Patents by Inventor Kenneth Wiggall

Kenneth Wiggall has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Prolyl hydroxylase inhibitors
    Patent number: 8324208
    Abstract: The invention described herein relates to certain pyrimidinetrione N-substituted glycine derivatives of formula (I) which are antagonists of HIF prolyl hydroxylases and are useful for treating diseases benefiting from the inhibition of this enzyme, anemia being one example.
    Type: Grant
    Filed: June 22, 2007
    Date of Patent: December 4, 2012
    Assignee: GlaxoSmithKline LLC
    Inventors: Kevin J. Duffy, Duke M. Fitch, Jian Jin, Ronggang Liu, Antony N. Shaw, Kenneth Wiggall
  • PROLYL HYDROXYLASE INHIBITORS
    Publication number: 20100113444
    Abstract: The invention described herein relates to certain pyrimidinetrione N-substituted glycine derivatives of formula (I), (I) which are antagonists of HIF prolyl hydroxylases and are useful for treating diseases benefiting from the inhibition of this enzyme, anemia being one example.
    Type: Application
    Filed: June 22, 2007
    Publication date: May 6, 2010
    Inventors: Kevin J. Duffy, Duke M. Fitch, Jian Jin, Ronggang Liu, Antony N. Shaw, Kenneth Wiggall
  • Thrombopoietin mimetics
    Patent number: 7674887
    Abstract: Invented are non-peptide TPO mimetics. Also invented are novel processes and intermediates used in the preparation of the presently invented compounds. Also invented is a method of treating thrombocytopenia, in a mammal, including a human, in need thereof which comprises administering to such mammal an effective amount of a selected hydroxy-1-azobenzene derivative.
    Type: Grant
    Filed: June 18, 2008
    Date of Patent: March 9, 2010
    Assignee: GlaxoSmithKline LLC
    Inventors: Kevin J. Duffy, Juan I. Luengo, Antony N. Shaw, Kenneth Wiggall
  • NOVEL CHEMICAL COMPOUNDS
    Publication number: 20090203692
    Abstract: This invention relates to newly identified compounds for inhibiting hYAK3 proteins and methods for treating diseases associated with hYAK3 activity.
    Type: Application
    Filed: May 18, 2006
    Publication date: August 13, 2009
    Inventors: Kevin Duffy, Deping Chai, Mirela Colon, Duke M. Fitch, Sarah Rae King, Antony N. Shaw, Rosanna Tedesco, Kenneth Wiggall, Neil W. Johnson, Michael N. Zimmerman
  • THROMBOPOIETIN MIMETICS
    Publication number: 20090176746
    Abstract: Invented are non-peptide TPO mimetics. Also invented are novel processes and intermediates used in the preparation of the presently invented compounds. Also invented is a method of treating thrombocytopenia, in a mammal, including a human, in need thereof which comprises administering to such mammal an effective amount of a selected hydroxy-1-azobenzene derivative.
    Type: Application
    Filed: June 18, 2008
    Publication date: July 9, 2009
    Inventors: Kevin J Duffy, Connie Erickson-Miller, Daniel F. Eppley, Julian Jenkins, Juan I. Luengo, Nannan Liu, Alan T. Price, Antony N. Shaw, Sophie Visonneau, Kenneth Wiggall
  • THROMBOPOIETIN MIMETICS
    Publication number: 20090176973
    Abstract: Invented are non-peptide TPO mimetics. Also invented are novel processes and intermediates used in the preparation of the presently invented compounds. Also invented is a method of treating thrombocytopenia, in a mammal, including a human, in need thereof which comprises administering to such mammal an effective amount of a selected hydroxy-1-azobenzene derivative.
    Type: Application
    Filed: June 18, 2008
    Publication date: July 9, 2009
    Inventors: Kevin J. Duffy, Connie Erickson-Miller, Daniel F. Eppley, Julian Jenkins, Juan I. Luengo, Nannan Liu, Alan T. Price, Antony N. Shaw, Sophie Visonneau, Kenneth Wiggall
  • Thrombopoietin mimetics
    Patent number: 7452874
    Abstract: Invented are non-peptide TPO mimetics. Also invented are novel processes and intermediates used in the preparation of the presently invented compounds. Also invented is a method of treating thrombocytopenia, in a mammal, including a human, in need thereof which comprises administering to such mammal an effective amount of a selected hydroxy-1-azobenzene derivative.
    Type: Grant
    Filed: January 8, 2007
    Date of Patent: November 18, 2008
    Assignee: SmithKline Beecham Corp.
    Inventors: Kevin J. Duffy, Juan I. Luengo, Antony N. Shaw, Kenneth Wiggall
  • Thrombopoietin mimetics
    Publication number: 20080214640
    Abstract: Invented are non-peptide TPO mimetics. Also invented are novel processes and intermediates used in the preparation of the presently invented compounds. Also invented is a method of treating thrombocytopenia, in a mammal, including a human, in need thereof which comprises administering to such mammal an effective amount of a selected hydroxy-1-azobenzene derivative.
