Abstract: An imaging flow cytometry system and method which includes a flow chamber, light obscuration analysis and imaging optics, image capturing system, device to regulate fluid flow through the chamber, and backlighting generator. The flow cell is configured so that light obscuration signals can be detected from the same passing particles that are imaged.

Abstract: An imaging flow cytometry system and method which includes a flow chamber, light obscuration analysis and imaging optics, image capturing system, device to regulate fluid flow through the chamber, and backlighting generator. The flow cell is configured so that light obscuration signals can be detected from the same passing particles that are imaged.

Abstract: A particle detection system with a detection mechanism that includes detectors positioned to detect two different ranges of fluorescence produced by particles in the fluid in a flow chamber. Each of the detectors is arranged to generating a trigger signal whenever fluorescence is detected. The system and related method enhance the accuracy and sensitivity of blue-green algae monitoring by utilizing imaging flow cytometry combined with particle analysis and the measurement of the ratio of each particle's phycocyanin to chlorophyll b detected by using the two detectors configured for detection of two different fluorescence ranges, one associated with the phycocyanin and the other associated with the chlorophyll b. Captured images are be used in comparison to known images of a library of images using a support vector machine classifier.

Abstract: A flow chamber, imaging objective, condenser and imaging light source as part of an optical system includes an oil-immersion objective and high numerical aperture condenser matched to a rectangular flow chamber. The oil-immersion objective and flow chamber include a high index of refraction immersion oil so as to enhance the optical resolution and optical coupling therethrough. The flow chamber is reinforced with stiffening wires that are arranged to extend above a surface of the sidewalls of the flow chamber so as to function as a barrier to leakage of the immersion oil away from the surface of the flow chamber.

Abstract: A particle detection system with a detection mechanism that includes detectors positioned to detect two different ranges of fluorescence produced by particles in the fluid in a flow chamber. Each of the detectors is arranged to generating a trigger signal whenever fluorescence is detected. The system and related method enhance the accuracy and sensitivity of blue-green algae monitoring by utilizing imaging flow cytometry combined with particle analysis and the measurement of the ratio of each particle's phycocyanin to chlorophyll b detected by using the two detectors configured for detection of two different fluorescence ranges, one associated with the phycocyanin and the other associated with the chlorophyll b. Captured images are be used in comparison to known images of a library of images using a support vector machine classifier.

Abstract: An imaging flow cytometry system including dark field illumination to contrast particles in a flowing fluid. The system includes a condenser with blocking aperture and a numerical aperture of no less than 0.4. The system also includes a microscope objective for focusing dark field illuminated particles, wherein the objective has a numerical aperture of 0.3. The system further includes imaging optics, an image capturing system and a backlighting generator.

Abstract: An imaging flow cytometry system and method which includes a flow chamber, fluorescence analysis and imaging optics, image capturing system, device to regulate fluid flow through the chamber, and backlighting generator. The flow cell is configured so as to enhance the fluorescence signal collection by the system with total internal reflections. The fluorescence collection optics are configured to enhance the collection of the fluorescence from the side of the flow cell and concentrate it on light detectors.

Abstract: A fan coil block of the present invention preferably includes a fan for drawing air and a cooling device for cooling air drawn by the fan. A flexible air handling system of the present invention preferably includes a fan coil block that is supportable overhead by an overhead support system. The present invention is also directed to an air handling method that includes the steps of providing an overhead support system for supporting overhead devices, defining a return air chase within the interior space of a building, and supporting a fan coil block above or within the return air chase using the overhead support system. The fan coil block draws and cools air from the return air chase and returns the cooled air to a plenum above the overhead support system.

Abstract: An imaging flow cytometry system and method which includes a flow chamber, fluorescence analysis and imaging optics, image capturing system, device to regulate fluid flow through the chamber, and backlighting generator. The flow cell is configured so as to enhance the fluorescence signal collection by the system with total internal reflections. The fluorescence collection optics are configured to enhance the collection of the fluorescence from the side of the flow cell and concentrate it on light detectors.

Abstract: An imaging flow cytometry system and method which includes a flow chamber, tracking mirror, microscope and imaging optics, image capturing system, device to regulate fluid flow through the chamber, and backlighting generator. The tracking mirror moves at a rate matched to the particle velocity in the flow chamber so as to enhance the sample flow rates possible with the system while maintaining clear and accurate imaging. The backlighting generator passes through the flow chamber and the objective before being focused on the image capturing system. Detected scatter events initiate tracking by the mirror, resulting in imaging with reduced motion blur even at high rates of flow.

