract: The invention discloses the Moraxella catarrhalis outer membrane protein-106 (OMP106) polypeptide, polypeptides derived therefrom (OMP106-derived polypeptides), nucleotide sequences encoding OMP106 polypeptides, and antibodies that specifically bind the OMP106 polypeptide and/or OMP106-derived polypeptides. Also disclosed are immunogenic, prophylactic or therapeutic compositions, including vaccines, comprising OMP106 polypeptide and/or OMP106-derived polypeptides. The invention additionally discloses methods of inducing immune responses to M. catarrhalis and M. catarrhalis OMP106 polypeptides and OMP106-derived polypeptides in animals.

Abstract: A vertical stand-up pouch, flat bottom bag, or flexible package, and method for manufacturing same, constructed by modification to existing vertical form and fill packaging machines. The invention involves producing a vertical stand-up pouch or flat bottom bag from a single sheet of packaging film by forming one or two vertical creases along opposing sides of the packaging film tube prior to forming a transverse seal on the tube. The vertical crease is formed using a pivoting tucker mechanism positioned outside the packaging film tube and between two forming plates positioned inside the packaging film tube. A novel method is also disclosed for adjusting the orientation of labeling on the packaging film, which results in the production of innovative packages.

Abstract: A product and method for producing a string of individual sealed, filled packages separated by perforations. A string of separate packages optionally may be enclosed in a cardboard or other container designed to sit in a pantry or other location for dispensing of individual units. Perforations in the packaging film between separate packages provide a tear point to aid in separating one package from the next. There are several advantages to this format including easy placement of the string of packages into a carton for shipping or dispensing, and the ability to hang a string of packages in locations without the need to attach the packages to a backing strip. The perforations between packages facilitate the packaging and transportation of the entire string or bandolier, and facilitate the removal and use of a separate package.

Abstract: A product and method for producing a string of individual sealed, filled packages separated by perforations. A string of separate packages optionally may be enclosed in a cardboard or other container designed to sit in a pantry or other location for dispensing of individual units. Perforations in the packaging film between separate packages provide a tear point to aid in separating one package from the next. There are several advantages to this format including easy placement of the string of packages into a carton for shipping or dispensing, and the ability to hang a string of packages in locations without the need to attach the packages to a backing strip. The perforations between packages facilitate the packaging and transportation of the entire string or bandolier, and facilitate the removal and use of a separate package.

Abstract: A quick change module operable for being removably attached to and extending below a forming tube of a conventional vertical form, fill, and seal machine to produce a wide assortment of differently sized vertical stand-up pouches or gusseted flat bottom bags. The quick change module comprises at least one pair of adjustable forming plates located below the forming tube. The lateral distance between each pair of forming plates can be adjusted by shifting the position of each forming plate along a corresponding slotted bracket. A gusseting mechanism mounted to the frame of the machine can be positioned between each pair of forming plates imparting a vertical crease along the length of the bag while it is being formed and advanced down the forming tube of the machine.

Abstract: The invention discloses the Moraxella catarrhalis outer membrane protein polypeptide and polypeptides derived therefrom (collectively “OMP21”), nucleotide sequences encoding said OMP21, and antibodies that specifically bind OMP21. Also disclosed are pharmaceutical compositions including prophylactic or therapeutic compositions, which may be immunogenic compositions including vaccines, comprising OMP21, antibodies thereto or nucleotides encoding same. The invention additionally discloses methods of inducing an immune response to M. catarrhalis and OMP21 in an animal, preferably a human, methods of treating and methods of diagnosing Moraxella infections in an animal, preferably a human, and kits therefor.

Abstract: A method for making a multi-compartment microwavable package having one or more open or closed compartments within the package, and method and apparatus for manufacturing the same, constructed by modification to existing vertical form, fill and seal packaging machines. The invention involves producing a multi-compartment bag having an internal permeable wall between compartments from a single sheet of flexible packaging film. A food product can be placed into the first compartment and steam pack can be placed into the second compartment.

Abstract: A method for making a multi-compartment microwavable package having one or more open or closed compartments within the package, and method and apparatus for manufacturing the same, constructed by modification to existing vertical form, fill and seal packaging machines. The invention involves producing a multi-compartment bag having an internal permeable wall between compartments from a single sheet of flexible packaging film. A food product can be placed into the first compartment and steam pack can be placed into the second compartment.

Abstract: Slitters cut through a first layer of film immediately prior to lamination of the first layer to a second layer of film to form a strip therebetween. The degree of bonding between the first and second layers is adjusted so that the strip can be removed without harming the rest of the film or destroying any barrier properties. The lamination process can utilize extrusion lamination or adhesive lamination to provide a variety of uses: removable coupons, prize disclosures, stickers, and an adhesive re-close strip.

Abstract: The invention discloses the Moraxella catarrhalis outer membrane protein-106 (OMP106) polypeptide, polypeptides derived therefrom (OMP106-derived polypeptides), nucleotide sequences encoding said polypeptides, and antibodies that specifically bind the OMP106 polypeptide and/or OMP106-derived polypeptides. Also disclosed are immunogenic, prophylactic or therapeutic compositions, including vaccines, comprising OMP106 polypeptide and/or OMP106-derived polypeptides. The invention additionally discloses methods of inducing immune responses to M. catarrhalis and M. catarrhalis OMP106 polypeptides and OMP106-derived polypeptides in animals.

