Patents by Inventor Kenshiro Shuto
Kenshiro Shuto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20120276179Abstract: The invention provides a cosmetic product which has a good texture and allows full expression of the inherent functions of ceramide as an intercellular lipid, such as skin barrier function and hair protection effect, as well as nanoparticles for cosmetics and powder for cosmetics which may be used in the above cosmetic product, exhibit good skin barrier function and hair protection effect, and are easy to incorporate into the above cosmetic product. The cosmetic product, the nanoparticles, and the powder for cosmetics according to the present invention contain a polymer obtained by polymerization of a monomer material containing a glycerol(meth)acrylate monomer represented by the formula (1): (R1: —H, —CH3; R2: —(CH2)n-; n is an integer of 1 to 4).Type: ApplicationFiled: June 29, 2012Publication date: November 1, 2012Applicant: NOF CORPORATIONInventors: Hiroki Fukui, Yoshimi Sekine, Daisuke Kayaba, Eui-chul Kang, Atsuhiko Ogura, Kenshiro Shuto
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Patent number: 8252531Abstract: The present invention relates to an inhibitor capable of increasing accuracy of the reaction in hybridization, and inhibiting nonspecific hybridization, a clinical diagnostic reagent, and a method of clinical analysis whereby nonspecific hybridization in clinical analysis is inhibited, and a target nucleic substance is detected easily with high accuracy. The inhibitor and the clinical diagnostic reagent contains polymer (H) having a nonspecific hybridization inhibitory action. The polymer has in its molecule at least one of carboxyl and sulfone groups, and phosphorylcholine-like groups, and has a weight average molecular weight of 1000 to 5000000. The method of clinical analysis includes contacting a sample with a test agent capable of hybridizing with a specific nucleic substance in the presence of the inhibitor.Type: GrantFiled: April 25, 2002Date of Patent: August 28, 2012Assignee: NOF CorporationInventors: Shujiro Sakaki, Kenshiro Shuto, Mamoru Tsuchida, Yoshihiro Ashihara, Mitsuo Isomura
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Patent number: 7993052Abstract: An agitation method for mixing a solution and a solvent to precipitate a solid substance from the solution. The method includes preparing an agitation mixer including an agitation vessel, an impeller rotated in the agitation vessel, and a feed pipe connected to the agitation vessel and having a multiple pipe structure including an outer pipe and an inner pipe arranged in the outer pipe. A shearing clearance is formed in the agitation vessel between the impeller and the feed pipe. The method further includes shearing the solution and the solvent by rotating the impeller to precipitate the solid substance while feeding the solution and the solvent into the shearing clearance from the outer pipe and the inner pipe.Type: GrantFiled: September 28, 2007Date of Patent: August 9, 2011Assignee: NOF CorporationInventors: Nobuyuki Sakamoto, Kenshiro Shuto, Satoshi Yamada, Hirofumi Irie
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Patent number: 7824665Abstract: The invention provides a quick-drying disinfectant gel for hands that spreads well in rubbing into hands, spreads easily over the hands, forms no scum, and is not sticky before and after drying. The disinfectant gel for hands of the invention contains 0.01 to 2.0 wt % of a maleic anhydride polymer, 0.01 to 5.0 wt % of polysaccharides, 40 to 95 wt % of a lower alcohol, and water, with the total being 100 wt %.Type: GrantFiled: September 20, 2006Date of Patent: November 2, 2010Assignee: NOF CorporationInventors: Koji Miyamoto, Yoshimi Sekine, Hiroki Fukui, Kenshiro Shuto
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Publication number: 20100040697Abstract: The invention provides a cosmetic product which has a good texture and allows full expression of the inherent functions of ceramide as an intercellular lipid, such as skin barrier function and hair protection effect, as well as nanoparticles for cosmetics and powder for cosmetics which may be used in the above cosmetic product, exhibit good skin barrier function and hair protection effect, and are easy to incorporate into the above cosmetic product. The cosmetic product, the nanoparticles, and the powder for cosmetics according to the present invention contain a polymer obtained by polymerization of a monomer material containing a glycerol (meth)acrylate monomer represented by the formula (1): (R1: —H, —CH3; R2: —(CH2)n-; n is an integer of 1 to 4).Type: ApplicationFiled: October 19, 2009Publication date: February 18, 2010Applicant: NOF CORPORATIONInventors: Hiroki Fukui, Yoshimi Sekine, Daisuke Kayaba, Eui-chul Kang, Atsuhiko Ogura, Kenshiro Shuto
