Patents by Inventor Kent Goklen

Kent Goklen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Processes for isolation and purification of enfumafungin
    Patent number: 8674087
    Abstract: The present disclosure relates to processes useful in the isolation and purification of enfumafungin, which is classified as a triterpene glycoside antifungal compound and acts as a glucan synthase inhibitor. Enfumafungin has application in the treatment of conditions caused by fungal infection and is also useful as an intermediate in the preparation of other compounds useful as antifungal agents and/or inhibitors of (1,3)-?-D-glucan synthesis.
    Type: Grant
    Filed: August 30, 2010
    Date of Patent: March 18, 2014
    Assignee: Scynexis, Inc.
    Inventors: Jennifer M. Pollard, Rebecca A. Chmielowski, Lisa M. Dietrich, Francis P. Gailliot, Kent Goklen
  • PROCESSES FOR ISOLATION AND PURIFICATION OF ENFUMAFUNGIN
    Publication number: 20120165513
    Abstract: The present disclosure relates to processes useful in the isolation and purification of enfumafungin, which is classified as a triterpene glycoside antifungal compound and acts as a glucan synthase inhibitor. Enfumafungin has application in the treatment of conditions caused by fungal infection and is also useful as an intermediate in the preparation of other compounds useful as antifungal agents and/or inhibitors of (1,3)-?-D-glucan synthesis.
    Type: Application
    Filed: August 30, 2010
    Publication date: June 28, 2012
    Inventors: Jennifer M. Pollard, Rebecca A. Chmielowski, Lisa M. Dietrich, Francis P. Gailliot, Kent Goklen
  • Using amines or amino acids as mobile phase modifiers in chromatography
    Publication number: 20060014933
    Abstract: This invention relates to the use of amine, amino acid or amino acid ester mobile phase modifiers in normal phase chromatography to improve the resolution and/or productivity of peptide and lipopeptide purification. This chromatographic method can be used for either on analytical or preparative scale purification.
    Type: Application
    Filed: October 24, 2003
    Publication date: January 19, 2006
    Inventors: Kent Goklen, Joseph Nti-Gyabaah, Firorz Antia, Mary Dahlgren