Abstract: Described herein are methods which identify candidate agents as binding to a protein or as a modulator of the binding characteristics or biological activity of a protein. Generally, the methods involve the use of ADP or phosphate. The assays can be used in a high throughput system to obviate the cumbersome steps of using gels or radioactive materials.

Abstract: A system and apparatus including a wireless network architecture that provides broadband data network coverage over an expandable geographic area. A media access control layer is also provided that facilitates access to the broadband wireless network. A high-frequency wireless modem enables high data rate access to the wireless network in a spectrally-efficient manner using SSB modulation. A wideband millimeter-wave antenna includes a cosecant-squared reflector enabling signal propagation between network elements thereby enabling seamless wireless communications. A millimeter-wave polarizer, and a septum polarizer each convert between linear and circular polarization. A cross-shaped horn antenna adapted for circularly polarized signals can also be used in combination with the septum polarizer. A combined horn antenna is fed using a microstrip patch antenna.

Abstract: Described herein are methods which identify candidate agents as binding to a protein or as a modulator of the binding characteristics or biological activity of a protein. Generally, the methods involve the use of ADP or phosphate. The assays can be used in a high throughput system to obviate the cumbersome steps of using gels or radioactive materials.

Abstract: Detection cartridges and associated components, as well as methods of using the same that provide sample materials to a sensor for detection are disclosed. Among the components that may be used in connection with the detection cartridges of the present invention are, e.g., input modules, fluid flow front control features, and volumetric flow rate control features. The modules may include one or more chambers containing different constituents for mixing and/or delivery into a detection cartridge.

Abstract: A technique is provided for classifying images in a library (1) for subsequent selective retrieval. Each library image is segmented (2) into a plurality of coherent regions. Each of the regions is analysed in respect of a plurality of visual properties, each of which is ascribed a number according to the value of the visual property. The property numbers are then compared (4) with bands of the available property range and a computer-readable character, such as a letter of the alphabet, is ascribed to each of the property values. The characters are then arranged (5) in a predetermined order to form a region character string. The strings for each region are then indexed (7) to form an index (8) of the images by region character string. For image retrieval, a target image (10) is analysed in the same way to form region character strings which are then supplied to a text retrieval system (12) for detecting matches with entries in the index (8).

Abstract: A method for monitoring the processing of a workpiece includes directing an incident laser beam onto the workpiece and measuring a signal emitted from the workpiece. At least two signals are generated by a detector based upon the emitted signal. A workpiece processing quality is determined based upon the ratio of the two output signals and a magnitude of one of the two outputs.

Abstract: Described herein are methods which identify candidate agents as binding to a protein or as a modulator of the binding characteristics or biological activity of a protein. Generally, the methods involve the use of ADP or phosphate. The assays can be used in a high throughput system to obviate the cumbersome steps of using gels or radioactive materials.

Abstract: Methods and devices for thermal processing of multiple samples at the same time are disclosed. The assemblies include carriers and sample processing devices with process arrays that include conduits useful in distributing sample materials to a group pf process chambers located in fluid communication with the main conduits. The sample processing devices may include one or more of the following features in various combinations: deformable seals, process chambers connected to the main conduit by feeder conduits exiting the main conduit at offset locations, U-shaped loading chambers, and a combination of melt bonded and adhesively bonded areas. The carriers may be used to apply selective compression to the sample processing devices.

Abstract: Methods and devices for thermal processing of multiple samples at the same time are disclosed. The sample processing devices provide process arrays that include conduits useful in distributing sample materials to a group pf process chambers located in fluid communication with the main conduits. The sample processing devices may include one or more of the following features in various combinations: deformable seals, process chambers connected to the main conduit by feeder conduits exiting the main conduit at offset locations, U-shaped loading chambers, and a combination of melt bonded and adhesively bonded areas.

Abstract: Methods and devices for thermal processing of multiple samples at the same time are disclosed. The sample processing devices provide process arrays that include conduits useful in distributing sample materials to a group pf process chambers located in fluid communication with the main conduits. The sample processing devices may include one or more of the following features in various combinations: deformable seals, process chambers connected to the main conduit by feeder conduits exiting the main conduit at offset locations, U-shaped loading chambers, and a combination of melt bonded and adhesively bonded areas.