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Publication number: 20080080304Abstract: An agitation method for mixing a solution and a solvent to precipitate a solid substance from the solution. The method includes preparing an agitation mixer including an agitation vessel, an impeller rotated in the agitation vessel, and a feed pipe connected to the agitation vessel and having a multiple pipe structure including an outer pipe and an inner pipe arranged in the outer pipe. A shearing clearance is formed in the agitation vessel between the impeller and the feed pipe. The method further includes shearing the solution and the solvent by rotating the impeller to precipitate the solid substance while feeding the solution and the solvent into the shearing clearance from the outer pipe and the inner pipe.Type: ApplicationFiled: September 28, 2007Publication date: April 3, 2008Applicant: NOF CORPORATIONInventors: Nobuyuki SAKAMOTO, Kenshiro SHUTO, Satoshi YAMADA, Hirofumi IRIE
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Publication number: 20070148121Abstract: The invention provides a cosmetic product which has a good texture and allows full expression of the inherent functions of ceramide as an intercellular lipid, such as skin barrier function and hair protection effect, as well as nanoparticles for cosmetics and powder for cosmetics which may be used in the above cosmetic product, exhibit good skin barrier function and hair protection effect, and are easy to incorporate into the above cosmetic product. The cosmetic product, the nanoparticles, and the powder for cosmetics according to the present invention contain a polymer obtained by polymerization of a monomer material containing a glycerol(meth)acrylate monomer represented by the formula (1): (R1: —H, —CH3; R2: —(CH2)n-; n is an integer of 1 to 4).Type: ApplicationFiled: October 25, 2006Publication date: June 28, 2007Inventors: Hiroki Fukui, Yoshimi Sekine, Daisuke Kayaba, Eui-chul Kang, Atsuhiko Ogura, Kenshiro Shuto
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Publication number: 20070065388Abstract: The invention provides a quick-drying disinfectant gel for hands that spreads well in rubbing into hands, spreads easily over the hands, forms no scum, and is not sticky before and after drying. The disinfectant gel for hands of the invention contains 0.01 to 2.0 wt % of a maleic anhydride polymer, 0.01 to 5.0 wt % of polysaccharides, 40 to 95 wt % of a lower alcohol, and water, with the total being 100 wt %.Type: ApplicationFiled: September 20, 2006Publication date: March 22, 2007Inventors: Koji Miyamoto, Yoshimi Sekine, Hiroki Fukui, Kenshiro Shuto
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Patent number: 7166476Abstract: The present invention provides an agglutination immunoassay, wherein the agglutination of insoluble carrier particles such as latex are stabilized and uniformized to give good reproducibility, and a reagent therefor. In the agglutination immunoassay which comprises allowing an antigenic substance in a sample to bind to insoluble carrier particles carrying substantially neither antigens nor antibodies thereon, and allowing an antibody or an antibody complex which reacts specifically to the antigenic substance to bind to the antigenic substance to give a selective agglutination of the insoluble carrier particles, a homopolymer prepared by polymerization of a monomer such as 2-methacryloyloxyethyl phosphorylcholine having a phosphorylcholine group and a vinyl group, or a copolymer prepared by polymerization of a monomer having a phosphorylcholine group and a vinyl group, with a monomer having a vinyl group such as n-butyl methacrylate is used.Type: GrantFiled: August 28, 2001Date of Patent: January 23, 2007Assignees: Kyowa Medex Co., Ltd., NOF CorporationInventors: Kayoko Shigenobu, Kenshiro Shuto, Shujiro Sakaki
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Patent number: 6858673Abstract: A composition for hydrogels which comprises (A1) a copolymer which comprises 25 to 97 mol % of unit (a) derived from a compound represented by formula (1) and 3 to 75 mol % of unit (b) derived from a monomer represented by formula (2) and is soluble in aqueous media and (B) a polymer which has hydrophilic groups such as hydroxyl or carboxyl groups and is soluble in aqueous media; and a hydrogel comprising the composition. (X represents a divalent organic residue; Y represents alkyleneoxy, etc.; Z, R1, R2, R3, R4, and L2 each represents hydrogen, etc.; and L1 represents —C6H4—, etc.Type: GrantFiled: May 9, 2000Date of Patent: February 22, 2005Assignee: NOF CorporationInventors: Nobuyuki Sakamoto, Kenshiro Shuto, Shujiro Sakaki, Ken Suzuki, Shinji Tanaka
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Patent number: 6828028Abstract: A medical material having a surface which is safe and excellent in stability with the lapse of time and has a high durability as needed in establishing a long-lasting surface lubricity in a wet state and an excellent compatibility with blood, and a method for producing the same. These materials are obtained by forming a coating layer with a coating material containing a polymeric substance (A) having a heterocyclic group represented by the formula (1) on at least a part of a surface of a medical material base, and then ring-opening the heterocyclic group remaining in the coating layer by a nucleophilic compound (N): wherein X represents O, NH or S; and R1 represents H or CH3.Type: GrantFiled: January 25, 2002Date of Patent: December 7, 2004Assignee: NOF CorporationInventors: Hiroki Fukui, Ken Suzuki, Kenshiro Shuto, Nobuyuki Yamamoto, Kazuhiko Ishihara, Nobuo Nakabayashi
