Abstract: A toilet seat covering device for reducing viral transmission includes a sheet, which is shaped substantially complementarily to an upper face of a toilet seat. The sheet comprises resiliently flexible, substantially inelastic, elastomer. The sheet is positionable on the upper face of the toilet seat so the sheet to substantially covers the upper face. The sheet prevents direct contact of the upper face of the toilet seat with a user who is seated upon the toilet seat. The sheet may be one of a plurality of sheets, the sheets of which are sequentially extractable for use, after which they can be disposed of.

Abstract: The present invention relates to neutralizing antibodies of the human pituitary adenylate cyclase activating polypeptide type I receptor (PAC1) and pharmaceutical compositions comprising such antibodies. Methods of treating or preventing headache conditions, such as migraine and cluster headache, using the neutralizing antibodies are also described.

Abstract: An exemplary vascular neural interface device/configuration and method can be provided for at least one of stimulating or recording the nervous system. For example, a package can be provided which can be inserted within a blood vessel. The package can include at least one transducer, at least one electrode, and at least one integrated circuit. The at least one transducer can receive or transmit a wireless signal which is used to provide energy or communicate with the at least one integrated circuit to at least one of record or stimulate the nervous system using recording electronics or stimulating electronics.

Abstract: A microelectronic chip device includes a semiconductor substrate and multiple on-chip strain sensors (OCSSs) constructed on the substrate at various locations of the substrate. The OCSSs may each include multiple piezoresistive devices configured to sense a strain at a location of the various locations and produce a strain signal representing the strain at that location. A strain measurement circuit may also be constructed on the semiconductor substrate and configured to measure strain parameters from the strain signals produced by the OCSSs. The strain parameters represent the strains at the various location. Values of the strain parameters can be used for analysis of mechanical stress on the chip device.

Abstract: A cross reality system that provides an immersive user experience by storing persistent spatial information about the physical world that one or multiple user devices can access to determine position within the physical world and that applications can access to specify the position of virtual objects within the physical world. Persistent spatial information enables users to have a shared virtual, as well as physical, experience when interacting with the cross reality system. Further, persistent spatial information may be used in maps of the physical world, enabling one or multiple devices to access and localize into previously stored maps, reducing the need to map a physical space before using the cross reality system in it. Persistent spatial information may be stored as persistent coordinate frames, which may include a transformation relative to a reference orientation and information derived from images in a location corresponding to the persistent coordinate frame.

Abstract: Systems and methods for using stratigraphic heat maps to steer a well being drilled. Data from one or more offset wells can be provided to a computer system and used with data from a well being drilled to generate one or more stratigraphic heat maps during the drilling of the subject well. The stratigraphic heat maps can be displayed and used to determine the location of the wellbore relative to one or more geological formations, including one or more target formations or within a target formation. Based on the use of the heat maps and the location of the wellbore relative to a target, the drill plan can be adjusted or updated and/or one or more drilling parameters or operations may be adjusted to drill the wellbore, such as to drill the wellbore to the target or to maximize the length of the wellbore within a target zone.

Abstract: Systems and methods are described herein to enable the automated and/or user-guided creation, collection, and curating of digital content items that represent a user's experiences, personality, interactions, and legacy. A digital trustee may be assigned to control access to the content after the death of the user. A user may create a death file with content items to be handled in a specific (e.g., user specified) manner after the death of the user. For example, the contents of the death file may be released to a family member or deleted by the system entirely.

Abstract: Present embodiments pertain to systems, apparatuses, and methods for analyzing and reporting the movements in mechanical structures, inanimate physical structures, machinery, and machine components, including automatically detecting aliased frequencies of a component on the structure which exhibits frequencies higher than the maximum frequency of the FFT spectrum calculated from the acquired data. To automatically detect the presence of aliased frequencies, a second virtually identical recording is acquired using a slightly different sampling rate and this provides the basis for detecting frequencies which are greater than the Nyquist sampling rate of the video recording and calculating the true frequency value of the aliased peaks in the frequency spectrum.

Abstract: In one example, a portion of a shed includes a blow molded plastic door, a blow molded plastic wall panel, and a double jointed hinge configured to connect the blow molded plastic door and the blow molded plastic wall panel to each other. The double jointed hinge includes a first hinge element that connectible to the blow molded plastic wall panel, a second hinge element that is connectible to the blow molded plastic door, and a first link and a second link, the first link and the second link configured to connect the first hinge element to the second hinge element, and when the shed portion is in an assembled state, and the blow molded plastic door is fully closed, the first link and the second link are received within a recess cooperatively defined by the blow molded plastic wall panel and the blow molded plastic door.

Abstract: A digital thermometer includes a first oscillator to generate a first clock signal, wherein a period of the first clock signal remains constant in view of changes in a temperature of the apparatus and a first counter coupled to the first oscillator, the first counter to count a fixed number of cycles of the first clock signal associated with a measurement period. The digital thermometer further includes a second oscillator to generate a second clock signal, wherein a period of the second clock signal varies with changes in the temperature and a second counter coupled to the second oscillator, the second counter to generate an output representing a count of a number of cycles of the second clock signal that occur during the measurement period. In addition, the digital thermometer includes calibration circuitry coupled to the second counter, the calibration circuitry to calibrate the output of the second counter to generate a value representing the temperature of the apparatus.