Abstract: The invention discloses the Moraxella catarrhalis outer membrane protein-106 (OMP106) polypeptide, polypeptides derived therefrom (OMP106-derived polypeptides), nucleotide sequences encoding said polypeptides, and antibodies that specifically bind the OMP106 polypeptide and/or OMP106-derived polypeptides. Also disclosed are immunogenic, prophylactic or therapeutic compositions, including vaccines, comprising OMP106 polypeptide and/or OMP106-derived polypeptides. The invention additionally discloses methods of inducing immune responses to M. catarrhalis and M. catarrhalis OMP106 polypeptides and OMP106-derived polypeptides in animals.

Abstract: A blister kit includes a plurality of blister inhibiting coverings of different sizes and shapes, a plurality of blister dressing coverings of different sizes and shapes, a set of instructions for when and where to use individual ones of the coverings, and a container for storing the coverings and the set of instructions.

Abstract: The invention discloses the Moraxella catarrhalis outer membrane protein polypeptide and polypeptides derived therefrom (collectively “OMP21”), nucleotide sequences encoding said OMP21, and antibodies that specifically bind OMP21. Also disclosed are pharmaceutical compositions including prophylactic or therapeutic compositions, which may be immunogenic compositions including vaccines, comprising OMP21, antibodies thereto or nucleotides encoding same. The invention additionally discloses methods of inducing an immune response to M. catarrhalis and OMP21 in an animal, preferably a human, methods of treating and methods of diagnosing Moraxella infections in an animal, preferably a human, and kits therefor.

Abstract: A flexible package having an integrated reclose strip, and method for manufacturing same, constructed by modification to existing vertical form and fill packaging machines. The reclose strip comprises a length of tacky two-sided adhesive tape. The apparatus for applying a reclose strip is incorporated into the mechanism which supplies the continuous sheet of packaging material to the vertical form, fill, and seal machine. The invention involves producing a pillow pouch or vertical stand-up pouch having an integrated reclose strip from a single sheet of packaging film. In one aspect, the reclose strip comprises a release liner on one side after package formation. In one aspect, the reclose strip comprises no release liner and is attached along the longitudinal axis of the sheet of packaging material such that the reclose strip is disposed in a channel or recess in the fill tube. The reclose strip permits the package to be reclosed after initial opening without folding the package.

Abstract: A quick change module operable for being removably attached to and extending below a forming tube of a conventional vertical form, fill, and seal machine to produce a wide assortment of differently sized vertical stand-up pouches or gusseted flat bottom bags. The quick change module comprises at least one pair of adjustable forming plates located below the forming tube. The lateral distance between each pair of forming plates can be adjusted by shifting the position of each forming plate along a corresponding slotted bracket. A gusseting mechanism mounted to the frame of the machine can be positioned between each pair of forming plates imparting a vertical crease along the length of the bag while it is being formed and advanced down the forming tube of the machine.

Abstract: A stationary tucker bar mechanism attached to a vertical form, fill, and seal packaging machine used to construct a vertical stand-up pouch and a gusseted flat bottom bag. The invention involves producing a vertical stand-up pouch or flat bottom bag from a single sheet of packaging film by forming one or two vertical creases along opposing sides of the packaging film tube prior to forming a transverse seal on the tube. The vertical crease is formed using the stationary tucker bar gusseting mechanism positioned outside the packaging film tube and positioned between two forming plates located inside the packaging film tube. While the tucker bar gusseting mechanism is stationary during operation, it is fully adjustable along multiple axes of orientation.

Abstract: A vertical stand-up pouch, or flexible package having a zipper seal mechanism incorporated therein, and method for manufacturing same, constructed with a quick change module modification to existing vertical form and fill packaging machines. The invention involves producing a vertical stand-up pouch from a single sheet of packaging film by inserting a zipper seal mechanism on a first side of the packaging film tube and creating a vertical crease along the tube prior to forming a transverse seal on the tube. The zipper seal mechanism is attached to the packaging film prior to sealing the sheet of the packaging film along its longitudinal seam forming a tube comprising, in part, a quick change module that easily installs on the base of a forming tube. Likewise, the crease is formed using fixed or stationary modifications to prior art vertical form, fill, and seal machines comprising, in part, a quick change module that easily installs on the base of a forming tube.

Abstract: The invention discloses the Moraxella catarrhalis outer membrane protein-106 (OMP106) polypeptide, polypeptides derived therefrom (OMP106-derived polypeptides), nucleotide sequences encoding OMP106 polypeptides, and antibodies that specifically bind the OMP106 polypeptide and/or OMP106-derived polypeptides. Also disclosed are immunogenic, prophylactic or therapeutic compositions, including vaccines, comprising OMP106 polypeptide and/or OMP106-derived polypeptides. The invention additionally discloses methods of inducing immune responses to M. catarrhalis and M. catarrhalis OMP106 polypeptides and OMP106-derived polypeptides in animals.