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Publication number: 20040219546Abstract: The present invention relates to an inhibitor capable of increasing accuracy of the reaction in hybridization, and inhibiting nonspecific hybridization, a clinical diagnostic reagent, and a method of clinical analysis whereby nonspecific hybridization in clinical analysis is inhibited, and a target nucleic substance is detected easily with high accuracy. The inhibitor and the clinical diagnostic reagent contains polymer (H) having a nonspecific hybridization inhibitory action. The polymer has in its molecule at least one of carboxyl and sulfone groups, and phosphorylcholine-like groups, and has a weight average molecular weight of 1000 to 5000000. The method of clinical analysis includes contacting a sample with a test agent capable of hybridizing with a specific nucleic substance in the presence of the inhibitor.Type: ApplicationFiled: February 11, 2004Publication date: November 4, 2004Inventors: Shujiro Sakaki, Kenshiro Shuto, Mamoru Tsuchida, Yoshihiro Ashihara, Mitsuo Isomura
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Patent number: 6706260Abstract: A wound-covering agent containing a polymer having a group represented by formula (I) (wherein R1, R2 and R3 are the same or different and each represents hydrogen atom or C1-4 alkyl, and m is an integer of 2 to 4); a wound-covering material containing the preparation; and a method of wound healing which comprises the step of covering the wound of a subject with the wound-covering material to protect the wound.Type: GrantFiled: January 5, 2001Date of Patent: March 16, 2004Assignees: NOF CorporationInventors: Shinji Tanaka, Ken Suzuki, Kenshiro Shuto, Akio Hayashi, Nobuo Nakabayashi, Kazuhiko Ishihara
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Publication number: 20030166302Abstract: The present invention provides an agglutination immunoassay, wherein the agglutination of insoluble carrier particles such as latex are stabilized and uniformized to give good reproducibility, and a reagent therefor. In the agglutination immunoassay which comprises allowing an antigenic substance in a sample to bind to insoluble carrier particles carrying substantially neither antigens nor antibodies thereon, and allowing an antibody or an antibody complex which reacts specifically to the antigenic substance to bind to the antigenic substance to give a selective agglutination of the insoluble carrier particles, a homopolymer prepared by polymerization of a monomer such as 2-methacryloyloxyethyl phosphorylcholine having a phosphorylcholine group and a vinyl group, or a copolymer prepared by polymerization of a monomer having a phosphorylcholine group and a vinyl group, with a monomer having a vinyl group such as n-butyl methacrylate is used.Type: ApplicationFiled: February 28, 2003Publication date: September 4, 2003Inventors: Kayoko Shigenobu, Kenshiro Shuto, Shujiro Sakaki
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Publication number: 20010026927Abstract: An object of the present invention is to provide a method and a reagent for measuring the subject substances containing high concentration of C-reactive protein without dilution while avoiding prozone phenomenon.Type: ApplicationFiled: February 28, 2001Publication date: October 4, 2001Inventors: Hiroaki Yokohama, Harumi Umehara, Shigeru Matsumori, Satoshi Yamada, Kenshiro Shuto, Shujiro Sakaki, Ken Suzuki
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Patent number: 6204324Abstract: A method for producing an aqueous solution of a polymer having a phosphorylcholine group in which a polymerizable composition containing a polymerizable monomer having the phosphorylcholine group represented by the formula (1) is polymerized in the presence of a non-metal polymerization initiator soluble in a water-containing medium, to obtain a crude polymer aqueous solution, and the crude polymer aqueous solution is purified with a separation membrane, and an aqueous solution of the polymer having the phosphorylcholine group obtained by the method and having not more than 2000 ppm of impurities.Type: GrantFiled: December 2, 1996Date of Patent: March 20, 2001Assignees: NOF Corporation, Japan Science and Technology CorporationInventors: Kenshiro Shuto, Kazuo Matsuyama, Nobuo Nakabayashi, Kazuhiko Ishihara
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Patent number: 5807942Abstract: A polymerized product of protein, comprising a polymer of one or more protein-containing monomers represented by the general formulaP.sub.r --?(Y).sub.k --(X).sub.m --R.sup.1 !.sub.n (1)wherein R.sup.1 represents a polymerizable group capable of causing a radical polymerization, P.sub.r denotes a protein residue, Y denotes a group formed from a functional group in said protein and the functional group R.sub.2 of the modifying agent given below, X denotes an organic divalent radical, k is zero or 1, m is zero or 1 and n is a numeral of 1 or higher,said protein-containing monomer being obtained by reacting a protein with a modifying agent represented by the general formula,R.sup.2 --(X).sub.m --R.sup.1 (2)wherein R.sub.2 represents a functional group capable of combining with a functional group of protein and R.sup.1, X and m are as given above.Type: GrantFiled: June 4, 1996Date of Patent: September 15, 1998Assignee: NOF CorporationInventors: Shujiro Sakaki, Satoshi Yamada, Motohiro Mitani, Kenshiro Shuto, Yasumi Koinuma