Abstract: The invention provides a cosmetic product which has a good texture and allows full expression of the inherent functions of ceramide as an intercellular lipid, such as skin barrier function and hair protection effect, as well as nanoparticles for cosmetics and powder for cosmetics which may be used in the above cosmetic product, exhibit good skin barrier function and hair protection effect, and are easy to incorporate into the above cosmetic product. The cosmetic product, the nanoparticles, and the powder for cosmetics according to the present invention contain a polymer obtained by polymerization of a monomer material containing a glycerol(meth)acrylate monomer represented by the formula (1): (R1: —H, —CH3; R2: —(CH2)n-; n is an integer of 1 to 4).

Abstract: The present invention relates to an inhibitor capable of increasing accuracy of the reaction in hybridization, and inhibiting nonspecific hybridization, a clinical diagnostic reagent, and a method of clinical analysis whereby nonspecific hybridization in clinical analysis is inhibited, and a target nucleic substance is detected easily with high accuracy. The inhibitor and the clinical diagnostic reagent contains polymer (H) having a nonspecific hybridization inhibitory action. The polymer has in its molecule at least one of carboxyl and sulfone groups, and phosphorylcholine-like groups, and has a weight average molecular weight of 1000 to 5000000. The method of clinical analysis includes contacting a sample with a test agent capable of hybridizing with a specific nucleic substance in the presence of the inhibitor.

Abstract: An agitation method for mixing a solution and a solvent to precipitate a solid substance from the solution. The method includes preparing an agitation mixer including an agitation vessel, an impeller rotated in the agitation vessel, and a feed pipe connected to the agitation vessel and having a multiple pipe structure including an outer pipe and an inner pipe arranged in the outer pipe. A shearing clearance is formed in the agitation vessel between the impeller and the feed pipe. The method further includes shearing the solution and the solvent by rotating the impeller to precipitate the solid substance while feeding the solution and the solvent into the shearing clearance from the outer pipe and the inner pipe.

Abstract: The invention provides a quick-drying disinfectant gel for hands that spreads well in rubbing into hands, spreads easily over the hands, forms no scum, and is not sticky before and after drying. The disinfectant gel for hands of the invention contains 0.01 to 2.0 wt % of a maleic anhydride polymer, 0.01 to 5.0 wt % of polysaccharides, 40 to 95 wt % of a lower alcohol, and water, with the total being 100 wt %.

Abstract: The invention provides a cosmetic product which has a good texture and allows full expression of the inherent functions of ceramide as an intercellular lipid, such as skin barrier function and hair protection effect, as well as nanoparticles for cosmetics and powder for cosmetics which may be used in the above cosmetic product, exhibit good skin barrier function and hair protection effect, and are easy to incorporate into the above cosmetic product. The cosmetic product, the nanoparticles, and the powder for cosmetics according to the present invention contain a polymer obtained by polymerization of a monomer material containing a glycerol (meth)acrylate monomer represented by the formula (1): (R1: —H, —CH3; R2: —(CH2)n-; n is an integer of 1 to 4).

Abstract: An agitation method for mixing a solution and a solvent to precipitate a solid substance from the solution. The method includes preparing an agitation mixer including an agitation vessel, an impeller rotated in the agitation vessel, and a feed pipe connected to the agitation vessel and having a multiple pipe structure including an outer pipe and an inner pipe arranged in the outer pipe. A shearing clearance is formed in the agitation vessel between the impeller and the feed pipe. The method further includes shearing the solution and the solvent by rotating the impeller to precipitate the solid substance while feeding the solution and the solvent into the shearing clearance from the outer pipe and the inner pipe.

Abstract: The invention provides a cosmetic product which has a good texture and allows full expression of the inherent functions of ceramide as an intercellular lipid, such as skin barrier function and hair protection effect, as well as nanoparticles for cosmetics and powder for cosmetics which may be used in the above cosmetic product, exhibit good skin barrier function and hair protection effect, and are easy to incorporate into the above cosmetic product. The cosmetic product, the nanoparticles, and the powder for cosmetics according to the present invention contain a polymer obtained by polymerization of a monomer material containing a glycerol(meth)acrylate monomer represented by the formula (1): (R1: —H, —CH3; R2: —(CH2)n-; n is an integer of 1 to 4).

Abstract: The invention provides a quick-drying disinfectant gel for hands that spreads well in rubbing into hands, spreads easily over the hands, forms no scum, and is not sticky before and after drying. The disinfectant gel for hands of the invention contains 0.01 to 2.0 wt % of a maleic anhydride polymer, 0.01 to 5.0 wt % of polysaccharides, 40 to 95 wt % of a lower alcohol, and water, with the total being 100 wt %.

