Patents by Inventor Kenneth WENGLER

Kenneth WENGLER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NEUROMELANIN-SENSITIVE MRI AND METHODS OF USE THEREOF
    Publication number: 20230389854
    Abstract: A neuromelanin sensitive magnetic resonance imaging (“MRI”) technique, method and computer-accessible medium for measuring the extent of, providing a diagnosis of, monitoring the treatment of, assessing novel treatments for, or determining a prognosis related to one or more neurological conditions.
    Type: Application
    Filed: May 15, 2023
    Publication date: December 7, 2023
    Inventors: Samuel CLARK, Clifford Mills CASSIDY, Pedro ROSA-NETO, Kenneth WENGLER, Guillermo HORGA HERNANDEZ
  • USE OF NEUROMELANIN-SENSITIVE MRI AS A BIOMARKER OF DOPAMINE FUNCTION
    Publication number: 20230200716
    Abstract: The subject matter disclosed herein relates to a method for determining dopamine function in a subject, the method comprising acquiring one or more neuromelanin-Magnetic Resonance Imaging (NM-MRI) scans of the subject's dopamine-associated brain region of interest.
    Type: Application
    Filed: February 17, 2023
    Publication date: June 29, 2023
    Inventors: Guillermo Horga HERNANDEZ, Clifford Mills CASSIDY, Kenneth WENGLER
  • SYSTEMS, DEVICES, AND METHODS FOR HARMONIZATION OF IMAGING DATASETS INCLUDING BIOMARKERS
    Publication number: 20220292657
    Abstract: An exemplary system, method and computer-accessible medium for harmonizing neuromelanin (NM) data using combat directly on a NM database or using combat generated coefficients to harmonize future data can include, for example, receiving imaging information of a brain of the patient(s), from one MRI scanner, receiving imaging information of a brain of the patient(s), from a second MRI scanner and using combat to harmonize the data between scanners against a reference dataset. The Neuromelanin (NM) concentration of the patient(s) can then be determined based on the harmonized data. The NM concentration can be determined using a voxel-wise analysis procedure. The voxel-wise analysis procedure can be used to determine a topographical pattern(s) within a substantia nigra (SN) of the brain of the patient(s).
    Type: Application
    Filed: March 11, 2022
    Publication date: September 15, 2022
    Applicants: TERRAN BIOSCIENCES, INC., THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, THE RESEARCH FOUNDATION FOR MENTAL HEALTH HYGIENE, INC.
    Inventors: Samuel CLARK, Kenneth WENGLER, Guillermo HORGA HERNANDEZ
  • NEUROMELANIN-SENSITIVE MRI FOR ASSESSING PARKINSON'S DISEASE
    Publication number: 20220273184
    Abstract: A neuromelanin sensitive magnetic resonance imaging (“MRI”) technique, method and computer-accessible medium for measuring the extent of, providing a diagnosis of, monitoring the treatment of, assessing novel treatments for, or determining a prognosis related to Parkinson's disease.
    Type: Application
    Filed: August 17, 2020
    Publication date: September 1, 2022
    Inventors: Samuel CLARK, Guillermo HORGA HERNANDEZ, Clifford Mills CASSIDY, Kenneth WENGLER