Abstract: A method of training a supervised machine learning system to detect anomalies within transaction data is described. The method includes obtaining a training set of data samples; assigning a label indicating an absence of an anomaly to unlabelled data samples in the training set; partitioning the data of the data samples in the training set into two feature sets, a first feature set representing observable features and a second feature set representing context features; generating synthetic data samples by combining features from the two feature sets that respectively relate to two different uniquely identifiable entities; assigning a label indicating a presence of an anomaly to the synthetic data samples; augmenting the training set with the synthetic data samples; and training a supervised machine learning system with the augmented training set and the assigned labels.

Abstract: A transaction processing system includes a transaction processing module configured to receive first information associated with a first proposed transaction, retrieve second information associated with at least one prior transaction that is associated with the first proposed transaction, and calculate a time-decayed algorithm using the second information to generate third information. The transaction processing system also includes a weighting module communicably coupled to the transaction processing module, wherein the weighting module is configured to receive the third information from the neural-based processing module, apply a weighting factor to the third information to generate fourth information, and calculate at least one processing algorithm using the first information and the fourth information to generate an output. The output of the weighting module is used by an additional transaction processing module to determine whether the first proposed transaction is fraudulent.

Abstract: In one aspect, the present invention provides methods of determining whether an agent is more like a partial agonist of a target molecule than a full agonist of the same target molecule. In another aspect, the present invention provides methods to select a candidate compound that may reduce blood plasma glucose concentration in a mammal. Populations of genes are provided that are useful in the practice of the present invention.

Abstract: Substituted 2-aminopyridine compounds of Formula (I) and pharmaceutically acceptable salts which have been found useful in the treatment of nitric oxide synthase mediated diseases and disorders.

Abstract: An apparatus and method for rotating an optical element, such as a diffraction grating or mirror, utilizes a moving coil actuator and an optical encoder to provide precise element position control. The moving coil actuator, which is coupled to the optical element, is comprised of a coil immersed in a magnetic field created by a pair of magnets. Current flowing in the coil windings causes the coil, and ultimately the optical element, to rotate. An optical encoder monitors the rotation of the element and provides rotation signals representative of the instantaneous element position to an actuator control circuit. The actuator control circuit phase shifts the rotation signals and compares the phase shifted rotation signals to a desired reference signal to generate position and velocity error signals. In a track follow mode, the position error signal is applied to the moving coil actuator via a loop compensator.

Abstract: Disclosed is an improved viscous oil recovery method employing the injection of a thermal recovery fluid which may be steam or a mixture of steam and additives, and cycles of pressurization and drawdown. First the thermal recovery fluid is injected and production is restricted in order to increase the pressure in the reservoir. Injection is then terminated or decreased and production is increased in order to effect a pressure drawdown in the reservoir. Thereafter the production rate is decreased or production wells are shut in completely and non-condensable gas is injected to raise the pressure in the reservoir to a value which is from 50 to 90 percent of the final target pressure, after which the thermal recovery fluid is again injected into the formation to rebuild reservoir pressure with restricted production. Finally, production rate is increased and thermal recovery fluid injection is reduced or terminated in order to accomplish another reservoir drawdown cycle.