Abstract: The present invention provides an agglutination immunoassay, wherein the agglutination of insoluble carrier particles such as latex are stabilized and uniformized to give good reproducibility, and a reagent therefor. In the agglutination immunoassay which comprises allowing an antigenic substance in a sample to bind to insoluble carrier particles carrying substantially neither antigens nor antibodies thereon, and allowing an antibody or an antibody complex which reacts specifically to the antigenic substance to bind to the antigenic substance to give a selective agglutination of the insoluble carrier particles, a homopolymer prepared by polymerization of a monomer such as 2-methacryloyloxyethyl phosphorylcholine having a phosphorylcholine group and a vinyl group, or a copolymer prepared by polymerization of a monomer having a phosphorylcholine group and a vinyl group, with a monomer having a vinyl group such as n-butyl methacrylate is used.

Abstract: A composition for hydrogels which comprises (A1) a copolymer which comprises 25 to 97 mol % of unit (a) derived from a compound represented by formula (1) and 3 to 75 mol % of unit (b) derived from a monomer represented by formula (2) and is soluble in aqueous media and (B) a polymer which has hydrophilic groups such as hydroxyl or carboxyl groups and is soluble in aqueous media; and a hydrogel comprising the composition. (X represents a divalent organic residue; Y represents alkyleneoxy, etc.; Z, R1, R2, R3, R4, and L2 each represents hydrogen, etc.; and L1 represents —C6H4—, etc.

Abstract: A medical material having a surface which is safe and excellent in stability with the lapse of time and has a high durability as needed in establishing a long-lasting surface lubricity in a wet state and an excellent compatibility with blood, and a method for producing the same. These materials are obtained by forming a coating layer with a coating material containing a polymeric substance (A) having a heterocyclic group represented by the formula (1) on at least a part of a surface of a medical material base, and then ring-opening the heterocyclic group remaining in the coating layer by a nucleophilic compound (N): wherein X represents O, NH or S; and R1 represents H or CH3.

Abstract: The present invention relates to an inhibitor capable of increasing accuracy of the reaction in hybridization, and inhibiting nonspecific hybridization, a clinical diagnostic reagent, and a method of clinical analysis whereby nonspecific hybridization in clinical analysis is inhibited, and a target nucleic substance is detected easily with high accuracy. The inhibitor and the clinical diagnostic reagent contains polymer (H) having a nonspecific hybridization inhibitory action. The polymer has in its molecule at least one of carboxyl and sulfone groups, and phosphorylcholine-like groups, and has a weight average molecular weight of 1000 to 5000000. The method of clinical analysis includes contacting a sample with a test agent capable of hybridizing with a specific nucleic substance in the presence of the inhibitor.

Abstract: A wound-covering agent containing a polymer having a group represented by formula (I) (wherein R1, R2 and R3 are the same or different and each represents hydrogen atom or C1-4 alkyl, and m is an integer of 2 to 4); a wound-covering material containing the preparation; and a method of wound healing which comprises the step of covering the wound of a subject with the wound-covering material to protect the wound.

Abstract: The present invention provides an agglutination immunoassay, wherein the agglutination of insoluble carrier particles such as latex are stabilized and uniformized to give good reproducibility, and a reagent therefor. In the agglutination immunoassay which comprises allowing an antigenic substance in a sample to bind to insoluble carrier particles carrying substantially neither antigens nor antibodies thereon, and allowing an antibody or an antibody complex which reacts specifically to the antigenic substance to bind to the antigenic substance to give a selective agglutination of the insoluble carrier particles, a homopolymer prepared by polymerization of a monomer such as 2-methacryloyloxyethyl phosphorylcholine having a phosphorylcholine group and a vinyl group, or a copolymer prepared by polymerization of a monomer having a phosphorylcholine group and a vinyl group, with a monomer having a vinyl group such as n-butyl methacrylate is used.

Abstract: An object of the present invention is to provide a method and a reagent for measuring the subject substances containing high concentration of C-reactive protein without dilution while avoiding prozone phenomenon.

Abstract: A method for producing an aqueous solution of a polymer having a phosphorylcholine group in which a polymerizable composition containing a polymerizable monomer having the phosphorylcholine group represented by the formula (1) is polymerized in the presence of a non-metal polymerization initiator soluble in a water-containing medium, to obtain a crude polymer aqueous solution, and the crude polymer aqueous solution is purified with a separation membrane, and an aqueous solution of the polymer having the phosphorylcholine group obtained by the method and having not more than 2000 ppm of impurities.

Abstract: A polymerized product of protein, comprising a polymer of one or more protein-containing monomers represented by the general formulaP.sub.r --?(Y).sub.k --(X).sub.m --R.sup.1 !.sub.n (1)wherein R.sup.1 represents a polymerizable group capable of causing a radical polymerization, P.sub.r denotes a protein residue, Y denotes a group formed from a functional group in said protein and the functional group R.sub.2 of the modifying agent given below, X denotes an organic divalent radical, k is zero or 1, m is zero or 1 and n is a numeral of 1 or higher,said protein-containing monomer being obtained by reacting a protein with a modifying agent represented by the general formula,R.sup.2 --(X).sub.m --R.sup.1 (2)wherein R.sub.2 represents a functional group capable of combining with a functional group of protein and R.sup.1, X and m are as given above.