Patents by Inventor Kent Fagan

Kent Fagan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Modified cyclic nucleotide gated ion channels
    Patent number: 7341836
    Abstract: The present invention provides modified cyclic nucleotide gated (CNG) channels. In particularly preferred embodiments, the modified CNG channels exhibit increased sensitivity and specificity for cAMP, as compared to wild-type CNG channels. In additional embodiments, regulation by Ca2+-calmodulin has been removed in the modified CNG channels. Convenient optical methods for detecting changes in cAMP, taking advantage of the Ca2+ permeability of the channel are also provided by the present invention. In addition, electrophysiological methods are further provided.
    Type: Grant
    Filed: November 16, 2006
    Date of Patent: March 11, 2008
    Assignee: The Regents of the University of Colorado
    Inventors: Jeffrey W. Karpen, Thomas C. Rich, Dermot M. F. Cooper, Jerome Schaack, Kent Fagan
  • Modified cyclic nucleotide gated ion channels
    Publication number: 20070099226
    Abstract: The present invention provides modified cyclic nucleotide gated (CNG) channels. In particularly preferred embodiments, the modified CNG channels exhibit increased sensitivity and specificity for cAMP, as compared to wild-type CNG channels. In additional embodiments, regulation by Ca2+-calmodulin has been removed in the modified CNG channels. Convenient optical methods for detecting changes in cAMP, taking advantage of the Ca2+ permeability of the channel are also provided by the present invention. In addition, electrophysiological methods are further provided.
    Type: Application
    Filed: November 16, 2006
    Publication date: May 3, 2007
    Applicant: The Regents of the University of Colorado, a body corporate
    Inventors: Jeffrey Karpen, Thomas Rich, Dermot Cooper, Jerome Schaack, Kent Fagan
  • Nucleic acids encoding modified olfactory cyclic nucleotide gated ion channels
    Patent number: 7166463
    Abstract: The present invention provides modified cyclic nucleotide gated (CNG) channels. In particularly preferred embodiments, the modified CNG channels exhibit increased sensitivity and specificity for cAMP, as compared to wild-type CNG channels. In additional embodiments, regulation by Ca2+-calmodulin has been removed in the modified CNG channels. Convenient optical methods for detecting changes in cAMP, taking advantage of the Ca2+ permeability of the channel are also provided by the present invention. In addition, electrophysiological methods are further provided.
    Type: Grant
    Filed: November 15, 2002
    Date of Patent: January 23, 2007
    Assignee: The Regents of the University of Colorado
    Inventors: Jeffrey W. Karpen, Thomas C. Rich, Dermot M. F. Cooper, Jerome Schaack, Kent Fagan