Abstract: Disclosed are systems and methods that automatically classify, segment, and parse content data using artificial intelligence and natural language processing technology, and generate graphical user interfaces that allow end users to dynamically filter content data for display. The systems processes volumes of content data to identify interrogative data, content sources that generated the interrogative data, and subject identifiers relating to the content data. The system generates graphical user interfaces that allow end users to effectively filter the data by choosing between layouts that display one or more of the various categories of data, including the interrogative data, content source identifiers, and/or subject identifiers.

Abstract: The present disclosure generally provides compounds that antagonize certain T2R taste receptors, including related uses, methods, and compositions for the reduction of bitter taste and/or the enhancement of sweet taste. In certain aspects, the disclosure provides flavored articles or flavored compositions comprising such compounds, as well as uses of such compounds to reduce the bitter taste and/or enhance the sweet taste of such flavored articles or flavored compositions.

Abstract: A printing apparatus and method. The printing apparatus is for impinging liquids from at least two liquid sources. The apparatus comprises a first jet actuator configured to dispense a first liquid from a first liquid source and a second jet actuator configured to dispense a second liquid from a second liquid source. The apparatus further comprises an adjustment element configured to adjust a trajectory of at least the first liquid dispensed from the first jet actuator such that the first liquid impinges the second liquid dispensed from the second jet actuator.

Abstract: A method for global navigation satellite system (GNSS)-based navigation may include retrieving terrain data for a geographical region and satellite orbit data for a GNSS comprising a plurality of satellites. Then, for of a plurality of time steps in a time period and for each of a plurality of lateral positions in the geographic region, a minimum height at which each satellite is visible from the lateral position at the time step may be determined. Unique combinations of satellites visible from the lateral position at the time step may be identified and error objects indicating GNSS performance quality corresponding to the unique combination of satellites may be generated. Performance quality information may be produced based on the one or more unique combinations of satellites and the respective one or more error objects. At least one aircraft may be operated based on this performance quality information.

Abstract: Embodiments of the present disclosure relate to real-time digitally signing of a virtual object. The real-time digital signing of a virtual object is provided in a multi-user real-time context between signor and signee that enables the signor to perform the real-time digital signing and the signee to visually experience the real-time signing. The real-time digital signing may be provided to the signor and signee in parallel, and/or one or more additional viewers taking part in the digital signing. Upon completion of the digital signing, some embodiments in near-real-time generate a digital asset that is linked to the virtual object modified with the digital signature, which may be assigned to and/or otherwise linked with the signee for subsequent retrieval and/or use.

Abstract: A method of provisioning a network may include, with a network controller, identifying a first network intent of a computing network based at least in part on an execution of a user interface (UI) or API layer at a client device, and identifying a modification of at least one object within the first network intent within the UI or API layer at the client device as the first network intent is being modified. The modification defines a delta between the first network intent and a second network intent. The method may further include, with a provisioning service executed by the network controller, receiving the delta as a payload from the client device, and provisioning at least one computing device within the computing network based at least in part on the delta. The method further includes automatically modifying the at least one object based on the received delta, including a further modification of the second network intent.

Abstract: A method is provided for dynamic rate limiting of user requests for a service implemented in a computer system. The method includes defining a standard rate limit as an active rate limit for a first user, receiving one or more requests from the first user defining a rate exceeding the active rate limit, and determining a maximum safe system rate for a system implementing the method. The method may then redefine the active rate limit as the lower of the maximum safe system rate and a previously defined burst rate limit associated with the first user. The system may then execute the one or more requests from the first user at or below the redefined active rate limit.

Abstract: An apparatus and method for medical imaging uses a first and second contrast agent, the second agent targeted to a particular tissue type. First images are obtained using the first agent, and second images using the second agent using medical imaging systems. An image processing system is adapted to process the first and second medical images by fitting parameters of a pharmacokinetic model to the first medical images, identifying a nontargeted tissue type, scaling the fitted parameters to best match the nontargeted tissue in the second medical images, executing the pharmacokinetic model to prepare a correction image, and generating corrected medical images by subtracting the correction image from the second medical images.

Abstract: A gas delivery apparatus configured for use with a mechanical ventilator having an atmospheric inlet for drawing in atmospheric gas includes a connecting device configured to connect to an oxygen supply and an air supply and to deliver mixed air and oxygen gas to the atmospheric inlet of the mechanical ventilator. The connecting device further includes a user control for adjusting a fraction of oxygen in the mixed air and oxygen gas. The connecting device comprises a reservoir configured to hold a volume of the mixed air and oxygen gas.

Abstract: A system for maintaining a meta-database including meta-data representing decentralized data from source databases, which cause inefficient selection of modeling data and/or variables. Each of source and meta-data interfaces communicate with the respective database(s). A key variable repository module operably couples the databases and includes an AI program with a scanner algorithm and a profiler algorithm. The scanner algorithm receives the source data from the source interface, compresses the data, and synchronizes the data with the meta-data using the meta-database interface. The profiler algorithm receives the meta-data from the meta-database interface, generates granular data types for the meta-data, determines variables indicative of the meta-data, generates variable probability distributions, produces variable associations, and modifies the meta-database to include the probability distributions and associations using the meta-data interface.