    Type: Application
    Filed: January 8, 2007
    Publication date: September 4, 2008
    Inventors: Kevin J. Duffy, Connie Erickson-Miller, Daniel F. Eppley, Julian Jenkins, Juan I. Luengo, Nannan Liu, Alan T. Price, Antony N. Shaw, Sophie Visonneau, Kenneth Wiggall
  • Novel Chemical Compounds
    Publication number: 20080214455
    Abstract: This invention relates to newly identified compounds for inhibiting hYAK3 proteins and methods for treating diseases associated with hYAK3 activity.
    Type: Application
    Filed: May 3, 2006
    Publication date: September 4, 2008
    Inventors: Kevin Duffy, Deping Chai, Mirela Colon, Duke M. Fitch, Sarah Rae King, Antony N. Shaw, Rosanna Tedesco, Kenneth Wiggall, Michael N. Zimmerman, Neil W. Johnson, Jiri Kasparec
  • N-Substituted Glycine Derivatives: Prolyl Hydroxylase Inhibitors
    Publication number: 20080171756
    Abstract: The invention described herein relates to certain pyrimidinedione N-substituted glycine derivatives of formula (I) which are antagonists of HIF prolyl hydroxylases and are useful for treating diseases benefiting from the inhibition of this enzyme, anemia being one example.
    Type: Application
    Filed: January 11, 2008
    Publication date: July 17, 2008
    Inventors: Antony N. Shaw, Kevin J. Duffy, Rosanna Tedesco, Kenneth Wiggall
  • Thrombopoietin mimetics
    Publication number: 20080090787
    Abstract: Invented are non-peptide TPO mimetics. Also invented are novel processes and intermediates used in the preparation of the presently invented compounds. Also invented is a method of treating thrombocytopenia, in a mammal, including a human, in need thereof which comprises administering to such mammal an effective amount of a selected hydroxy-1-azobenzene derivative.
    Type: Application
    Filed: January 8, 2007
    Publication date: April 17, 2008
    Inventors: Kevin Duffy, Connie Erickson-Miller, Daniel Eppley, Julian Jenkins, Juan Luengo, Nannan Liu, Alan Price, Antony Shaw, Sophie Visonneau, Kenneth Wiggall
  • Thrombopoietin mimetics
    Publication number: 20080090996
    Abstract: Invented are non-peptide TPO mimetics. Also invented are novel processes and intermediates used in the preparation of the presently invented compounds. Also invented is a method of treating thrombocytopenia, in a mammal, including a human, in need thereof which comprises administering to such mammal an effective amount of a selected hydroxy-1-azobenzene derivative.
    Type: Application
    Filed: January 8, 2007
    Publication date: April 17, 2008
    Inventors: Kevin Duffy, Connie Erickson-Miller, Daniel Eppley, Julian Jenkins, Juan Luengo, Nannan Liu, Alan Price, Antony Shaw, Sophie Visonneau, Kenneth Wiggall
  • Thrombopoietin mimetics
    Patent number: 7332481
    Abstract: Invented are non-peptide TPO mimetics. Also invented are novel processes and intermediates used in the preparation of the presently invented compounds. Also invented is a method of treating thrombocytopenia, in a mammal, including a human, in need thereof which comprises administering to such mammal an effective amount of a selected hydroxy-1-azobenzene derivative.
    Type: Grant
    Filed: January 5, 2007
    Date of Patent: February 19, 2008
    Assignee: SmithKline Beecham Corporation
    Inventors: Kevin J. Duffy, Connie Erickson-Miller, Julian Jenkins, Juan Luengo, Alan T. Price, Antony N. Shaw, Sophie Visonneau, Kenneth Wiggall
  • THROMBOPOIETIN MIMETICS
    Publication number: 20070129338
    Abstract: Invented are non-peptide TPO mimetics. Also invented are novel processes and intermediates used in the preparation of the presently invented compounds. Also invented is a method of treating thrombocytopenia, in a mammal, including a human, in need thereof which comprises administering to such mammal an effective amount of a selected hydroxy-1-azobenzene derivative.
    Type: Application
    Filed: January 5, 2007
    Publication date: June 7, 2007
    Inventors: Kevin DUFFY, Connie Erickson-Miller, Daniel Eppley, Julian Jenkins, Juan Luengo, Nannan Liu, Alan Price, Antony Shaw, Sophie Visonneau, Kenneth Wiggall
  • Thrombopoietin mimetics
    Publication number: 20040019190
    Abstract: Invented are non-peptide TPO mimetics. Also invented are novel processes and intermediates used in the preparation of the presently invented compounds. Also invented is a method of treating thrombocytopenia, in a mammal, including a human, in need thereof which comprises administering to such mammal an effective amount of a selected hydroxy-1-azobenzene derivative.
    Type: Application
    Filed: July 3, 2003
    Publication date: January 29, 2004
    Inventors: Connie J Erickson-Miller, Daniel F. Eppley, Julian Jenkins, Juan I. Luengo, Nannan Liu, Alan T. Price, Anthony N. Shaw, Sophie Visonneau, Kenneth Wiggall