Abstract: Methods and devices for thermal processing of multiple samples at the same time are disclosed. The sample processing devices provide process arrays that include conduits useful in distributing sample materials to a group pf process chambers located in fluid communication with the main conduits. The sample processing devices may include one or more of the following features in various combinations: deformable seals, process chambers connected to the main conduit by feeder conduits exiting the main conduit at offset locations, U-shaped loading chambers, and a combination of melt bonded and adhesively bonded areas.

Abstract: An apparatus for document processing comprises an optical sensor including a light source, a light detector and an optical element. The optical sensor is adapted so that, during operation of the apparatus, at least a first portion of light from the source that enters the optical element travels along paths in the optical element so as to be re-directed by total internal reflection toward the detector and wherein the total internal reflection is maintained when the optical element is wet. Signals form the optical sensor may be used to determine, for example, the state of a document storage cassette or the location of a document with respect to the cassette.

Abstract: Apparatus, systems, and methods for monitoring the processing of a workpiece that includes directing an incident laser beam onto the workpiece and using an optical detector for measuring a signal emitted from the workpiece as a result of the incident laser beam. The detector generates at least two signals based upon the optical signal. The method also involves use of a light source monitor in determining workpiece processing quality based upon the quotient of the two outputs as well as a magnitude of one of the two quotients.

Abstract: An all-terrain recreational vehicle comprises a frame, a seat assembly, a plurality of tire assemblies, a steering assembly, a power delivery assembly, a water reservoir, a nozzle and an actuation mechanism. The frame includes a padded roll cage and the seat assembly is attached to the frame. The plurality of tire assemblies is attached to the frame. The steering assembly is connected between the frame and at least two of the tire assemblies. The power delivery assembly is connected to at least one of the tire assemblies. The water reservoir is attached to the frame and the nozzle is in fluid communication with the water reservoir. The actuation mechanism is attached to the frame at a remote location from the nozzle. The actuation mechanism is operably connected between the nozzle and the water reservoir for enabling selective dispensing of water from the water reservoir through the nozzle.

Abstract: The present application is directed to a substrate comprising a first major surface comprising light transmitting areas and light shielding areas. An image reception layer exists on the light shielding areas of the first major surface of the substrate. The substrate is substantially continuous. In some embodiments, the image reception layer is on the second major surface of the substrate. In some embodiments, the light transmitting areas are substantially free of the image reception layer. In certain embodiments, a light shielding coating exists on the light shielding areas between the image reception layer and the substrate.

Abstract: The present application is directed to a substrate comprising a first major surface comprising light transmitting areas and light shielding areas. A reflective image exists on the light shielding areas of the first major surface of the substrate. A transmitted image exists on the first major surface through the light transmitting areas of the first major surface of the substrate. The substrate is substantially continuous and not specularly transmissive.

Abstract: The present application is directed to substrates comprsing light shielding areas and light transmitting areas. In one embodiment, the present application is directed to a substrate comprising a film comprising a light shielding additive. The film comprises a structured surface resulting in thick light shielding areas and relatively thin light transmitting areas. In another embodiment, the present application is directed to a substrate comprising a film comprising a first major surface that is structured with a series of microstructure features and he substrate has light shielding layer is on the first major surface in the light shielding areas. In another embodiment, the light transmitting areas are series of holes through the film having at least two lateral dimensions less than 1.4 mm.

Abstract: The present application is directed to a method of creating a dual appearance comprising providing a substrate. The dual appearance is further created by providing an illumination source proximate to the second major surface of the substrate. A reflective image is provided on the first major surface of the substrate opposite the illumination source. A transmitted image is provided on the second major surface of the substrate between the substrate and the illumination source. Generally, the reflective image is visible with the illumination source off and the transmitted image is visible with the illumination source on.

Abstract: The present application is directed methods of manufacturing dual image substrates. In one embodiment, a light transmitting film is coated with a light shielding substance to provide light shielding areas and a major surface of the film is structured. In another embodiment, a light shielding film is structured to provide light transmitting areas. In another embodiment, a film is printed and then structured to provide light transmitting areas. In another embodiment, a light transmitting film is structured, and then coated with a light shielding coating. The coating is then removed from portions of the structured surface to provide light transmitting areas. The film may also be structured by casting on a structured liner.