Patents by Inventor Kennosuke Matsuda

Kennosuke Matsuda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL FORM OF PYRIMIDINE COMPOUND HAVING DIBENZYLAMINE STRUCTURE
    Publication number: 20170313664
    Abstract: It is an object of the present invention to provide a novel form of (S)-trans-{4-[({2-[({1-[3,5-bis(trifluoromethyl)phenyl]ethyl}{5-[2-(methylsulfonyl)ethoxy]pyrimidin-2-yl}amino)methyl]-4-(trifluoromethyl)phenyl}(ethyl)amino)methyl]cyclohexyl}acetic acid, which is useful for preventing and/or treating diseases such as dyslipidemia. (S)-trans-{4-[({2-[({1-[3,5-bis(Trifluoromethyl)phenyl]ethyl}{5-[2-(methylsulfonyl)ethoxy]pyrimidin-2-yl}amino)methyl]-4-(trifluoromethyl)phenyl}(ethyl)amino)methyl]cyclohexyl}acetic acid hydrochloride.
    Type: Application
    Filed: May 15, 2017
    Publication date: November 2, 2017
    Applicant: KOWA COMPANY, LTD.
    Inventors: Koichi YAMAZAKI, Kennosuke MATSUDA, Taichi KUSAKABE, Tadaaki OHGIYA, Kimiyuki SHIBUYA
  • Form of pyrimidine compound having dibenzylamine structure
    Patent number: 9682942
    Abstract: It is an object of the present invention to provide a novel form of (S)-trans-{4-[({2-[({1-[3,5-bis(trifluoromethyl)phenyl]ethyl}{5-[2-(methylsulfonyl)ethoxy]pyrimidin-2-yl}amino)methyl]-4-(trifluoromethyl)phenyl}(ethyl)amino)methyl]cyclohexyl}acetic acid, which is useful for preventing and/or treating diseases such as dyslipidemia. (S)-trans-{4-[({2-[({1-[3,5-bis(Trifluoromethyl)phenyl]ethyl}{5-[2-(methylsulfonyl)ethoxy]pyrimidin-2-yl}amino)methyl]-4-(trifluoromethyl)phenyl}(ethyl)amino)methyl]cyclohexyl}acetic acid hydrochloride.
    Type: Grant
    Filed: May 30, 2014
    Date of Patent: June 20, 2017
    Assignee: KOWA COMPANY, LTD.
    Inventors: Koichi Yamazaki, Kennosuke Matsuda, Taichi Kusakabe, Tadaaki Ohgiya, Kimiyuki Shibuya
  • Method for preparing optically active 1-bromo-1[3,5-bis(trifluoromethyl)phenyl]ethane
    Patent number: 9272966
    Abstract: A method for preparing optically active 1-bromo-1-[3,5-bis(trifluoromethyl)-phenyl]ethane having a high optical purity, which comprises the step of brominating optically active 1-[3,5-bis(trifluoromethyl)phenyl]ethanol by using, as a brominating agent, (a) a combination of a phosphorus halide and hydrogen bromide, (b) a combination of 1,2-dibromo-1,1,2,2-tetrachloroethane and an organic phosphorous compound represented by the general formula (I): P(R1)(R2)(R3) (in the formula, R1, R2, and R3 independently represent a C6-10 aryl group, a C6-10 aryloxy group, a C1-10 alkyl group, a C1-10 alkoxyl group, a C3-6 cycloalkyl group, or a C3-6 cycloalkoxy group), or (c) a combination of N-bromosuccinimide and a dialkyl sulfide.
    Type: Grant
    Filed: July 21, 2011
    Date of Patent: March 1, 2016
    Assignee: Kowa Company, Ltd.
    Inventors: Taichi Kusakabe, Kennosuke Matsuda, Koichi Yamazaki, Tadaaki Ohgiya, Kimiyuki Shibuya
  • NOVEL FORM OF PYRIMIDINE COMPOUND HAVING DIBENZYLAMINE STRUCTURE
    Publication number: 20160031827
    Abstract: It is an object of the present invention to provide a novel form of (S)-trans-{4-[({2-[({1-[3,5-bis(trifluoromethyl)phenyl]ethyl}{5-[2-(methylsulfonyl)ethoxy]pyrimidin-2-yl}amino)methyl]-4-(trifluoromethyl)phenyl}(ethyl)amino)methyl]cyclohexyl}acetic acid, which is useful for preventing and/or treating diseases such as dyslipidemia. (S)-trans-{4-[({2-[({1-[3,5-bis(Trifluoromethyl)phenyl]ethyl}{5-[2-(methylsulfonyl)ethoxy]pyrimidin-2-yl}amino)methyl]-4-(trifluoromethyl)phenyl}(ethyl)amino)methyl]cyclohexyl}acetic acid hydrochloride.
    Type: Application
    Filed: May 30, 2014
    Publication date: February 4, 2016
    Applicant: KOWA COMPANY, LTD.
    Inventors: Koichi YAMAZAKI, Kennosuke MATSUDA, Taichi KUSAKABE, Tadaaki OHGIYA, Kimiyuki SHIBUYA
  • METHOD FOR PREPARING OPTICALLY ACTIVE 1-BROMO-1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHANE
    Publication number: 20130190540
    Abstract: A method for preparing optically active 1-bromo-1-[3,5-bis(trifluoromethyl)-phenyl]ethane having a high optical purity, which comprises the step of brominating optically active 1-[3,5-bis(trifluoromethyl)phenyl]ethanol by using, as a brominating agent, (a) a combination of a phosphorus halide and hydrogen bromide, (b) a combination of 1,2-dibromo-1,1,2,2-tetrachloroethane and an organic phosphorous compound represented by the general formula (I): P(R1)(R2)(R3) (in the formula, R1, R2, and R3 independently represent a C6-10 aryl group, a C6-10 aryloxy group, a C1-10 alkyl group, a C1-10 alkoxyl group, a C3-6 cycloalkyl group, or a C3-6 cycloalkoxy group), or (c) a combination of N-bromosuccinimide and a dialkyl sulfide.
    Type: Application
    Filed: July 21, 2011
    Publication date: July 25, 2013
    Applicant: Kowa Company, Ltd.
    Inventors: Taichi Kusakabe, Kennosuke Matsuda, Koichi Yamazaki, Tadaaki Ohgiya, Kimiyuki Shibuya