Abstract: A flow chamber, imaging objective, condenser and imaging light source as part of an optical system includes an oil-immersion objective and high numerical aperture condenser matched to a rectangular flow chamber. The oil-immersion objective and flow chamber include a high index of refraction immersion oil so as to enhance the optical resolution and optical coupling therethrough. The imaging light source generates light which passes through the condenser, the flow chamber and then the objective before being focused onto an imaging camera. Fluorescence excitation passes through the objective to the flow chamber where the oil immersion configuration enhances the focus and collection of the light back through the objective.

Abstract: A particle detection system with a detection mechanism that includes detectors positioned to detect two different ranges of fluorescence produced by particles in the fluid in a flow chamber. Each of the detectors is arranged to generating a trigger signal whenever fluorescence is detected. The system and related method enhance the accuracy and sensitivity of blue-green algae monitoring by utilizing imaging flow cytometry combined with particle analysis and the measurement of the ratio of each particle's phycocyanin to chlorophyll b detected by using the two detectors configured for detection of two different fluorescence ranges, one associated with the phycocyanin and the other associated with the chlorophyll b. Optionally, captured images may be used in comparison to known images of a library of images.

Abstract: A flow chamber, imaging objective, condenser and imaging light source as part of an optical system includes an oil-immersion objective and high numerical aperture condenser matched to a rectangular flow chamber. The oil-immersion objective and flow chamber include a high index of refraction immersion oil so as to enhance the optical resolution and optical coupling therethrough. The imaging light source generates light which passes through the condenser, the flow chamber and then the objective before being focused onto an imaging camera. Fluorescence excitation passes through the objective to the flow chamber where the oil immersion configuration enhances the focus and collection of the light back through the objective.

Abstract: A system for converting a snowmobile into a wheeled vehicle is disclosed, and comprises a pair of wheel mounting assemblies for each being mounted on one of the front skid support assemblies of the snowmobile, and a swing arm for mounting on the snowmobile in a manner such that the swing arm is pivotable with respect to the frame. The swing arm has a forward end and a rearward end, and is mountable on the drive shaft such that the swing arm is pivotable with respect to the drive shaft. An axle is mounted on the swing arm toward the rearward end thereof, and a suspension mounting assembly is provided for mounting on the frame of the snowmobile and controlling pivot movement of the swing arm.

Abstract: A reflective Fresnel lens for shaping an incident wave for efficiently delivering the incident wave to an array of receivers, having a wavelength within a predetermined range. The Fresnel lens comprises a ground plate and a plurality of reflective elements formed at various levels of the ground plate. The predetermined range includes millimeter wavelength range, sub-millimeter wavelength range or microwave wavelength range.

Abstract: A ridge waveguide filter having a slow-wave structure. The ridge waveguide has an elongate hollow tube formed of a conductive sidewall. At least a first part of the conductive sidewall periodically is recessed along an elongate direction of the hollow tube, such that a plurality of ridges is formed to project in the hollow tube. The sidewall is fabricated from metallic materials. The hollow tube includes a rectangular hollow tube or a circular hollow tube, for example. The ridges are equally spaced from and parallel with each other. Each of the ridges has a bottom surface parallel with a second part of the conductive sidewall. The second part of the conductive sidewall is opposite to the first part of the conductive sidewall.

Abstract: A ridge waveguide filter having a slow-wave structure. The ridge waveguide has an elongate hollow tube formed of a conductive sidewall. At least a first part of the conductive sidewall periodically is recessed along an elongate direction of the hollow tube, such that a plurality of ridges is formed to project in the hollow tube. The sidewall is fabricated from metallic materials. The hollow tube includes a rectangular hollow tube or a circular hollow tube, for example. The ridges are equally spaced from and parallel with each other. Each of the ridges has a bottom surface parallel with a second part of the conductive sidewall. The second part of the conductive sidewall is opposite to the first part of the conductive sidewall.

Abstract: A distributed interconnect and a method is provided for interconnecting electrical components which minimizes coupling inductance and increases bandwidth. The interconnect includes a transmission line with a first and second conductive transmission element. The first conductive transmission element is disposed between a first and second terminal, and has an impedance characteristic that increases from the first terminal to the second terminal. The second conductive transmission element is disposed between a third and fourth terminal, and has an impedance characteristic that increases from the third terminal to said fourth terminal. The conductive transmission elements are furthermore positioned in parallel alignment with respect to each other.

Abstract: The invention relates to a process for converting Taxol A, B and C to Taxol primary amine which can then be easily and efficiently converted to Taxol A or docetaxel, thereby significantly increasing the yield of these products from biomass. The method includes the removal of the amide from the side-chain with Schwartz's reagent to form an imine, followed by the hydrolysis of the imine to the primary amine. The primary amine can then be converted to Taxol A or docetaxel. New Taxol imine compounds and primary amine salts have been formed by this process.