Patents by Inventor Kent J. Johnson

Kent J. Johnson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Dimethyl-nonatetraenyl-trimethyl-cyclohexyl compounds and uses thereof
    Patent number: 11148998
    Abstract: This invention is in the field of medicinal chemistry. In particular, the invention relates to a new class of small-molecules having a dimethyl-nonatetraenyl-trimethyl-cyclohexyl structure useful as therapeutics for the treatment of subjects suffering from disorders characterized by abnormal proliferation and/or abnormal differentiation of cells, in particular of cells of which the growth and differentiation is sensitive to the actions of retinoids.
    Type: Grant
    Filed: May 23, 2018
    Date of Patent: October 19, 2021
    Assignee: The Regents of the University of Michigan
    Inventors: James Varani, Hollis Showalter, Andy White, Kent J. Johnson
  • DIMETHYL-NONATETRAENYL-TRIMETHYL-CYCLOHEXYL COMPOUNDS AND USES THEREOF
    Publication number: 20180339961
    Abstract: This invention is in the field of medicinal chemistry. In particular, the invention relates to a new class of small-molecules having a dimethyl-nonatetraenyl-trimethyl-cyclohexyl structure useful as therapeutics for the treatment of subjects suffering from disorders characterized by abnormal proliferation and/or abnormal differentiation of cells, in particular of cells of which the growth and differentiation is sensitive to the actions of retinoids.
    Type: Application
    Filed: May 23, 2018
    Publication date: November 29, 2018
    Inventors: James Varani, Hollis Showalter, Andy White, Kent J. Johnson
  • USE OF TWO BOTANICALS WITH COMPLEMENTARY ACTIVITIES FOR IMPROVEMENT OF SKIN
    Publication number: 20180008557
    Abstract: A skin augmentation composition comprises a therapeutically effective amount of a combination of a gingerol and a curcumin and a cosmetically or pharmaceutically acceptable carrier. Methods for enhancing the repair of damaged skin and the prevention of developing wounds in a subject having damaged skin comprises administering to a portion of damaged skin, a composition comprising a therapeutically effective amount of a combination of a gingerol and a curcumin and a cosmetically or pharmaceutically acceptable carrier.
    Type: Application
    Filed: September 20, 2017
    Publication date: January 11, 2018
    Inventors: James Varani, Kent J. Johnson
  • TUMOR SELECTIVE ANTIBODIES SPECIFIC TO ONCOFETAL ANTIGEN/IMMATURE LAMININ RECEPTOR PROTEIN
    Publication number: 20160229918
    Abstract: Disclosed are high affinity antibodies or antigen binding fragments thereof, which bind an epitope that lies within the C terminal region of oncofetal antigen (OFA)/immature laminin receptor protein (iLRP), and which do not substantially cross-react with mature OFA/LRP. The antibodies may be conjugated to cytotoxic moieties to enhance their therapeutic efficacy. Methods of making the antibodies and therapeutic and diagnostic uses thereof are also disclosed.
    Type: Application
    Filed: July 11, 2014
    Publication date: August 11, 2016
    Applicants: Benovus Bio, Inc., South Alabama Medical Science Foundation
    Inventors: Kent J. Johnson, Alton C. Morgan, Joseph A. Sinkule, James Varani, Joseph H. Coggin (Deceased), James W. Rohrer (Deceased), Adel L. Barsoum
  • TUMOR SELECTIVE ANTIBODIES SPECIFIC TO ONCOFETAL ANTIGEN/IMMATURE LAMININ RECEPTOR PROTEIN
    Publication number: 20150218287
    Abstract: Disclosed are high affinity antibodies or antigen-binding fragments thereof, which bind an epitope that lies within the C-terminal region of oncofetal antigen (OFA)/immature laminin receptor protein (iLRP), and which do not substantially cross-react with mature OFA/LRP. The antibodies may be conjugated to cytotoxic moieties to enhance their therapeutic efficacy. Methods of making the antibodies and therapeutic and diagnostic uses thereof are also disclosed.
    Type: Application
    Filed: February 4, 2015
    Publication date: August 6, 2015
    Applicants: BENOVUS BIO, INC., SOUTH ALABAMA MEDICAL SCIENCE FOUNDATION
    Inventors: Kent J. Johnson, Alton C. Morgan, Joseph A. Sinkule, James Varani, Joseph H. Coggin, JR., James W. Rohrer, Adel L. Barsoum
  • Use Of Two Botanicals With Complementary Activities For Improvement Of Skin
    Publication number: 20140328956
    Abstract: A skin augmentation composition comprises a therapeutically effective amount of a combination of a gingerol and a curcumin and a cosmetically or pharmaceutically acceptable carrier. Methods for enhancing the repair of damaged skin and the prevention of developing wounds in a subject having damaged skin comprises administering to a portion of damaged skin, a composition comprising a therapeutically effective amount of a combination of a gingerol and a curcumin and a cosmetically or pharmaceutically acceptable carrier.
    Type: Application
    Filed: July 17, 2014
    Publication date: November 6, 2014
    Inventors: James Varani, Kent J. Johnson