Patents by Inventor Kensaku Hosoguchi

Kensaku Hosoguchi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTIBODY VARIANT AND ISOFORM WITH LOWERED BIOLOGICAL ACTIVITY
    Publication number: 20200283544
    Abstract: As antibody variants and isoforms having reduced FVIII mimetic activity than Emicizumab, the antibody variants having some specific amino acid residues in the variable region cleaved out and missing (Q-CDR-Clipped Variants) and the antibody isoforms having inter-heavy chain disulfide bonds less susceptible to reduction under mild reducing conditions (Protected Disulfide Isoforms) are provided.
    Type: Application
    Filed: October 31, 2018
    Publication date: September 10, 2020
    Applicant: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Kensaku Hosoguchi, Maki Kuwayama, Chifumi Seida, Yosuke Watanabe, Nobuyuki Tanaka, Satoshi Saitoh, Masakazu Fukuda