Abstract: There is provided a friction stir spot joining device wherein stirring-related members are unitized to form a unitized stirring unit and an opening is formed in a friction stir spot joining device body for housing the unitized stirring unit therein. A stirring motor, a stirring shaft and a power transmission mechanism are unitized to form a stirring unit, and bearings of a linear motion guide are fixed to the stirring unit immediately under the stirring unit, and a ball nut is fixed to the back face of the stirring unit, wherein the friction stir spot joining device body is opened to form the opening at a rear upper portion through which the stirring unit is caused to move inside thereof.

Abstract: The present invention relates to a thienopyrrole compound represented by the following formula [I] wherein each symbol is as defined in the specification, or a pharmaceutically acceptable a salt thereof, and a hepatitis C virus (HCV) polymerase inhibitor and a therapeutic agent for hepatitis C containing this compound as an active ingredient. The compound of the present invention shows an anti-HCV activity based on the HCV polymerase inhibitory activity, and useful as an agent for the prophylaxis or treatment of hepatitis C.

Abstract: A rotary tool for friction stir spot welding including: a rod-like probe to be inserted into one side of stacked planar portions of plural metal members to be joined while being rotated; and a cylindrical shoulder member which is disposed coaxially outwardly of the probe and which has a shoulder surface to be abutted against the one side of the stacked portions while being rotated, wherein the probe and the shoulder member are individual components and are disposed so as to have a double-acting structure which enable them to move independently in their axial direction, and in which a gap between an inner surface of the shoulder member and an outer surface of the probe is formed to have a small gap on a tip side of the rotary tool and to have an enlarged gap having larger clearance than the small gap on a base portion side thereof.

Abstract: There is provided a friction stir spot joining device wherein stirring-related members are unitized to form a unitized stirring unit and an opening is formed in a friction stir spot joining device body for housing the unitized stirring unit therein. A stirring motor, a stirring shaft and a power transmission mechanism are unitized to form a stirring unit, and bearings of an LM guide (registered trademark) are fixed to the stirring unit immediately under the stirring unit, and a ball nut is fixed to the back face of the stirring unit, wherein the friction stir spot joining device body is opened to form the opening at a rear upper portion through which the stirring unit is caused to move inside thereof.

Abstract: The present invention relates to a fused ring compound represented by the following formula [I] wherein each symbol is as defined in the specification, or a pharmaceutically acceptable a salt thereof, and a hepatitis C virus (HCV) polymerase inhibitor and a therapeutic agent for hepatitis C containing this compound. The compound of the present invention shows an anti-HCV activity based on the HCV polymerase inhibitory activity, and useful as an agent for the prophylaxis or treatment of hepatitis C.

Abstract: There is provided a friction stir spot joining device in which a pin can be simply and surely caused to come in or come out from a tip end of the joining tool by driving a pin extraction motor. The friction stir spot joining device softens and stirs works to be joined by frictional heat generated by the rotation of a pin so as to perform spot joining and is provided with a stirring motor for rotating a joining tool having a pin, and a pressure application motor for linearly driving the joining tool. The friction stir spot joining device further has a pin extraction motor which is disposed at the rear of a stirring motor on the same axis line as the stirring motor and integrated with the stirring motor.

Abstract: A rotary tool for friction stir spot welding including: a rod-like probe to be inserted into one side of stacked planar portions of plural metal members to be joined while being rotated; and a cylindrical shoulder member which is disposed coaxially outwardly of the probe and which has a shoulder surface to be abutted against the one side of the stacked portions while being rotated, wherein the probe and the shoulder member are individual components and are disposed so as to have a double-acting structure which enable them to move independently in their axial direction, and in which a gap between an inner surface of the shoulder member and an outer surface of the probe is formed to have a small gap on a tip side of the rotary tool and to have an enlarged gap having larger clearance than the small gap on a base portion side thereof.

Abstract: The present invention relates to an aminopyridine compound represented by the following general formula (I) or a salt thereof and an Syk inhibitor containing the compound or a salt thereof as an active ingredient. Here, X1, X2, X3, Z, Y1, Y2 represent a carbon atom or a nitrogen atom, R, R1, R5, R6 represent a hydrogen atom, an alkyl group, etc., and R7 represents a hydrogen atom, a halogen atom, a nitro group, a cyano group, —CpH2(p-1)(Ra1)(Ra2)—O—Ra3, —C(?O)—Rd1, a 5- or 6-membered saturated heterocyclic group, an aromatic heterocyclic group, —N(Rh1)(Rh2), etc. The aminopyridine compound of the present invention has not only high Syk inhibitory activity but also properties to selectively inhibit Syk.

Abstract: The present invention relates to a thienopyrrole compound represented by the following formula [I] wherein each symbol is as defined in the specification, or a pharmaceutically acceptable a salt thereof, and a hepatitis C virus (HCV) polymerase inhibitor and a therapeutic agent for hepatitis C containing this compound as an active ingredient. The compound of the present invention shows an anti-HCV activity based on the HCV polymerase inhibitory activity, and useful as an agent for the prophylaxis or treatment of hepatitis C.

Abstract: There is provided a friction stir spot joining device in which a pin can be simply and surely caused to come in or come out from a tip end of the joining tool by driving a pin extraction motor when the pin extraction motor is used so as to cause the pin to come in or come out from the tip end of a joining tool. The friction stir spot joining device for softening and stirring works to be joined due to frictional heat generated by rotation of a pin so as to perform spot joining, and provided with a stirring motor for rotating a joining tool having a pin, and a pressure application motor for linearly driving the joining tool, said friction stir spot joining device further comprises a pin extraction motor which is disposed at the rear of a stirring motor on the same axis line as the stirring motor while integrated with the stirring motor.