Patents by Inventor Kent J. Weinhold

Kent J. Weinhold has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Immune monitoring to predict and prevent infection
    Patent number: 10078076
    Abstract: Methods of evaluating the risk of infection after transplantation or immunosuppression in a subject are provided. Methods of determining whether a subject should be treated prophylactically with an anti-microbial agent are also provided herein. Kits for performing the methods described herein are also provided.
    Type: Grant
    Filed: November 26, 2014
    Date of Patent: September 18, 2018
    Assignee: Duke University
    Inventors: Scott M. Palmer, Kent J. Weinhold, Chi Wei Cliburn Chan, Laurie D. Snyder
  • IMMUNE MONITORING TO PREDICT AND PREVENT INFECTION
    Publication number: 20160377602
    Abstract: Methods of evaluating the risk of infection after transplantation or immunosuppression in a subject are provided. Methods of determining whether a subject should be treated prophylactically with an anti-microbial agent are also provided herein. Kits for performing the methods described herein are also provided.
    Type: Application
    Filed: November 26, 2014
    Publication date: December 29, 2016
    Applicant: Duke University
    Inventors: Scott M. Palmer, Kent J. Weinhold, Chi Wei Cliburn Chan, Laurie D. Snyder
  • Methods for identification of CDS8+ suppressor molecules
    Patent number: 7037645
    Abstract: The present invention relates to a bioactive molecule, herein referred to as the CD8+ suppressor molecule, that is produced by the CD8+ subset of human T-lymphocytes and suppresses type-1 human immunodeficiency virus (HIV-1) replication through inhibition of viral transcription. The invention relates to isolation of CD8+ cell lines and cell clones that produce that antiviral activity and to the development of assay systems for detection of the antiviral activity. The cell lines, cell clones and assay systems, described herein, may be utilized, e.g., to purify, characterize and clone the CD8+ suppressor molecule. The CD8+ suppressor molecule may have therapeutic applications for treatment of diseases associated with HIV-1 infection.
    Type: Grant
    Filed: February 6, 2002
    Date of Patent: May 2, 2006
    Assignee: Duke University
    Inventors: Dani P. Bolognesi, Michael L Greenberg, Simon F Lacey, Georgia D Tomaras, Kent J. Weinhold
  • Suppressor of HIV replication and transcription
    Patent number: 6528308
    Abstract: The present invention relates to a bioactive molecule, herein referred to as the CD8+ suppressor molecule, that is produced by the CD8+ subset of human T-lymphocytes and suppresses type-1 human immunodeficiency virus (HIV-1) replication through inhibition of viral transcription. The invention relates to isolation of CD8+ cell lines and cell clones that produce that antiviral activity and to the development of assay systems for detection of the antiviral activity. The cell lines, cell clones and assay systems, described herein, may be utilized, e.g., to purify, characterize and clone the CD8+ suppressor molecule. The CD8+ suppressor molecule may have therapeutic applications for treatment of diseases associated with HIV-1 infection.
    Type: Grant
    Filed: March 16, 2000
    Date of Patent: March 4, 2003
    Assignee: Duke University
    Inventors: Dani P. Bolognesi, Michael L. Greenberg, Simon F. Lacey, Georgia D. Tomaras, Kent J. Weinhold
  • Suppressor of HIV replication and transcription
    Publication number: 20020102538
    Abstract: The present invention relates to a bioactive molecule, herein referred to as the CD8+ suppressor molecule, that is produced by the CD8+ subset of human T-lymphocytes and suppresses type-1 human immunodeficiency virus (HIV-1) replication through inhibition of viral transcription. The invention relates to isolation of CD8+ cell lines and cell clones that produce that antiviral activity and to the development of assay systems for detection of the antiviral activity. The cell lines, cell clones and assay systems, described herein, may be utilized, e.g., to purify, characterize and clone the CD8+ suppressor molecule. The CD8+ suppressor molecule may have therapeutic applications for treatment of diseases associated with HIV-1 infection.
    Type: Application
    Filed: February 6, 2002
    Publication date: August 1, 2002
    Applicant: Duke University
    Inventors: Dani P. Bolognesi, Michael L. Greenberg, Simon F. Lacey, Georgia D. Tomaras, Kent J. Weinhold